Results 151 to 160 of about 663,827 (314)

Heparanase 2 (Hpa2) protects the exocrine pancreas from damages of Western diet and pancreatic cancer. [PDF]

open access: yesInt J Biol Sci
Kayal Y   +9 more
europepmc   +1 more source

O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu   +10 more
wiley   +1 more source

Microbiome: a driver of pancreatic inflammation and tumorigenesis. [PDF]

open access: yesTrends Cancer
Alam A   +4 more
europepmc   +1 more source

ANNULAR PANCREAS

open access: yesAnnals of Surgery, 1954
L, GILLETTE, B, LYNCH
openaire   +3 more sources

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

open access: yesAdvanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi   +23 more
wiley   +1 more source

Pancreatic Calculi: Two Case Reports and Literature Review. [PDF]

open access: yesClin Med Insights Case Rep
Aby Hadeer R   +6 more
europepmc   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

Early Endothelial Injury in Pancreas Transplantation: Insights from a Prospective Cohort Largely Composed of Simultaneous Pancreas-Kidney Recipients. [PDF]

open access: yesMed Sci (Basel)
Ferrer-Fàbrega J   +11 more
europepmc   +1 more source

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2000
G. Gradwohl   +3 more
semanticscholar   +1 more source

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