Results 151 to 160 of about 663,827 (314)
Heparanase 2 (Hpa2) protects the exocrine pancreas from damages of Western diet and pancreatic cancer. [PDF]
Kayal Y +9 more
europepmc +1 more source
O‐GlcNAcylated TAP1 Impairs Antigen Presentation and Promotes Immune Evasion in Bladder Cancer
This article unveils a critical mechanism of immune evasion in bladder cancer, which the O‐GlcNAc modification of TAP1 disrupts antigen presentation. This modification triggers HLA‐A degradation, shielding tumor cells from CD8+ T cell attack. The findings highlight targeting this pathway as a promising therapeutic avenue to sensitize tumors to ...
Jinpeng Wu +10 more
wiley +1 more source
Microbiome: a driver of pancreatic inflammation and tumorigenesis. [PDF]
Alam A +4 more
europepmc +1 more source
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi +23 more
wiley +1 more source
Pancreatic Calculi: Two Case Reports and Literature Review. [PDF]
Aby Hadeer R +6 more
europepmc +1 more source
A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
Early Endothelial Injury in Pancreas Transplantation: Insights from a Prospective Cohort Largely Composed of Simultaneous Pancreas-Kidney Recipients. [PDF]
Ferrer-Fàbrega J +11 more
europepmc +1 more source
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas.
G. Gradwohl +3 more
semanticscholar +1 more source

