Results 241 to 250 of about 749,373 (347)

Prognostic analysis of very early onset pancreatic cancer: a population-based analysis

, 2020
Dongjun Dai, Yanmei Wang, Xinyang Hu, Hongchuan Jin, Xian Wang   +4 more
openalex   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Chemotherapy Regimens and Survival in Pancreatic Cancer-A Ten-Year Single Centre Overview. [PDF]

Cancer Med
Tranvik H, Brandt F, Williamsson C, Sternby H.   +3 more
europepmc   +1 more source

A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene

, 2019
Cavin Wong, Fei Chen, Najmeh Alirezaie, Yifan Wang, Adeline Cuggia, Ayelet Borgida, Spring Holter, Tatiana Lenko, Céline Domecq, Gloria M. Petersen, Sapna Syngal, Randall E. Brand, Anil K. Rustgi, Michele L. Coté, Elena M. Stoffel, Sara H. Olson, Nicholas J. Roberts, Mohammad R. Akbari, Jacek Majewski, Alison P. Klein, Celia M.T. Greenwood, Steven Gallinger, George Zogopoulos   +22 more
openalex   +2 more sources

In Situ Engineering of Tumor Cells as Self‐Sustaining cDC1 Programming Factories for Effective Cancer Immunotherapy

Advanced Science, EarlyView.
The fused EV platform AS16‐EL@MPLA/p‐FX reprograms tumor cells into cytokine‐producing factories that continuously secrete XCL1 and FLT3L to recruit and differentiate cDC1s, while embedded MPLA activates them through TLR4 signaling and AS16 prevents their exhaustion, thereby enhancing antitumor immunity and establishing durable immune memory against ...
Shuiling Jin, Xiaoxi Wang, Bingyu Li, Xueqin Zhu, Zimai Liu, Jiao Lu, Yuanyuan Wei, Zixian Wu, Kai Li, Tiantian Zhang, Zonghong He, Pingping Zhu, Yuanming Qi, Benyu Liu, Hui Liu, Yongchao Wang, Zhenzhen Chen   +16 more
wiley   +1 more source

Mitochondrial superoxide dismutase controls metabolic plasticity in pancreatic cancer. [PDF]

Cell Commun Signal
Ramasubramanian S, Öllinger R, Eberhagen C, Zischka H, Schmid RM, Einwächter H.   +5 more
europepmc   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

Surgery based on resectability status of pancreatic cancer: a narrative review. [PDF]

Jpn J Clin Oncol
Einama T, Ohara M, Ichio K, Kobayashi K, Shinada H, Yonamine N, Tsunenari T, Takao M, Takihata Y, Ueno H, Kishi Y.   +10 more
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

B2M regulates ELANE in pyroptosis to affect pancreatic cancer progression. [PDF]

Transl Oncol
Xie H, Hu X, Cai Y, Zhu S, Deng Z.
europepmc   +1 more source