Results 231 to 240 of about 471,297 (330)

IL-17 in pancreatic disease: pathogenesis and pharmacotherapy.

open access: green, 2020
Fenglin Hu   +6 more
openalex   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu   +11 more
wiley   +1 more source

MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls

open access: green, 2013
Ang Li   +6 more
openalex   +2 more sources

CELLama: Foundation Model for Single Cell and Spatial Transcriptomics by Cell Embedding Leveraging Language Model Abilities

open access: yesAdvanced Science, EarlyView.
CELLama is created, a framework that harnesses language models to convert cellular data into “sentences” that represent gene expression and metadata, enabling a universal embedding of cells. Unlike most single‐cell foundation models, CELLama supports scalable analysis and offers flexible applications including spatial transcriptomics.
Jeongbin Park   +7 more
wiley   +1 more source

Protein N-Glycosylation Traits Combined with CA19-9 Accurately Distinguish Pancreatic Cancer Cases From Healthy Controls and Benign Pancreatic Diseases. [PDF]

open access: yesPancreas
Bogdanski AM   +11 more
europepmc   +1 more source

Pancreatic diseases register of the German society for general and visceral surgery

open access: diamond, 2019
Andrey Litvin   +3 more
openalex   +2 more sources

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