Results 91 to 100 of about 231,954 (279)

Imaging diagnosis and staging of pancreatic ductal adenocarcinoma: a comprehensive review

Insights into Imaging, 2020
Pancreatic ductal adenocarcinoma (PDAC) has continued to have a poor prognosis for the last few decades in spite of recent advances in different imaging modalities mainly due to difficulty in early diagnosis and aggressive biological behavior. Early PDAC
Khaled Y. Elbanna, H. Jang, T. Kim
semanticscholar   +1 more source

Endoscopic Ultrasound Can Differentiate High-Grade Pancreatic Intraepithelial Neoplasia, Small Pancreatic Ductal Adenocarcinoma, and Benign Stenosis

Gut and Liver
Background/Aims: High-grade pancreatic intraepithelial neoplasia and invasive pancreatic ductal adenocarcinoma ≤10 mm are targets for early detection of pancreatic cancer. However, their imaging characteristics are unknown.
Ryota Sagami, Kentaro Yamao, Ryuki Minami, Jun Nakahodo, Hidetoshi Akiyama, Hidefumi Nishikiori, Kazuhiro Mizukami, Kenji Yamao, Vikram Bhatia, Yuji Amano, Kazunari Murakami   +10 more
doaj   +1 more source

Prognostic and diagnostic value of REG4 serum and tissue expression in pancreatic ductal adenocarcinoma

Tumor Biology, 2018
Expression of regenerating islet-derived protein 4 (REG4), a secretory protein involved in cell differentiation and proliferation, is upregulated in inflammatory bowel diseases and in many gastrointestinal malignancies. The prognostic significance of its
Kapo Saukkonen, Jaana Hagström, Harri Mustonen, Laura Lehtinen, Olli Carpen, Leif C Andersson, Hanna Seppänen, Caj Haglund   +7 more
doaj   +1 more source

Pictorial Review of Rare Pancreatic Tumors and Tumor-Like Lesions

대한영상의학회지, 2020
Various types of tumors and tumor-like lesions may affect the pancreas. Among them, pancreatic ductal adenocarcinoma is the most common and is generally referred to as “pancreatic cancer.” Recently, the detection rates of rare pancreatic tumors and ...
Seung Jae Lee, Sang Soo Shin, Suk Hee Heo, Yong Yeon Jeong   +3 more
doaj   +1 more source

The dark side of ferroptosis in pancreatic cancer

OncoImmunology, 2021
Drug-induced ferroptosis, an iron-dependent regulatory necrosis, has been proposed for the therapy of pancreatic ductal adenocarcinoma. However, genetically engineered mouse models have revealed that high-iron diets or deletion of pancreatic GPX4 (a key ...
Jiao Liu, Enyong Dai, Rui Kang, Guido Kroemer, Daolin Tang   +4 more
doaj   +1 more source

Differential and Joint Effects of Metformin and Statins on Overall Survival of Elderly Patients with Pancreatic Adenocarcinoma: A Large Population-Based Study. [PDF]

, 2017
Background: Published evidence indicates that individual use of metformin and statin is associated with reduced cancer mortality. However, their differential and joint effects on pancreatic cancer survival are inconclusive.Methods: We identified a large ...
Demissie, Kitaw, E, Jian-Yu, Graber, Judith M., Lin, Yong, Lu, Shou-En, Lu-Yao, Grace, Petersen, Gloria M., Rotter, David, Tan, Xiang-Lin, Zhang, Lanjing   +9 more
core   +2 more sources

Fully Automatic Deep Learning Framework for Pancreatic Ductal\n Adenocarcinoma Detection on Computed Tomography [PDF]

, 2021
Natália Alves, Megan Schuurmans, Geke Litjens, Joeran S. Bosma, John J. Hermans, Henkjan Huisman   +5 more
openalex   +1 more source

Deciphering the Crosstalk Between Myeloid-Derived Suppressor Cells and Regulatory T Cells in Pancreatic Ductal Adenocarcinoma

Frontiers in Immunology, 2020
Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with rising incidence and a remarkable resistance to current therapies. The reasons for this therapeutic failure include the tumor's extensive infiltration by immunosuppressive cells such as ...
C. Siret, Aurélie Collignon, F. Silvy, S. Robert, Thierry Cheyrol, P. André, V. Rigot, J. Iovanna, S. A. van de Pavert, D. Lombardo, E. Mas, Anna R Martirosyan   +11 more
semanticscholar   +1 more source

Desmoplasia of Pancreatic Ductal Adenocarcinoma [PDF]

Clinical Gastroenterology and Hepatology, 2009
Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer and is characterized by remarkable desmoplasia. The desmoplasia is composed of extracellular matrix (ECM) proteins, myofibroblastic pancreatic stellate cells, and immune cells associated with a multitude of cytokines, growth factors, and ECM metabolizing enzymes.
Stephen, Pandol, Mouad, Edderkaoui, Ilya, Gukovsky, Aurelia, Lugea, Anna, Gukovskaya   +4 more
openaire   +2 more sources

Antineoplastic effects of auranofin in human pancreatic adenocarcinoma preclinical models

Surgery Open Science, 2019
Background: Auranofin, a Food and Drug Administration–approved anti-rheumatic agent with anticancer properties for lung and ovarian cancer, has never been studied for pancreatic cancer.
Mayrim V. Rios Perez, David Roife, Bingbing Dai, Michael Pratt, Ryszard Dobrowolski, Ya'an Kang, Xinqun Li, Jithesh J. Augustine, Rafal Zielinski, Waldemar Priebe, Jason B. Fleming   +10 more
doaj   +1 more source