Results 211 to 220 of about 217,476 (395)

Exosomal delivery of CRISPR/Cas9 complexes for targeted editing of KRAS^G12D in pancreatic cancer: prerequisites for clinical surgical application

Український журнал клінічної хірургії
Objective. To evaluate exosomes obtained from patients with ductal adenocarcinoma of the pancreas as carriers of CRISPR/Cas9 complexes for targeted editing of KRAS^G12D in pancreatic cancer and to test their stability, editing efficiency, and ...
S. M. Gramatyuk, Yu. V. Ivanova, I. M. Mamontov, I. A. Kryvoruchko, E. Hubbard, K. Sargsyan   +5 more
doaj   +1 more source

Pancreatico-Duodenectomy for Pancreatic Ductal Adenocarcinoma: from Artery-First Approaches toTRIANGLE Operation

, 2022
Traian Dumitraşcu, Irinel Popescu
openalex   +1 more source

Nanogel‐Mediated Immunotherapy to Tackle Cancer and Inflammatory Diseases

ChemistryEurope, EarlyView.
Nanogels formed through self‐assembly, microemulsion, or precipitation polymerization method enable precise delivery of immunotherapeutic factors and immune cell targeting, thus effectively modulating immune responses. This review highlights recent advances in stimuli‐responsive nanogel design, underlying mechanisms, and their potentials to tackle ...
Ziwen Zhang, Jinxia Wang, Guang‐Zhi Jin, István Bányai, Dzmitry Shcharbin, Ivan Stoikov, Mingwu Shen, Xiangyang Shi   +7 more
wiley   +1 more source

Iron-Dependent Cell Death: A New Treatment Approach against Pancreatic Ductal Adenocarcinoma [PDF]

, 2023
Carlos Lopez-Blazquez, Carlos Lacalle-González, Lara Sanz-Criado, Michael Ochieng’ Otieno, Jesús García‐Foncillas, Javier Martínez‐Useros   +5 more
openalex   +1 more source

Comparative Effect of African Walnut Oil and Docosahexaenoic Acid on, Cancer Antigen C15‐3, Biochemical and Histopathological Markers of Female Wistar Rats With 7,12‐Dimethylbenz[a]anthracene‐Induced Breast Cancer

Cancer Nexus, EarlyView.
ABSTRACT This work compares the effect of African walnut oil and docosahexaenoic acid (DHA) on cancer antigen C15‐3 (CA15‐3), biochemical, and histopathological markers of rats with 7,12‐dimethylbenz[a]anthracene‐induced (DMBA) breast cancer. 18 rats with tumor were randomized into three groups of six rats each: The negative control, the positive ...
Fabrice Tonfack Djikeng, Brenda Sandrine Tiadjo, Eurydice Flore Tiepma Ngongang, Hilaire Macaire Womeni   +3 more
wiley   +1 more source

A Phase Ib/II Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma [PDF]

Andrew L. Coveler, Matthew J. Reilley, Mark M. Zalupski, Teresa Macarulla, Christos Fountzilas, Mariano Ponz‐Sarvisé, Adnan Nagrial, Nataliya V. Uboha, Sophia Frentzas, Michael J. Overman, Anne M. Noonan, Wells A. Messersmith, Nick Pavlakis, Niharika B. Mettu, Ina Bisha, Ying Wang, Paul Smith, Elina Murtomaki, Agata A. Bielska, Véronique Bragulat, Zachary A. Cooper, Rakesh Kumar, David R. Spigel   +22 more
openalex   +1 more source

Comparison of oncologic outcomes between open and laparoscopic distal pancreatectomy for pancreatic ductal adenocarcinoma using data from the KOTUS-BP national database: overcoming selection bias and the necessity of definite indications

, 2022
Hongbeom Kim, Jin Seok Heo, Chang Moo Kang, Ho Kyoung Hwang, Ho‐Seong Han, Yoo‐Seok Yoon, Joon Seong Park, Sung‐Sik Han, Yong‐Hoon Kim, Jinsun Lee, Young‐Dong Yu, In Seok Choi, Jae Do Yang, Young Hoon Roh, Seong-Ryong Kim, Jun-Chul Chung, Sang Hwa Song, Song Cheol Kim, Jin‐Young Jang   +18 more
openalex   +2 more sources

Cytological Features of Pancreatic Medullary Carcinoma Diagnosed by Endoscopic Ultrasound‐Guided Fine Needle Aspiration

Diagnostic Cytopathology, EarlyView.
ABSTRACT Pancreatic medullary carcinoma is an extremely rare tumor classified as a histological subtype of pancreatic ductal adenocarcinoma. We report a case of a pancreatic medullary carcinoma and describe its cytological features. A 75‐year‐old woman presented with lower back pain, epigastric discomfort, and a tumor‐like lesion in the pancreatic body.
Urara Okawa, Keishi Mizuguchi, Miyu Okuda, Tatsuya Mori, Hiroko Ikeda   +4 more
wiley   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Supplementary Methods from A Visually Apparent and Quantifiable CT Imaging Feature Identifies Biophysical Subtypes of Pancreatic Ductal Adenocarcinoma

, 2023
Eugene J. Koay, Yeon‐Ju Lee, Vittorio Cristini, John Lowengrub, Ya’an Kang, F. Anthony San Lucas, Brian P. Hobbs, Rong Ye, Dalia Elganainy, Muayad F. Almahariq, Ahmed Amer, Deyali Chatterjee, Huaming Yan, Peter C. Park, Mayrim V. Rios Perez, Dali Li, Naveen Garg, Kim A. Reiss, Shun Yu, Anil K. Chauhan, Mohamed Zaid, Newsha Nikzad, Robert A. Wolff, Milind Javle, Gauri R. Varadhachary, Rachna T. Shroff, Prajnan Das, Jeffrey E. Lee, Mauro Ferrari, Anirban Maitra, Cullen M. Taniguchi, Michael P. Kim, Christopher H. Crane, Matthew H. G. Katz, Huamin Wang, Priya Bhosale, Eric P. Tamm, Jason B. Fleming   +37 more
openalex   +1 more source