Results 251 to 260 of about 217,476 (395)

Development of a consensus molecular classifier for pancreatic ductal adenocarcinoma. [PDF]

Genome Med
Villoslada-Blanco P, Alonso L, Sabroso-Lasa S, Maquedano M, Estudillo L, Real FX, López de Maturana E, Malats N.   +7 more
europepmc   +1 more source

Table S1-3 from CXCR4 in Tumor Epithelial Cells Mediates Desmoplastic Reaction in Pancreatic Ductal Adenocarcinoma

, 2023
Toshihiro Morita, Yuzo Kodama, Masahiro Shiokawa, Katsutoshi Kuriyama, Saiko Marui, Takeshi Kuwada, Yuko Sogabe, Tomoaki Matsumori, Nobuyuki Kakiuchi, Teruko Tomono, Atsushi Mima, Tatsuki Ueda, Motoyuki Tsuda, Yuki Yamauchi, Yoshihiro Nishikawa, Yojiro Sakuma, Yuji Ota, Takahisa Maruno, Norimitsu Uza, Takashi Nagasawa, Tsutomu Chiba, Hiroshi Seno   +21 more
openalex   +1 more source

Collagen Signaling via DDR1 Exacerbates Barriers to Macromolecular Drug Delivery in a 3D Model of Pancreatic Cancer Fibrosis

Small, EarlyView.
This work investigates the role of collagen I signaling in the fibrotic barrier to macromolecular drug delivery in pancreatic cancer. Mechanistic analyses revealed the involvement of the receptor tyrosine kinase DDR1 signaling through PI3K/AKT/mTOR.
Mayu Ohira, Moe Kitamura, Hiroyo Iwasaki, Haruko Ohta‐Okano, Hiyori Tsujii, Reika Nakamura, Takuya Nakazawa, Akihiro Nishiguchi, Masaya Yamamoto, Kensuke Osada, Shinichi Toyooka, Horacio Cabral, Atsushi Masamune, Mitsunobu R. Kano, Hiroyoshi Y. Tanaka   +14 more
wiley   +1 more source

Editorial: Exploring microbial interactions in pancreatic ductal adenocarcinoma microenvironment. [PDF]

Front Oncol
Veschi S, Di Sebastiano P, Mincione G.
europepmc   +1 more source

High Burden of Pancreatic Surgery for Intraductal Papillary Mucinous Neoplasia With Low‐Grade Dysplasia and Benign Cysts: A Systematic Review and Meta‐Analysis

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Intraductal papillary mucinous neoplasms with low‐grade dysplasia (IPMNs w/LGD) and benign cysts, including serous cystadenomas (SCAs), are common pancreatic cystic lesions (PCLs) that are better managed conservatively. The burden of patients who undergo surgical resection for these cysts is unknown.
Samuel Tanner, Priyata Dutta, Elit Quingalahua, Jean M. Chalhoub, Fadi Hawa, Antonio Facciorusso, Gabriele Capurso, Un‐Jung Lee, Jorge D. Machicado   +8 more
wiley   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Surgical decision-making after neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma. [PDF]

Ann Surg Treat Res
Lee H.
europepmc   +1 more source

Organoid‐based novel technology for antitumor drug screening

VIEW, EarlyView.
Organoids represent a cutting‐edge research model that closely mimics in vivo organ physiology, making them highly valuable for tumor immunotherapy drug screening. This review explores the integration of organoids with advanced technologies, such as gene editing, 3D bioprinting, and AI, highlighting novel fusion platforms and their applications.
Yu Su, Yuan Chen, Guanning Wei, Yihai Shi   +3 more
wiley   +1 more source

Differential Control of Growth and Identity by HNF4α Isoforms in Pancreatic Ductal Adenocarcinoma. [PDF]

Mol Cancer Res
Fang P, Wilson ER, Larsen SN, Orellana WA, Hall MA, Stubben C, Kabir AH, Affolter K, Moffitt RA, Zhang X, Snyder EL.   +10 more
europepmc   +1 more source

New Function Annotation of PROSER2 in Pancreatic Ductal Adenocarcinoma

Yu‐Sun Lee, Ji-Eun Im, Yeji Yang, Hea Ji Lee, Mi Rim Lee, Sang Myung Woo, Sang‐Jae Park, Sun‐Young Kong, Jin Young Kim, Heeyoun Hwang, Yun‐Hee Kim   +10 more
openalex   +1 more source