Results 121 to 130 of about 78,794 (295)

Randomized phase III trial of intravenous and intraperitoneal paclitaxel with S-1 versus gemcitabine plus nab-paclitaxel for pancreatic ductal adenocarcinoma with peritoneal metastasis (SP study) [PDF]

open access: gold, 2022
Tomohisa Yamamoto   +18 more
openalex   +1 more source

Autocrine Netrin‐1 Signaling in Hepatic Stellate Cells Drives Liver Fibrosis and Diet‐Induced Metabolic Dysfunction‐Associated Steatohepatitis in Mice

open access: yesAdvanced Science, EarlyView.
Netrin‐1 expression is upregulated in hepatic stellate cells (HSCs) during metabolic dysfunction–associated steatohepatitis and injury‐mediated liver fibrosis. Secreted Netrin‐1 establishes an autocrine positive feedback loop by binding to UNC5B receptors on HSCs.
Jiahui Zhao   +8 more
wiley   +1 more source

Reversed Z-shaped anomaly of main pancreatic duct as a cause of recurrent acute pancreatitis: A review

open access: yesJournal of Dr. NTR University of Health Sciences, 2016
Idiopathic pancreatitis comprises of around 20% cases of acute pancreatitis. We report a case with reversed Z-type main pancreatic duct, a very rare and unusual anomaly of the main pancreatic duct as a cause for idiopathic acute pancreatitis. A review of
Amarnath Kadimella   +2 more
doaj   +1 more source

Improved outcomes with minimally invasive pancreaticoduodenectomy in patients with dilated pancreatic ducts: a prospective study. [PDF]

open access: yesSurg Endosc, 2022
Cos H   +14 more
europepmc   +1 more source

A Case of Groove Pancreatic Cancer Diagnosed through Biliary Peritonitis Due to Intrahepatic Bile Duct Rupture

open access: diamond, 2021
Tohru Nishimura   +10 more
openalex   +2 more sources

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh   +8 more
wiley   +1 more source

Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease. [PDF]

open access: yesGut, 2021
Martens S   +25 more
europepmc   +1 more source

Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines

open access: yesAdvanced Science, EarlyView.
Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira   +18 more
wiley   +1 more source

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