Results 31 to 40 of about 51,365 (299)

Update on the diagnosis and management of exocrine pancreatic insufficiency [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Exocrine pancreatic insufficiency (EPI) is characterized by inadequate pancreatic enzyme delivery to the small intestine Exocrine pancreatic insufficiency (EPI) is characterized by inadequate pancreatic enzyme delivery to the small intestine, resulting ...
Yaseen Perbtani, Chris E. Forsmark
doaj   +1 more source

Estrogens promote misfolded proinsulin degradation to protect insulin production and delay diabetes [PDF]

open access: yes, 2018
Summary: Conjugated estrogens (CE) delay the onset of type 2 diabetes (T2D) in postmenopausal women, but the mechanism is unclear. In T2D, the endoplasmic reticulum (ER) fails to promote proinsulin folding and, in failing to do so, promotes ER stress and
Allard, Camille   +12 more
core   +2 more sources

Pancreatic enzyme replacement therapy: exocrine pancreatic insufficiency after gastrointestinal surgery [PDF]

open access: yesHPB, 2009
Exocrine pancreatic insufficiency (EPI) and resultant maldigestion occurs in up to 80% of patients following gastric, duodenal or pancreatic surgery. Accurate diagnosis is required to determine the appropriate intervention, but the conventional method of faecal fat quantification is time-consuming and not always readily available.
openaire   +2 more sources

Pancreatic enzyme replacement therapy for young cystic fibrosis patients [PDF]

open access: yesJournal of Cystic Fibrosis, 2009
Maldigestion in cystic fibrosis (CF) affects approximately 90% of patients. As soon as pancreatic insufficiency is identified, enzyme supplementation is prescribed even with breast fed infants. A pancreatic enzyme preparation developed particularly for infants, Creon for children (CfC), contains smaller granules to be administered with a dosing spoon ...
Munck, Anne   +15 more
openaire   +2 more sources

Correction of Secondary Insufficiency of Exocrine Pancreatic Function in Children with Combined Pathology of the Gastrointestinal Tract

open access: yesZdorovʹe Rebenka, 2012
The article analyzed the data of world literature on problems of clinical significance, diagnosis and treatment of pancreatic exocrine insufficiency. Own study of pancreatic function in children with diseases and functional disorders of the digestive ...
Yu.V. Marushko, Yu.I. Todyka
doaj   +1 more source

Nutrition in children with exocrine pancreatic insufficiency

open access: yesFrontiers in Pediatrics, 2023
Exocrine pancreatic insufficiency (EPI) is a condition defined as pancreatic loss of exocrine function, including decreased digestive enzymes and bicarbonate secretion, which leads to maldigestion and malabsorption of nutrients.
Yuhua Zheng, Shikib Mostamand
doaj   +1 more source

Investigation of lipid digestion by fungal and porcine lipase supplements for severe pancreatic insufficiency using the in vitro dynamic TIM model

open access: yesBritish Journal of Pharmacy, 2023
Exocrine pancreatic insufficiency (EPI) is caused by insufficient secretion or limited activity of pancreatic enzymes, especially lipase. Chronic pancreatitis (CP) is the most common EPI disease.
Tânia Martins Garcia   +3 more
doaj   +1 more source

Essential Role of Lyn in Fibrosis. [PDF]

open access: yes, 2016
Fibrotic disorders involve replacement of normal parenchyma with myofibroblasts, which deposit connective tissue, leading to obliteration of the function of the underlying organ.
Birtolo, Chiara   +10 more
core   +2 more sources

Effectivity of Pancreatic Enzyme Replacement Therapy in Malnourished Children

open access: yesJournal of Pediatric Gastroenterology and Nutrition, 2020
ABSTRACTObjective:Malnutrition is commonly seen in children with exocrine pancreatic insufficiency (EPI). Pancreatic enzyme replacement therapy (PERT) is the mainstay treatment of acute malnutrition in children detected with a disease closely associated with EPI (eg, cystic fibrosis).
GÜVEN, BURCU   +3 more
openaire   +4 more sources

EXOCRINE PANCREATIC INSUFFICIENCY IN CHILDREN WITH TYPE 1 DIABETES MELLITUS: A NEW PROBLEM OF PEDIATRIC GASTROENTEROLOGY

open access: yesВопросы современной педиатрии, 2013
One of the complications of diabetes mellitus is the development of pancreatic exocrine insufficiency. Fecal elastase 1 is a good marker of pancreatic exocrine secretion.
A. A. Nizhevich   +4 more
doaj   +1 more source

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