Results 71 to 80 of about 357,399 (291)
Clinical features of different variants of excretory pancreatic insufficiency
Aim. To analyse course of excretory pancreatic insufficiency (EPI) of pancreatic and not origin as well as factors associated with its development. Material and methods.
Mariya Fedorovna Osipenko +3 more
doaj
Pancreatic exocrine insufficiency (PEI) is characterized by inadequate synthesis, secretion, and/or activation of exocrine pancreatic secretions. This guideline has been developed to assist clinicians and researchers in understanding the definition ...
Orhan Sezgin +5 more
doaj +1 more source
The aim of publication. To present the modern concept of etiology and pathogenesis of exocrine pancreatic insufficiency to general practitioners as well as with the established approach to diagnostics and treatment of this syndrome. Summary.
V. T. Ivashkin +11 more
doaj +1 more source
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source
Exocrine pancreatic insufficiency (EPI) is characterised by the pancreas’s inadequate synthesis or release of digestive enzymes, which impairs digestion and causes nutritional malabsorption.
Laiba Imran +7 more
core +1 more source
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Rational Prescribing of Pancreatic Enzymes for Patients with Pancreatic Cancer
Most patients with pancreatic cancer at some point present with symptoms related to exocrine pancreatic insufficiency (EPI). These include diarrhea, abdominal bloating, indigestion, steatorrhea, weight loss, and anorexia.
Mary Acelle G. Garcia +3 more
doaj +1 more source
Pancreatic function assessment
Several non invasive tests are available to assess pancreatic function, but no one is routinely used in clinical practice to diagnose chronic pancreatitis, due to their poor sensitivity in diagnosing mild pancreatic insufficiency.
Ojetti, Veronica +7 more
core
Diagnosis and treatment of pancreatic exocrine insufficiency
Pancreatic exocrine insufficiency is an important cause of maldigestion and a major complication in chronic pancreatitis. Normal digestion requires adequate stimulation of pancreatic secretion, sufficient production of digestive enzymes by pancreatic ...
Lindkvist, Björn,
core +1 more source

