The Diabetic Dog as a Translational Model for Human Islet Transplantation. [PDF]
, 2017 The dog model has served as the primary method for early development of many diabetes therapies, including pancreatic islet transplantation techniques and immunosuppressive protocols.
Adin, Christopher A, Gilor, Chen
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Functional and Morphological Characteristics of Pancreatic Islet Lesions Induced by Quinolone Antimicrobial Agent Gatifloxacin in Rats [PDF]
, 2018 Koichi Yabe +4 more
openalex +1 more source
Early adversity and the comorbidity between metabolic disease and psychopathology
The Journal of Physiology, EarlyView.Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
Telmisartan, when compared to losartan, shows additional beneficial effects to pancreatic islet structure and function in diet-induced obese mice [PDF]
, 2015 Francielle Graus‐Nunes +7 more
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The Journal of Physiology, EarlyView.Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand +2 more
wiley +1 more source
Vitamin D Receptor Activation Induces Peptide YY Transcription in Pancreatic Islets [PDF]
, 2012 Mihwa Choi +5 more
openalex +1 more source
Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation
The Journal of Physiology, EarlyView.Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson +7 more
wiley +1 more source
Exenatide protects pancreatic islets against brain death-induced inflammation and viability loss [PDF]
, 2014 Rodrigo Carlessi +5 more
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Prevention of Lipotoxicity in Pancreatic Islets with Gammahydroxybutyrate [PDF]
, 2022 Justin Hou Ming Yung +10 more
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The Journal of Physiology, EarlyView.Abstract figure legend Effects of sustained oxygen and glucose supplementation on growth and cellular proliferation in growth‐restricted fetuses. This study evaluated whether supplemental oxygen and glucose could improve growth rates in sheep fetuses with established fetal growth restriction (FGR). Following the induction of placental insufficiency and
Mariangel Varela +9 more
wiley +1 more source