Results 171 to 180 of about 115,516 (324)

Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta‐Cell Function

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In the non‐diabetic beta‐cell (top left) activation of glucokinase (bottom left) leads to inhibition of mitochondrial metabolism and thereby impairs insulin secretion. The effect is similar to that of chronic hyperglycaemia as seen in the diabetic beta‐cell (top right).
Matthew Lloyd, Natascia Vedovato, Samuel J. Mullan, Alice Elphick, Aerin J. Dumenil, Chantal Rufer, Alexandra C. Title, Burcak Yesildag, Elizabeth Haythorne, Frances M. Ashcroft   +9 more
wiley   +1 more source

Transfer of genes for IL-10 and TGF-β to isolated human pancreatic islets

, 1997
Shaoping Deng, Z Yang, Robert J. Ketchum, Taras Kucher, Markus Weber, Abraham Shaked, Ali Naji, Kenneth L. Brayman   +7 more
openalex   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Spontaneous Pancreatic Islet Amyloidosis in a Greater White-nosed Guenon (Ceropithecus nictitans)

, 2005
Hyo‐Jung Kwon, Mi‐Sun Park, Nam-Sik Shin, Doo‐Youn Cho, Dae-Yong Kim, Yang‐Kyu Choi   +5 more
openalex   +2 more sources

Pancreatic cancer triggers diabetes through TGF-β–mediated selective depletion of islet β-cells [PDF]

, 2020
Parash Parajuli, Thien Ly Nguyen, Céline Prunier, Mohammed S. Razzaque, Keli Xu, Azeddine Atfi   +5 more
openalex   +1 more source

Functional Segregation of Pancreatic Microcirculation Reveals Sex‐Dependent Microhemodynamic Signatures

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Pancreatic exocrine microcirculation exhibits sexual dimorphism arising from steroid–genetic interactions. Laser Doppler flowmetry combined with wavelet analysis identifies a male passive coupling phenotype aligned with systemic pressure and a female active vasomotion phenotype driven by ERβ‐mediated, NO‐dependent oscillations.
Yuan Li, Yingyu Wang, Bing Wang, Qin Ouyang, Weiqi Liu, Xiang Xu, Xu Zhang, Mingming Liu, Ruijuan Xiu   +8 more
wiley   +1 more source

Intrathecal Allotransplantation of Rat Pancreatic Islets by Lumbar Puncture

, 1994
Yasuhisa Hara, Hiroshi Taniguchi
openalex   +2 more sources

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa, Katsuya Kitamura, Kei Yamamoto, Kenichi Tadokoro, Yasunosuke Akita, Jun Uemura, Fumito Yamanishi, Masakazu Abe, Munehide Nakatsugawa, Takao Itoi   +9 more
wiley   +1 more source

A Case of Pancreatic Neuroendocrine Tumor Growing Intraductal Extension toward the Main Pancreatic Duct Complicated by Thrombocytopenia: Diagnostic Challenges and Management Strategy

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We present a rare and diagnostically challenging case of a pancreatic neuroendocrine tumor (pNET) with intraductal growth into the main pancreatic duct (MPD), complicated by severe thrombocytopenia due to myelodysplastic syndrome. A 37‐year‐old male presented with thrombocytopenia.
Koichi Soga, Kazuma Sakakibara, Yuki Soma, Manayu Shiina, Mayumi Yamaguchi, Masaru Kuwada, Ryosaku Shirahashi, Ikuhiro Kobori, Shinichi Ban, Masaya Tamano   +9 more
wiley   +1 more source

Measurements of cytoplasmic free Ca²⁺ concentration in human pancreatic islets and insulinoma cells [PDF]

, 1991
Hendrik Kindmark, Martin Köhler, Thomas Nilsson, Per Arkhammar, Karl-Ludvig Wiechel, Patrik Rorsman, Suad Efendić, Per‐Olof Berggren   +7 more
openalex   +1 more source