Transformations in Diabetes Care: Lessons From Commons‐Based, Peer‐Produced Citizen Science
Sociology of Health &Illness, Volume 48, Issue 2, February 2026.ABSTRACT Medical technologies have historically been the domain of private entities and public institutions. However, this market–state model is being challenged by commons‐based, peer‐produced citizen science. Here, we present a community of people with diabetes, which has developed life‐critical medical devices through open‐source innovation, as a ...
Shane O'Donnell, Muireann Quigley
wiley +1 more source
The antigen presentation landscape of cytokine-stressed human pancreatic islets. [PDF]
Cell RepNanaware PP +15 more
europepmc +1 more source
Chronic GIPR agonism results in pancreatic islet GIPR functional desensitisation
Iona Davies +8 more
openalex +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.This work proposes ferroptosis as a mechanistic driver of age‐related muscle dysfunction, whereby iron dyshomeostasis and impaired antioxidant capacity promote lipid peroxidation, and eventually trigger ferroptosis, leading to muscle wasting, and ultimately contributing to weakness and functional decline with aging.
Rola S. Zeidan +6 more
wiley +1 more source
Assessing the rate dependence of the first phase of glucose-stimulated insulin secretion: dynamic perifusion studies with isolated human pancreatic islets. [PDF]
Am J Physiol Endocrinol MetabBuchwald P +3 more
europepmc +1 more source
Aging Cell, Volume 25, Issue 2, February 2026.Partial chemical reprogramming significantly increases mitochondrial interaction networks, affects mitochondrial morphology, speeds up mitochondrial movement dynamics, increases mitochondrial transmembrane potential, and induces TCA cycle stress. These changes in mitochondrial function contribute to lipid droplet accumulation, acute kidney injury, and ...
Wayne Mitchell +9 more
wiley +1 more source
Exploring Sex-Specific Mechanisms in Type 2 Diabetes Mellitus by Single-Cell Analysis in Pancreatic Islets. [PDF]
Endocrinol Metab (Seoul)Lee J.
europepmc +1 more source
Steroid effects on intracellular degradation of insulin and crinophagy in isolated pancreatic islets
, 2007 Monica Sandberg, Lisa Borg
openalex +2 more sources
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry +2 more
wiley +1 more source
Modelling the effects of human SUR1 R1420H variation on insulin secretory function using isogenic iPSC-derived pancreatic islets. [PDF]
DiabetologiaNair AK +7 more
europepmc +1 more source