Results 121 to 130 of about 39,716 (234)

Chronic ulcerative oesophagitis rich in IgG4‐positive plasma cells – a distinct clinicopathological entity

Histopathology, Volume 89, Issue 1, Page 47-57, July 2026.
We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger, Ian Brown, Anthony J Gill, Tomas Slavik, Giuseppe Zamboni, Cord Langner   +5 more
wiley   +1 more source

Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review

Obesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso, Flávia Campos Corgosinho, Deborah Cristina Landi Masquio, Nayra Figueiredo, Fabiana Kattah, Cintia Cercato, Lian Tock, Raquel Munhoz da Silveira Campos   +7 more
wiley   +1 more source

Maternal Obesity and MicroRNAs in Breast Milk: Implications for Infant Developmental Programming

Obesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT This review explores the relationship between maternal obesity and alterations in the expression of microRNAs (miRNAs) in breast milk, highlighting how these changes may influence the developmental programming of the infant. Evidence suggests that maternal obesity can affect the bioactive composition of breast milk, including miRNA profiles ...
Gyslane M. Santos, Fabíola Isabel Suano de Souza, Luciana P. Pisani   +2 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, Volume 16, Issue 6, Page 1197-1212, June 2026.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog

Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann, Milena Carolina Paz, Paola Sônego, Ana Carolina Contri Natal, Lívia Surita, Marcele Bettim Bandinelli, Luciana Sonne   +6 more
wiley   +1 more source

Distinct Germline Mutation Landscape and Clinical Implications in Chinese Colorectal Cancer: A Large‐Scale Genomic Analysis of 1094 Patients

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Objective To investigate the prevalence, characteristics, and clinical implications of germline mutations in a consecutive cohort of Chinese colorectal cancer (CRC) patients, providing insights that may inform population‐specific genetic testing strategies.
Liting Lu, Xinyu Peng, Jiaxin Zhang, Yixin Ding, Junliang Lu, Hengxue Lin, Huanwen Wu, Xicheng Wang, Yi Ba   +8 more
wiley   +1 more source

A Three‐Step Diagnostic Strategy for Malignant Pleural Effusions

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT New diagnostic tools, such as high fluorescence cells (HFc) and tumor markers (TMs), have emerged in the quest to accurately diagnose malignant pleural effusion (MPE). This study evaluated the diagnostic performance of the HFc and TMs combination.
Elisa Nuez‐Zaragoza, Vicente Aguadero, Indira Bhambi‐Blanco, Mònica Vidal‐Pla, Isabel Aparicio‐Calvente, M. Rosa Escoda‐Giralt, Joana Gallardo‐Campos, Joan Carles Ferreres, Luis Frisancho, Laia Mas‐Maresma, Patricia Aguilera‐Fernández, Sonia Marco‐Continente, Marina Sierra‐Boada, Pablo Andreu‐Cobo, Miquel Gallego, Francesca Canalias, Javier Hernando‐Redondo, Jaume Trapé   +17 more
wiley   +1 more source

TTK Overexpression: A Negative Prognostic Biomarker in Anaplastic Thyroid Carcinoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Given threonine and tyrosine kinase (TTK)'s oncogenic role in various cancers and its understudied status in thyroid cancer, this study investigates TTK expression in thyroid lesions to assess its diagnostic and therapeutic potential. Methods We analyzed differential TTK expression levels using public datasets (n = 143) and clinical
Yan Guo, Zhidong Sun, Xiao Liu, Xianni Liu, Haiwen Chen, Menglan Zhang, Weibo Mao, Yuan Cao   +7 more
wiley   +1 more source

Cancer Prevalence Among Large Cohort of Individuals With Down Syndrome: Implications for Screening Guidelines

Cancer Medicine, Volume 15, Issue 6, June 2026.
Individuals with Down syndrome have distinctive cancer profiles as compared with the general US population. Healthcare guidelines related to cancer screenings should reflect these unique profiles. ABSTRACT Introduction It is known that individuals with Down syndrome (DS) have a significantly different spectrum of malignancies and neoplasms.
Veronica Fitzpatrick, Akaninyene Noah, Anne Rivelli, Rachel Johnson, Melissa Zak, Joaquin Espinosa, Brian Chicoine   +6 more
wiley   +1 more source

SIRT1: Protean roles at the nexus of health, disease, and therapeutics

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
SIRT1 serves as a central regulator linking metabolism, stress responses, and disease. It influences diverse processes, including transcriptional and posttranscriptional gene expression and protein activity, inflammation, mitochondrial function, and cell survival, through the deacetylation of multiple protein targets. While SIRT1 often plays protective
Brahim Chaqour
wiley   +1 more source