Results 131 to 140 of about 39,716 (234)

Integrating antibody–drug conjugates into solid tumor oncology: Current standards and future directions

Cancer, Volume 132, Issue S1, 1 June 2026.
Abstract Antibody–drug conjugates (ADCs) represent a major advance in precision oncology, combining the selectivity of monoclonal antibodies with the cytotoxic potency of chemotherapy. By enabling targeted intracellular delivery of highly potent payloads, ADCs aim to maximize antitumor activity while minimizing systemic toxicity. This review summarizes
André Mansinho, Joana Albuquerque, Andreia Lopes, Emiliano Calvo   +3 more
wiley   +1 more source

The Role of the Mesopancreas in Pancreatic Neuroendocrine Neoplasms. [PDF]

J Clin Med
David SO, Sultani AB, Alexander A, Vaghiri S, Esposito I, Knoefel WT, Safi SA.   +6 more
europepmc   +1 more source

Metachronous Primary Pancreatic Neuroendocrine Tumor and Adenocarcinoma: A Case Report

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with most patients presenting with advanced disease. Surgical resection remains the only potentially curative option, yet recurrence rates are high. Case We present a rare case of metachronous primary pancreatic neuroendocrine tumor (PanNET) and PDAC in a 71‐year‐old ...
Anastasia S. Fatyanova, Maria E. Kalinina, Dina F. Islamova, Igor O. Shchekoturov, Julia V. Lerner, Nadezhda A. Stashevskaya, Pavel Burko, Ilias Miltiadis   +7 more
wiley   +1 more source

Commentary: "Venous thromboembolism following surgery for pancreatic neuroendocrine neoplasms". [PDF]

Res Pract Thromb Haemost
Merriman E.
europepmc   +1 more source

Sensing and Communicating β‐Cell Stress in the Context of T1D Etiology: New Opportunities for Therapeutic Impact

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Type 1 diabetes (T1D) results from the immune‐mediated destruction of insulin‐producing pancreatic β‐cells. Recent human studies show that early β‐cell stress maladaptations precede overt immune cell infiltration. DOC2B, a vesicle secretion regulatory protein that supports β‐cell functionality and resilience against stress, declines early in T1D ...
Diana Esparza, Chathurani S. Jayasena, Tijana Jovanovic‐Talisman, Debbie C. Thurmond   +3 more
wiley   +1 more source

Pancreatic Adenocarcinoma: Diagnosis by Ultrasound‐Guided Fine‐Needle Aspiration—Cyto‐Histological Correlation and Experience at a Multidisciplinary Tertiary Reference Center

Diagnostic Cytopathology, Volume 54, Issue 6, Page 403-416, June 2026.
ABSTRACT Background Pancreatic adenocarcinoma (PDAC) is characterized by its poor prognosis. Cytology is essential for diagnostic confirmation and ancillary studies. The endoscopic ultrasound (EUS) set a precedent, facilitating cytological sampling through fine‐needle aspiration (FNA), with a sensitivity of 93% and a specificity of 95%.
Judith González‐López, Mónica Elizabeth Bauza, Judith Pérez‐Rojas, Cecilia López‐Valdivia, Carlos Zac Romero, Óscar Castells‐Perona, Cristina Ballester‐Ibáñez, Eva Montalvá‐Orón, Rafael López‐Andújar, Lidia Argüello‐Viudez, Mireya Prieto Rodríguez   +10 more
wiley   +1 more source

Combined Detection of Preoperative Serum Calcitonin and Carcinoembryonic Antigen in Medullary Thyroid Carcinoma: A Retrospective Multicenter Cohort Study

Health Care Science, Volume 5, Issue 3, Page 223-230, June 2026.
Compared with the detection of either marker alone, the combined detection of calcitonin (Ctn) and carcinoembryonic antigen (CEA) improved the diagnostic accuracy for medullary thyroid cancer (MTC) but did not enhance the positive predictive value (PPV).
Yu Yang, Yufei He, Bo Lin, Yuanyuan Zheng, Xinyi Deng, Wenxin Chen, Zhenbang Ke, Yue Qiu, Yuting Hong, Jiayuan Zhang, Guojie Dong, Siqi Qiao, Ziyi Xin, Xuyang Li, Tianyi Xu, Wenke Chen, Xinwen Chen, Yingtong Hou, Fenghua Lai, Jianyan Long, Zhanqiang Zhang, Xiangdong Xu, Yihao Liu   +22 more
wiley   +1 more source

Peripheral vascular rim on endoscopic ultrasound as a practical rule-in sign for pancreatic neuroendocrine neoplasms. [PDF]

Clin Endosc
Cho E.
europepmc   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, Volume 2, Issue 2, Page 280-308, June 2026.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Predicting the Unpredictable: AI-Driven Prognosis in Pancreatic Neuroendocrine Neoplasms. [PDF]

Cancers (Basel)
Merola E, Pirino E, Marcucci S, Chierichetti F, Michielan A, Bernardoni L, Gabbrielli A, Dore MP, Fanciulli G, Brolese A.   +9 more
europepmc   +1 more source