Results 111 to 120 of about 1,457,192 (230)

Pancreatic neuroendocrine tumor: prediction of the tumor grade using magnetic resonance imaging findings and texture analysis with 3-T magnetic resonance

open access: yes, 2019
Chuan-gen Guo,1,* Shuai Ren,2,* Xiao Chen,2 Qi-dong Wang,1 Wen-bo Xiao,1 Jing-feng Zhang,1 Shao-feng Duan,3 Zhong-qiu Wang2 1Department of Radiology, The First Affiliated Hospital, College of Medicine Zhejiang University, Hangzhou 310003, China ...
Wang Q   +7 more
core  

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

open access: yesSmart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou   +4 more
wiley   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

open access: yesSmart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang   +5 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

open access: yesVIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Pancreatic Neuroendocrine Tumor Presenting as Acute Pancreatitis

open access: yes, 2018
We report a case of acute pancreatitis secondary to pancreatic neuroendocrine tumor. A 46-year old man presented with upper abdominal pain. The serum amylase and lipase were elevated.
Minjeong Kim   +7 more
core   +1 more source

Perioperative Outcomes of Patients With Pancreatic Neuroendocrine Neoplasms in the Context of Different Body Composition Phenotypes

open access: yesWorld Journal of Surgery, EarlyView.
Pancreatic neuroendocrine neoplasms (pNEN) are rare and heterogeneous tumors with increasing incidence. While surgical resection remains the only curative treatment, perioperative outcomes are influenced by patient‐related risk factors. Recent research highlights body composition (BC) as a prognostic marker in oncological and transplantation surgery ...
Fabiola A. Bechtiger   +12 more
wiley   +1 more source

Small Bowel Cancer: Implications of Preoperative Work‐Up on Surgical Strategy

open access: yesWorld Journal of Surgery, EarlyView.
Small bowel cancers comprise a heterogeneous group of malignancies, making diagnosis and treatment challenging. This study aimed to evaluate the ability of preoperative diagnostic work‐up to predict clinical and histopathological findings, facilitate subgroup identification, and support tailored, individualized surgical strategies. Preoperative work‐up
Erik Kjæstad   +4 more
wiley   +1 more source

Extended D3 Mesenterectomy in Small Bowel Cancer Treatment: Feasibility and Importance for Staging. First Results of a Prospective Clinical Trial

open access: yesWorld Journal of Surgery, EarlyView.
There is no consensus on surgical techniques in small bowel cancer, particularly regarding the extent of lymph node dissection and strategic choices according to tumor localization and histological type. Clearance of central lymph node metastases can be challenging, especially when small intestinal neuroendocrine tumor (siNET) metastases give rise to ...
Erik Kjæstad   +6 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Liver metastasis from pancreatic neuroendocrine tumor: A case report

open access: yes
BACKGROUND Pancreatic neuroendocrine neoplasms (pNENs) are rare tumors with a pathological spectrum ranging from well-differentiated tumors (pancreatic neuroendocrine tumors) to poorly differentiated carcinomas (pancreatic ...
Tao Wang   +4 more
core   +1 more source

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