Results 71 to 80 of about 1,842,584 (317)

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Infected Necrosis in Severe Pancreatitis - Combined Nonsurgical Multi-Drainage with Directed Transabdominal High-Volume Lavage in Critically Ill Patients [PDF]

, 2009
Background: Infection of pancreatic necrosis is a life-threatening complication during the course of acute pancreatitis. In critically ill patients, surgical or extended endoscopic interventions are associated with high morbidity and mortality. Minimally
Huber, W., Umgelter, A., Gaa, J., Prinz, C., Becker, V., Schmid, R. M., Bajbouj, M., Ludwig, L., Meining, Alexander, Becker, V.;Huber, W.;Meining, A.;Prinz, C.;Umgelter, A.;Ludwig, L.;Bajbouj, M.;Gaa, J.;Schmid, R. M., Becker, V;Huber, W;Meining, A;Prinz, C;Umgelter, A;Ludwig, L;Bajbouj, M;Gaa, J;Schmid, RM   +10 more
core   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

Advanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song, Yan‐Lai Tang, Xiaoting Liu, Jiayi Zheng, Chong Wu, Tang Li, Junhong Ye, Dianmin Xia, Yong Mei, Jingxuan Ma, Libin Huang, Xuequn Luo, Liheng Chen, Yanlin Qin, Weiling He   +14 more
wiley   +1 more source

Surgery in tropical pancreatitis

Journal of British Surgery, 1988
Abstract Nineteen consecutive patients with tropical pancreatitis and chronic pancreatic pain operated upon over a 3-year period in Kerala, India, are reported. The pancreatic ductal morphology was studied by ultrasound scan, endoscopic retrograde cholangiopancreatography and/or operative pancreatography. In 17 patients, duct drainage by
P G, Thomas, P, Augustine
openaire   +2 more sources

Hybrid Continuum Robot Designs and Architectures for Healthcare Applications

Advanced Robotics Research, EarlyView.
Hybrid continuum robots represent an emerging class of flexible manipulators that blend materials, structures, and actuation concepts from the established fields of soft and continuum robotics. This review introduces an accessible framework to distinguish key hybridization approaches, surveys current designs aimed at complex clinical applications, and ...
Burak Ozdemir, Muhammad A. Khalid, Manish Chauhan, Pietro Valdastri, James H. Chandler   +4 more
wiley   +1 more source

Role of tumor mutation burden-related signatures in the prognosis and immune microenvironment of pancreatic ductal adenocarcinoma

Cancer Cell International, 2021
Background High tumor mutation burden (TMB) has gradually become a sensitive biomarker for predicting the response to immunotherapy in many cancers, including lung, bladder and head and neck cancers.
Rong Tang, Xiaomeng Liu, Wei Wang, Jie Hua, Jin Xu, Chen Liang, Qingcai Meng, Jiang Liu, Bo Zhang, Xianjun Yu, Si Shi   +10 more
doaj   +1 more source

Nationwide prospective audit of pancreatic surgery: design, accuracy, and outcomes of the Dutch Pancreatic Cancer Audit [PDF]

, 2017
Item does not contain fulltextBACKGROUND: Auditing is an important tool to identify practice variation and 'best practices'. The Dutch Pancreatic Cancer Audit is mandatory in all 18 Dutch centers for pancreatic surgery.
Jong, K.P. de, Zwart, MJ, Besselink, M.G., van Eijck, Casper, Patijn, GA, Scheepers, J.J., Busch, O.R., Molenaar, IQ, van der Schelling, GP, de Jong, KP, Rijssen, L.B. van, Santvoort, H.C. van, Laarhoven, C.J. van, Bosscha, K, Kazemier, G., Groot Koerkamp, B; id_orcid, Klaase, J, Molenaar, I.Q., Kazemier, G, Rupert, CG, Scheepers, JJ, Klaase, J., van Rijssen, LB, Dutch Pancreatic Canc Grp, Bonsing, B.A., Dam, R.M. van, Eijck, C.H. van, Bonsing, BA, de Hingh, IH, Busch, OR, Gerhards, MF, Groot Koerkamp, B, van der Harst, E (Erwin), Harst, E. van der, Laarhoven, C.J.H.M. van, van Dam, RM, Zwart, M.J., Hingh, I.H. de, Gerhards, M.F., Patijn, G.A., Besselink, MG, Koerkamp, B.G., Bosscha, K., Schelling, G.P. van der, van Santvoort, HC, Rupert, C.G., van Laarhoven, CJ   +46 more
core   +1 more source

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Nationwide evaluation of pancreatic cancer networks ten years after the centralization of pancreatic surgery [PDF]

, 2023
Background: Due to centralization of pancreatic surgery, patients with pancreatic cancer are treated in pancreatic cancer networks, composed of referring hospitals (Spokes) and an expert center (Hub).
Dutch Pancreatic Cancer Group
core  

Continuum Robots in Surgery: From Engineering Design to Clinical Practice

Advanced Robotics Research, EarlyView.
The hyper‐redundant nature of continuum robot structures enables near‐infinite degrees of freedom leading to immense potential for medical applications. This review provides a historical background of continuum robots and novel ideas shaping their progress to current structural design, sensing technology, modeling techniques, and control methods.
Griffin Smith, Kaitlyn Clancy, Siwen Xie, Xiaochen Li, Sarah Khalife, Benjamin van der Woerd, Onaizah Onaizah   +6 more
wiley   +1 more source