Results 151 to 160 of about 1,729,239 (300)

Single-Cell Glycomics of the Pancreatic Tumor Microenvironment: Technologies, Glyco-Immune Checkpoints, and Tumor-Immune Communication. [PDF]

Adv Biol (Weinh)
Anh DXT, Tateno H.
europepmc   +1 more source

Pancreatic Tumors

, 1980
La utilización de nuevos procedimientos de estudio permite actualmente el diagnóstico preoperatorioen un porcentaje altísimo de casos. Pero el diagnóstico precoz del cáncer de páncreas no se ha logrado, no pudiéndore aún detectar tumore, de pequeño tamaño.
Delgado, Bolívar, Etala, Emilio, Mainetti, José M, Piacenza, Guillermo, Torterolo, Edgardo, Vercelli, Jorge   +5 more
openaire   +1 more source

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

A Rare Case of Solid Pseudopapillary Pancreatic Tumor Causing Abdominal Pain. [PDF]

J Emerg Trauma Shock
Ryu A, Kasparov E, Scanameo A, Yanes D, Garra G, Lee CC.   +5 more
europepmc   +1 more source

Pancreatic Schwannoma: A Rare Pancreatic Tumor

Internal Medicine, 2020
Iwano, Kosuke, Kurita, Akira, Azuma, Shunjiro, Yazumi, Shujiro   +3 more
openaire   +3 more sources

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

Advanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen, Xin Liu, Gaoran Ge, Li Xu, Ziyu Zhang, Chang Lv, Hao Xu, Wenhao Li, Yi Qin, Qifeng Sheng, Qihan Wang, Hongxia Li, Jun Zhou, Huilin Yang, Dechun Geng   +14 more
wiley   +1 more source

Stromal homeostasis-restoring "rocket-like" nanomedicine inhibited pancreatic tumor growth in vivo. [PDF]

Mater Today Bio
Fu N, Qin K, Li D, Zhu M, Jiang Y, Liu W, Jin J.   +6 more
europepmc   +1 more source

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

Advanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo, Yang Zhao, Xianle Rong, Xingyu Chen, Xiao Wang, Tianyi Liu, Yunfei Xie, Yushu Zou, Pingsen Zhao, Qiang Liu, Fuping You   +10 more
wiley   +1 more source

Effects of Proglumide with Chemotherapy on the Pancreatic Tumor Microenvironment: Phase 1 PROGEM Trial. [PDF]

Pharmaceutics
Smith JP, Nkulikiyimana GC, Cao H, Chen W, Kallakury B, Kwagyan J, Duttargi A, Weinberg BA.   +7 more
europepmc   +1 more source

Corynoxine Inhibits Tumor Growth via Targeting NQO1 and Modulating the PTPA–NQO1/PP2A Switch to Activate PP2A

Advanced Science, EarlyView.
Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou, Li Lin, Mengjie Xia, Ruohan Liang, Yueyue Zhang, Linna Du, Xuan Cao   +6 more
wiley   +1 more source