Results 71 to 80 of about 1,718,006 (300)

Pancreatic tumors imaging: An update

International Journal of Surgery, 2016
Currently, ultrasound (US), computed tomography (CT) and Magnetic Resonance imaging (MRI) represent the mainstay in the evaluation of pancreatic solid and cystic tumors affecting pancreas in 80-85% and 10-15% of the cases respectively. Integration of US, CT or MR imaging is essential for an accurate assessment of pancreatic parenchyma, ducts and ...
Scialpi, Michele, REGINELLI, Alfonso, D'Andrea, Alfredo, Gravante, Sabrina, Falcone, Giuseppe, Baccari, Paolo, Manganaro, Lucia, Palumbo, Barbara, CAPPABIANCA, Salvatore   +8 more
openaire   +3 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

m6A-dependent translation of circPICALM encodes a novel metastasis-promoting oncoprotein in intrahepatic cholangiocarcinoma

Molecular Cancer
Background Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive liver cancer with a poor prognosis and rapid metastatic potential. Although circular RNAs (circRNAs) have emerged as important regulators in cancer biology, their translational ...
Hui Li, Sheng Wang, Fengsheng Dai, Hailing Liu, Cheng Zhang, Maoyun Liu, Yi Wang, Lei Xiang, Xi Zhang, Ai Shen, Yu Wang, Nan Wu, Huiping Zhou, Genshu Wang, Yongzhong Wu, Dewei Li   +15 more
doaj   +1 more source

A completeness-independent method for pre-selection of closely related genomes for species delineation in prokaryotes

BMC Genomics, 2020
Background Whole-genome approaches are widely preferred for species delineation in prokaryotes. However, these methods require pairwise alignments and calculations at the whole-genome level and thus are computationally intensive. To address this problem,
Yizhuang Zhou, Jifang Zheng, Yepeng Wu, Wenting Zhang, Junfei Jin   +4 more
doaj   +1 more source

Tumor Microenvironment in Pancreatic Intraepithelial Neoplasia

, 2021
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive tumors with a poor prognosis. A characteristic of PDAC is the formation of an immunosuppressive tumor microenvironment (TME) that facilitates bypassing of the immune surveillance.
Friederike V. Opitz, Lena Haeberle, Irene Esposito, Alexandra Daum   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A case of pancreatic hamartoma pathologically confirmed after robot-assisted pancreaticoduodenectomy [PDF]

, 2019
Pancreatic hamartoma is a rare benign tumor that can be easily misdiagnosed due to its rarity. Its diagnostic ambiguity demands surgical resection for confirmation.
황호경, 노승윤, 강창무, 이우정   +3 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Challenges and hope: latest research trends in the clinical treatment and prognosis of liposarcoma

Frontiers in Pharmacology
Liposarcoma, as a complex disease, is characterized by intricate interactions between distinct histopathological subtypes and corresponding clinical outcomes, emphasizing the necessity of personalized approaches in diagnosis and treatment strategies ...
Hongliang Liu, Xi Wang, Xiaoyu Wang, Fabo Qiu, Bin Zhou   +4 more
doaj   +1 more source