Results 91 to 100 of about 1,718,006 (300)

Irreversible Electroporation of Pancreatic Tumors

, 2017
Over 95% of pancreatic cancers are exocrine tumors that bare a dismal prognosis. Although oncological outcome is best for patients presenting with nonmetastatic resectable disease, cure is rarely achieved [1]. Up to 40% of patients present with nonmetastatic disease that is considered unresectable due to vascular encasement (locally advanced pancreatic
Meijerink, Martijn R., Nilsson, Anders, Narayanan, Govindarajan, Martin, Robert   +3 more
openaire   +4 more sources

A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer [PDF]

, 2006
Background Anti-angiogenic treatment is believed to have at least cystostatic effects in highly vascularized tumours like pancreatic cancer. In this study, the treatment effects of the angiogenesis inhibitor Cilengitide and gemcitabine were compared with
Castellano Daniel, Kleeff Jörg, Vermorken Jan, Albert Abad Esteve, Simon van Belle, CASTELLANO, D, STOGER, H, Esteve, Albert Abad, Jochen Raedle, HERZOG, P, DAVIDSON, N, OETTLE, H, Balcke, Peter, SCHEITHAUER, W, DOBROWOLSKI, F, TEMPIA-CALIERA, AA, Neville Davidson, Langrehr, Jan M., Herzog Peter, Scheithauer Werner, Friess Helmut, HOSSFELD, DK, KOVAR, A, Herbert Stöger, Adrien A Tempia-Caliera, Jan M Langrehr, Neyns Bart, Bart Neyns, Castellano, Daniel, Oettle Helmut, Herzog, Peter, BALCKE, P, Dittrich, Christian, KATZ, F, Katz Frieder, Robert Hawkins, Hawkins Robert, Raedle, Jochen, PIEDBOIS, P, LANGREHR, JM, Pascal Piedbois, Werner Scheithauer, Dobrowolski, Frank, NIEDERGETHMANN, M, Nippgen Johannes, Hawkins, Robert, Van Belle, Simon, Piedbois Pascal, Raedle Jochen, Andreas Kovar, RAEDLE, J, HAWKINS, R, Stöger Herbert, Peter Balcke, Davidson, Neville, Tempia-Caliera, Adrien A., DITTRICH, C, Christian Dittrich, Hossfeld Dieter K, Tempia-Caliera Adrien A, Helmut Oettle, NIPPGEN, J, Esteve Albert, ESTEVE, AA, Balcke Peter, Friess, Helmut, Katz, Frieder, Oettle, Helmut, Hossfeld, Dieter K., Dobrowolski Frank, Peter Herzog, Daniel Castellano, Kleeff, Jörg, Niedergethmann Marco, Marco Niedergethmann, Dieter K Hossfeld, Jan Vermorken, Scheithauer, Werner, KLEEFF, J, Helmut Friess, Nippgen, Johannes, NEYNS, B, Jörg Kleeff, Dittrich Christian, Langrehr Jan M, Davidson Neville, Stöger, Herbert, Frank Dobrowolski, Frieder Katz, Kovar, Andreas, Johannes Nippgen, van Belle Simon, Niedergethmann, Marco, Vermorken, Jan, Kovar Andreas, FRIESS, H, Piedbois, Pascal, Neyns, Bart, VERMORKEN, J, Stoeger, Herbert, [et al.]   +100 more
core   +2 more sources

Bio‐Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment

Advanced Functional Materials, EarlyView.
A bio‐inspired biopolymeric implantable drug delivery platform enables localized and sustained release of 7‐ethyl‐10‐hydroxycamptothecin (SN‐38) in solid tumor treatment. The three‐dimensional (3D) structured crosslinked‐chitosan implants are fabricated via 3D‐printed molds and provide drug release over 3 months, significantly inhibiting tumor growth ...
Mercedes Lozano‐Garcia, Constantine Vogiatzis, Alejandra Planells‐Devesa, Emre Dikici, Caroline Vieira Maluf, Vasudev Vivekanand Nayak, Paulo G. Coelho, Lukasz Witek, Alicia Bilbao, Daniel Bilbao, Prasoon Mohan, Sapna Deo, Sylvia Daunert   +12 more
wiley   +1 more source

Integrating intratumoral, peritumoral, and clinical features in an ultrasound-based radiomics model: contributions and synergies for predicting microvascular invasion in hepatocellular carcinoma

Frontiers in Oncology
BackgroundMicrovascular invasion (MVI) is a critical determinant of poor prognosis in hepatocellular carcinoma (HCC). Accurate preoperative prediction of MVI is essential for optimizing surgical and therapeutic strategies.
Hong Fu, Hong Fu, Yanhua Huang, Baochun Lu, Baochun Lu, Jianhua Yu, Jianhua Yu, Difan Zhou, Difan Zhou, Chuanling Hou, Luohang Xu, Hongwei Qian, Hongwei Qian   +12 more
doaj   +1 more source

Tumors of the pancreatic islets [PDF]

Cancer, 1960
J, SIERACKI, R B, MARSHALL, R C, HORN
openaire   +2 more sources

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Efficacy and conversion outcome of chemotherapy combined with PD-1 inhibitor for patients with unresectable or recurrent gallbladder carcinoma: a real-world exploratory study

World Journal of Surgical Oncology
Background Gallbladder carcinoma (GBC) is an extremely aggressive tumor of the biliary tract with a bleak prognosis, and the evidence supporting the benefit of available systemic therapy for advanced GBC is scarce.
Qin-qin Liu, Jian Yan, Yan-fang Ye, Cai-ni Yang, Zhi-jun Chen, Hao-ming Lin, Zi-tong Zhang, Rui Zhang   +7 more
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Diabetes mellitus associated with pancreatic somatostatin tumor: A case report

Journal of Clinical and Translational Endocrinology Case Reports, 2016
The finding of diabetes in association with a pancreatic neuroendocrine tumor (PNET) in patients is uncommon. Here, we describe a 74-year-old diabetes patient with a tumor in the pancreatic head.
Bing Han, MD, Hualin Zhai, MD, Jiao Yu, MD, Fangzhen Xia, MD, Yingli Lu, MD   +4 more
doaj   +1 more source

Diabetes and the risk of pancreatic cancer.

, 1994
BACKGROUND: Diabetes and pancreatic cancer are known to be associated, but the cause of the association and whether diabetes is a risk factor for pancreatic cancer remain controversial.
Morselli Labate AM, PASQUALI, CLAUDIO, Italian Pancreatic Cancer Study Group, Gullo L, Pezzilli R, SPERTI, COSIMO   +5 more
core   +1 more source