Results 11 to 20 of about 10,562 (173)

Comparative study of protease hydrolysis reaction demonstrating Normalized Peptide Bond Cleavage Frequency and Protease Substrate Broadness Index.

open access: yesPLoS ONE, 2020
Two commercial proteases (subtilisin-typed FNA from Bacillus amyloliquefaciens, and chymotrypsin-like NPP from Nocardiopsis prasina), porcine pepsin, porcine pancreatin having protease activity and their combinations were studied in vitro by LC-MS for ...
Shukun Yu   +2 more
doaj   +1 more source

The effectiveness of pancreatic enzyme replacement therapy using microencapsulated pancreatin preparations in the correction of nutritional status in patients with chronic pancreatitis: a prospective observational study [PDF]

open access: yesТерапевтический архив, 2020
Aim. The goal is to evaluate the effectiveness of pancreatic enzyme replacement therapy (PERT) using microencapsulated pancreatin preparations for the correction of nutritional status in patients with chronic pancreatitis (CP) and associated exocrine ...
T V Bideeva   +7 more
doaj   +1 more source

Nanostructured Lipid Carriers (NLCs) for Oral Peptide Drug Delivery: About the Impact of Surface Decoration

open access: yesPharmaceutics, 2021
This study was aimed to evaluate the impact of surfactants used for nanostructured lipid carriers (NLCs) to provide enzymatic protection for incorporated peptides.
Iram Shahzadi   +3 more
doaj   +1 more source

Exploring the DPP-IV Inhibitory, Antioxidant and Antibacterial Potential of Ovine “Scotta” Hydrolysates

open access: yesFoods, 2021
The aim of this work was to valorize the by-product derived from the ricotta cheese process (scotta). In this study, ovine scotta was concentrated by ultrafiltration and then subjected to enzymatic hydrolyses using proteases of both vegetable (4% E:S, 4 ...
Roberto Cabizza   +7 more
doaj   +1 more source

Investigating the Effect of Protease Enzyme Type and Hydrolysis Time on the Antioxidant Properties of Flaxseed Meal (Linum usitatissimum) Protein Hydrolysates [PDF]

open access: yesمجله پژوهش‌های علوم و صنایع غذایی ایران
In this research, the effect of protease enzyme type (pepsin and pancreatin) and hydrolysis time (40-200 minutes) on the degree of hydrolysis and antioxidant properties (DPPH radical scavenging activity, Fe chelating activity, Fe reducing power and total
Maryam Hashemi   +2 more
doaj   +1 more source

Pancreatic exocrine insufficiency in diabetes mellitus

open access: yesСахарный диабет, 2023
Diabetes is disease of both the endo- and exocrine parts of the pancreas. Pancreatic exocrine insufficiency (PEI) can occur in every 2–3 patients with diabetes and affect not only the quality, but also life expectancy. At the same time, the diagnosis and
M. V. Shestakova   +10 more
doaj   +1 more source

Enzymatic hydrolysis of grass carp myofibrillar protein and antioxidant properties of hydrolysates

open access: yesCzech Journal of Food Sciences, 2010
Myofibrillar protein was extracted from grass carp, a freshwater fish, and hydrolysed using five commercial proteases (papain, pancreatin 6.0, bromelain, Neutrase 1.5MG, and Alcalase 2.4 L). The antioxidant activities of the hydrolysates were determined.
Jiaoyan Ren   +4 more
doaj   +1 more source

The effect of enzymes on the in vitro degradation behavior of Mg alloy wires in simulated gastric fluid and intestinal fluid

open access: yesBioactive Materials, 2022
With an upsurge of biodegradable metal implants, the research and application of Mg alloys in the gastrointestinal environment of the digestive tract have been of great interest. Digestive enzymes, mainly pepsin in the stomach and pancreatin in the small
Yue Zhang   +7 more
doaj   +1 more source

Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery

open access: yesAngewandte Chemie, EarlyView.
We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne   +5 more
wiley   +2 more sources

Malnutrition and the Ways of its Correction in Infants with Food Intolerance

open access: yesZdorovʹe Rebenka, 2016
Objective: to examine the status of digestion and the efficiency of correction of its disorders in infants with food intolerance. Patients and methods. We observed 40 infants (from 6 months to 3 years of life) with food intolerance, including 14 children
O.H. Shadrin   +2 more
doaj   +1 more source

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