Results 41 to 50 of about 12,946 (160)

Impact of the pancreatic enzyme replacement therapy (PERT) shortage on prescribing in England: Analysis of national data

British Journal of Clinical Pharmacology, EarlyView.
Aim Pancreatic enzyme replacement therapy (PERT) is essential for the management of pancreatic exocrine insufficiency. Since June 2023, the United Kingdom has been affected by a global shortage of PERT. We investigated the impact of this shortage on national prescribing trends for Creon, Nutrizym, Pancrex and Pangrol.
Teena S. Varghese, Mary E. Phillips, Louis Fisher, Helen Fitt, Adam Frampton, Christopher Wood, Agnieszka Lemanska   +6 more
wiley   +1 more source

Submandibular salivary gland enlargement by feeding pancreatin to rats

, 1963
Addition of pancreatin, a dried and defatted preparation of porcine pancreas, to the diet of rats resulted in a marked increase in both the fresh and dry weights of the submandibular salivary glands. A range of pancreatin doses, from 0.25 to 4% resulted
Edward F. Voelkel, Herbert Wells
core   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

INFOGEST 2.0 Digestion Method: Characterization of the Sterol Content in the Digestion Reagents

Biology and Life Sciences Forum, 2021
The INFOGEST digestion method was adapted for the evaluation of sterol bioaccessibility in a plant sterol (PS)-enriched beverage [1]. Recent modifications of the method, such as the addition of gastric lipase and cholesterol esterase, showed that the ...
Manuel Muñoz-Checa, Mussa Makran, Gabriel López-García, Antonio Cilla, Reyes Barberá, Amparo Alegría, Guadalupe García-Llatas   +6 more
doaj   +1 more source

Probiotic spore‐based bioresponsive drug delivery for reversing inflammatory bowel disease and its associated anxiety and depression

BMEMat, EarlyView.
A probiotic spore‐based drug delivery system (BCS‐Que@ApNPs) provides excellent targeted delivery, bioresponsive drug release, and long‐term retention (over 48 h), making it suitable for oral treatment of inflammatory bowel disease and its associated anxiety and depression.
Qingling Song, Beiyang Xue, Yao Li, Chuangxi Zhou, Junfei Yang, Yunfei Li, Lingwen Ding, Yun Zhang, Hongjuan Zhao, Lei Wang   +9 more
wiley   +1 more source

Differential sensitivity to SHH signaling and neural crest‐mediated Gas1 expression regulate jaw size during development and evolution

Developmental Dynamics, EarlyView.
Abstract Background Developmental control of jaw size is crucial to prevent birth defects and facilitate evolutionary adaptation. We have shown that jaw size is established by neural crest mesenchyme (NCM), which are progenitor cells that migrate into the mandibular primordia and produce the jaws.
Zuzana Vavrušová, Daniel B. Chu, An Nguyen, Yeniko Ta, Jennifer L. Fish, Richard A. Schneider   +5 more
wiley   +1 more source

Characterization and stabilization of pancreatin

, 2012
This work focuses on a study of enzyme mixture pancreatin, its characterization and subsequent encapsulation into liposomes. As a reference proteins bovine serum albumin and trypsin were used. Characterization of pancreatin consisted of two parts.
Wurstová, Agáta
core   +1 more source

Antioxidant Activity of Hydrolysates Prepared from Flaxseed Cake Proteins Using Pancreatin

Polish Journal of Food and Nutrition Sciences, 2014
Proteins were isolated from defatted flaxseed cake and hydrolysed with pancreatin. The hydrolysis process was conducted at a stable temperature of 50°C and pH 7.5, and monitored with the pH-stat method.
Karamać Magdalena, Kulczyk Anna, Sulewska Katarzyna   +2 more
doaj   +1 more source

Digestion‐Stage Structural Evolution and In Vitro Colonic Fermentation of Intestinally Undigested Residues From Tiger Nut Starch‐Fatty Acid Complexes

Food Bioengineering, EarlyView.
Tiger nut starch–fatty acid complexes show distinct structural evolution during digestion, while their intestinal residues display differential SCFA production and microbiota composition during in vitro colonic fermentation. ABSTRACT Starch‐fatty acid complexes can generate intestinally undigested material that subsequently enters colonic fermentation,
Hanwei Deng, Yi Zhao, Guandi Chen, Wendi Liu, Wenhao Li, Hongbin Wu, Fuhong Dai, Xiaoyan Ma, Changqing Wei   +8 more
wiley   +1 more source

Effects of enzyme type and process time on hydrolysis degree, electrophoresis bands and antioxidant properties of hydrolyzed proteins derived from defatted Bunium persicum Bioss. press cake

Heliyon, 2020
The present study aimed at investigating the effect of enzymatic hydrolysis times (40-240 min) with alcalase and pancreatin in enzyme-substrate ratio (2% w/w) on the hydrolysis degree, electrophoresis bands, antioxidant properties and chelating ...
Zahra Shahi, Seyyedeh Zahra Sayyed-Alangi, Leila Najafian   +2 more
doaj   +1 more source