Results 51 to 60 of about 451,014 (336)

An Endoscopic Transluminal Approach, Compared With Minimally Invasive Surgery, Reduces Complications and Costs for Patients With Necrotizing Pancreatitis.

Gastroenterology, 2019
BACKGROUND & AIMS Infected necrotizing pancreatitis is a highly morbid disease with poor outcomes. Intervention strategies have progressed from open necrosectomy to minimally invasive approaches.
J. Bang, J. P. Arnoletti, Bronte A. Holt, Bryce Sutton, M. Hasan, U. Navaneethan, N. Feranec, C. Wilcox, B. Tharian, R. Hawes, S. Varadarajulu   +10 more
semanticscholar   +1 more source

Time-Course Lipidomics of Ornithine-Induced Severe Acute Pancreatitis Model Reveals the Free Fatty Acids Centered Lipids Dysregulation Characteristics

Metabolites, 2023
The relationship between the type and intensities of lipids of blood and pancreas and the pathological changes in the pancreas during severe acute pancreatitis (SAP) remains unclear.
Jinxi Yang, Manjiangcuo Wang, Qi Qiu, Yan Huang, Yiqin Wang, Qianlun Pu, Na Jiang, Rui Wang, Li Wen, Xiaoying Zhang, Chenxia Han, Dan Du   +11 more
doaj   +1 more source

Infected Necrosis in Severe Pancreatitis - Combined Nonsurgical Multi-Drainage with Directed Transabdominal High-Volume Lavage in Critically Ill Patients [PDF]

, 2009
Background: Infection of pancreatic necrosis is a life-threatening complication during the course of acute pancreatitis. In critically ill patients, surgical or extended endoscopic interventions are associated with high morbidity and mortality. Minimally
A. Meining, A. Umgelter, Baron, Beger, Bradley, Bradley, Branum, C. Prinz, Connor, Connor, Dellinger, Fernandez-del Castillo, Hartwig, Isenmann, J. Gaa, L. Ludwig, M. Bajbouj, McKay, Nathens, Nordback, R.M. Schmid, Sand, Sarr, Seewald, Seifert, Seifert, Tsiotos, Tzovaras, V. Becker, W. Huber, Werner, Whitcomb   +31 more
core   +1 more source

Genetics, Cell Biology, and Pathophysiology of Pancreatitis.

Gastroenterology, 2019
Since the discovery of the first trypsinogen mutation in families with hereditary pancreatitis, pancreatic genetics has made rapid progress. The identification of mutations in genes involved in the digestive protease-antiprotease pathway has lent ...
J. Mayerle, M. Sendler, E. Hegyi, G. Beyer, M. Lerch, M. Sahin-Tóth   +5 more
semanticscholar   +1 more source

NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-inflammatory Response Syndromes in Mice With Acute Pancreatitis.

Gastroenterology, 2019
BACKGROUND & AIMS Pancreatitis starts with primarily sterile local inflammation that induces systemic inflammatory response syndrome (SIRS) followed by compensatory anti-inflammatory response syndrome (CARS). We investigated mechanisms of these processes
M. Sendler, Cindy van den Brandt, J. Glaubitz, A. Wilden, J. Golchert, F. Weiss, G. Homuth, Laura L. de Freitas Chama, N. Mishra, U. Mahajan, L. Bossaller, U. Völker, B. Bröker, J. Mayerle, M. Lerch   +14 more
semanticscholar   +1 more source

Identification of mitophagy-related biomarkers in severe acute pancreatitis: integration of WGCNA, machine learning algorithms and scRNA-seq

Frontiers in Immunology
BackgroundMitophagy is a highly conserved cellular process in eukaryotic cells that selectively clears dysfunctional or damaged mitochondria through autophagy mechanisms to maintain mitochondrial homeostasis.
Xiaozhou Xie, Xiaozhou Xie, Zheng Wang, Zheng Wang, Haoyu Zhang, Haoyu Zhang, Jiongdi Lu, Jiongdi Lu, Feng Cao, Feng Cao, Fei Li, Fei Li   +11 more
doaj   +1 more source

Staging chronic pancreatitis with exocrine function tests: Are we better? [PDF]

, 2017
Chronic pancreatitis (CP) is an inflammatory disease of the pancreas evolving in progressive fibrotic disruption of the gland with exocrine and endocrine pancreatic insufficiency.
MOLETTA, LUCIA, SPERTI, COSIMO
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Multifocal High-Grade Pancreatic Precursor Lesions: A Case Series and Management Recommendations [PDF]

, 2019
Background: The risk of developing invasive cancer in the remnant pancreas after resection of multifocal high-grade pancreatic precursor lesions is not well known.
Carr, Rosalie A., Roch, Alexandra M., Schmidt, Christian Max, Soufi, Mazhar, Wu, Howard H., Yip-Schneider, Michele T.   +5 more
core   +1 more source

Extracorporeal Catalytic Hemoperfusion Therapy for Refractory Septic Shock Using Ceria Nanoparticle‐Embedded Porous Microbeads

Advanced Functional Materials, EarlyView.
This study introduces an extracorporeal hemoperfusion system incorporating porous microbeads embedded with autocatalytic ceria nanoparticles (CeNPs) for targeted reactive oxygen species (ROS) scavenging in septic shock. The blood‐compatible hemoperfusion cartridge demonstrated significant improvements in survival, hemodynamic stability, and organ ...
Pilseon Im, Han‐Gil Jeong, Donghee Kim, Jimin Song, Ngoc Man Phan, Eun‐seo Choi, Young‐Min Kim, Seo‐Hyeon Jeong, Jooho Park, Inwon Park, Jaeyun Kim   +10 more
wiley   +1 more source