Results 61 to 70 of about 451,014 (336)

Hemoconcentration is associated with early faster fluid rate and increased risk of persistent organ failure in acute pancreatitis patients

JGH Open, 2020
Background Controversies existed surrounding the use of hematocrit to guide early fluid therapy in acute pancreatitis (AP). The association between hematocrit, early fluid therapy, and clinical outcomes in ward AP patients needs to be investigated ...
Tao Jin, Lan Li, Lihui Deng, Si Wen, Ruwen Zhang, Na Shi, Ping Zhu, Lan Lan, Ziqi Lin, Kun Jiang, Jia Guo, Tingting Liu, Anthony Philips, Xiaonan Yang, Vikesh K Singh, Robert Sutton, John A Windsor, Wei Huang, Qing Xia   +18 more
doaj   +1 more source

Role of Seipin in Human Diseases and Experimental Animal Models

Biomolecules, 2022
Seipin, a protein encoded by the Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2) gene, is famous for its key role in the biogenesis of lipid droplets and type 2 congenital generalised lipodystrophy (CGL2). BSCL2 gene mutations result in genetic
Yuying Li, Xinmin Yang, Linrui Peng, Qing Xia, Yuwei Zhang, Wei Huang, Tingting Liu, Da Jia   +7 more
doaj   +1 more source

Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus [PDF]

, 2016
Although there are high survival rates for children with acute lymphoblastic leukaemia, their outcome is often counterbalanced by the burden of toxic effects.
Attarbaschi, Andishe, Barzilai, Shlomit, Escherich, Gabriele, Frandsen, Thomas Leth, Halsey, Christina, Hough, Rachael, Jeha, Sima, Kato, Motohiro, Liang, Der-Cherng, Mikkelsen, Torben Stamm, Moricke, Anja, Niinimaki, Riitta, Piette, Caroline, Putti, Maria Caterina, Raetz, Elizabeth, Schmiegelow, Kjeld, Silverman, Lewis B., Skinner, Roderick, Tuckuviene, Ruta, van der Sluis, Inge, Zapotocka, Ester   +20 more
core   +2 more sources

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

Frontiers in Physiology, 2019
Pancreatic acinar cells require high rates of amino acid uptake for digestive enzyme synthesis, but excessive concentrations can trigger acute pancreatitis (AP) by mechanisms that are not well understood.
Xiaoying Zhang, Xiaoying Zhang, Tao Jin, Tao Jin, Na Shi, Linbo Yao, Xinmin Yang, Chenxia Han, Li Wen, Dan Du, Peter Szatmary, Rajarshi Mukherjee, Tingting Liu, Qing Xia, David N. Criddle, Wei Huang, Michael Chvanov, Robert Sutton   +17 more
doaj   +1 more source

Unclassified autoimmune pancreatitis mimicking pancreatic cancer [PDF]

, 2019
A 24-year-old black male presented with a 1-week obstructive jaundice and intermittent abdominal pain, with no significant weight loss and an unsuspicious abdominal exam.
Alves, A, Marinho, R, Nunes, V, Pignatelli, N   +3 more
core   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Yinchenhao Decoction Protects Against Acute Liver Injury in Mice With Biliary Acute Pancreatitis by Regulating the Gut Microflora–Bile Acids–Liver Axis

Gastroenterology Research and Practice
Conclusions: These findings imply a potential link between gut microbiota dysbiosis and intrahepatic cholestasis in BAP-ALI mice and suggest that YCHD treatment may confer protection against BAP-ALI via the gut microflora–bile acids–liver axis.
Xianlin Zhao, Xiajia Wu, Qian Hu, Jiaqi Yao, Yue Yang, Meihua Wan, Wenfu Tang   +6 more
doaj   +1 more source

Targeting Macrophage Migration Inhibitory Factor in Acute Pancreatitis and Pancreatic Cancer

Frontiers in Pharmacology, 2021
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine implicated in the pathogenesis of inflammation and cancer. It is produced by various cells and circulating MIF has been identified as a biomarker for a range of diseases ...
Yongjian Wen, Yongjian Wen, Yongjian Wen, Wenhao Cai, Wenhao Cai, Jingyu Yang, Xianghui Fu, Lohitha Putha, Qing Xia, John A. Windsor, Anthony R. Phillips, Anthony R. Phillips, Joel D. A. Tyndall, Dan Du, Tingting Liu, Wei Huang, Wei Huang   +16 more
doaj   +1 more source

Intra-abdominal hypertension and abdominal compartment syndrome in pancreatitis, paediatrics, and trauma [PDF]

, 2015
Intra-abdominal hypertension (IAH) is an important contributor to early organ dysfunction in trauma and sepsis. However, relatively little is known about the impact of intra-abdominal pressure (IAP) in general internal medicine, pregnant patients, and ...
De Keulenaer, Bart L, De laet, Inneke, De Waele, Jan, Ejike, Janeth C, Ivatury, Rao, Kimball, Edward, Kirkpatrick, Andrew W, Leppäniemi, Ari, Malbrain, Manu LNG, Roberts, Derek J   +9 more
core   +1 more source