Results 71 to 80 of about 198,132 (219)

Activation of pancreatic stellate cells attenuates intracellular Ca2+ signals due to downregulation of TRPA1 and protects against cell death induced by alcohol metabolites

Cell Death and Disease, 2022
Alcohol abuse, an increasing problem in developed societies, is one of the leading causes of acute and chronic pancreatitis. Alcoholic pancreatitis is often associated with fibrosis mediated by activated pancreatic stellate cells (PSCs). Alcohol toxicity
Agnieszka A. Kusiak, Monika A. Jakubowska, Kinga B. Stopa, Xiaoying Zhang, Wei Huang, Julia V. Gerasimenko, Oleg V. Gerasimenko, Robert Sutton, Ole H. Petersen, Pawel E. Ferdek   +9 more
doaj   +1 more source

Pancreatic complications following orthotopic liver transplantation [PDF]

, 1992
During fiscal year 1986, 40 out of 196 patients (21%) developed hyperamylasemia following orthotopic liver transplantation. The placement of a retropancreatic aortohepatic arterial interposition graft was associated with hyperamylasemia (p < 0.025 ...
Gordon, RD, Iwatsuki, S, Makowka, L, Marsh, JW, Shimada, M, Starzi, TE, Stieber, AC, Todo, S, Tzakis, AG, Yanaga, K   +9 more
core  

Quality of Life in Chronic Pancreatitis is Determined by Constant Pain, Disability/Unemployment, Current Smoking, and Associated Co-Morbidities [PDF]

, 2017
OBJECTIVES: Chronic pancreatitis (CP) has a profound independent effect on quality of life (QOL). Our aim was to identify factors that impact the QOL in CP patients.
Abberbock, Judah, Alkaade, Samer, Amann, Stephen T., Anderson, Michelle A., Baillie, John, Banks, Peter A., Brand, Randall E., Conwell, Darwin L., Cote, Gregory A., Forsmark, Christopher E., Gardner, Timothy B., Gelrud, Andres, Guda, Nalini M., Lewis, Michele D., Machicado, Jorge D., Muniraj, Thiruvengadam, Sandhu, Bimaljit S., Sherman, Stuart, Singh, Vikesh K., Slivka, Adam, Tang, Gong, Whitcomb, David C., Wilcox, C. Mel, Yadav, Dhiraj   +23 more
core   +2 more sources

SCPMan: Shape Context and Prior Constrained Multi-scale Attention Network for Pancreatic Segmentation [PDF]

arXiv, 2023
Due to the poor prognosis of Pancreatic cancer, accurate early detection and segmentation are critical for improving treatment outcomes. However, pancreatic segmentation is challenged by blurred boundaries, high shape variability, and class imbalance.
arxiv  

Experimental Acute Pancreatitis Models: History, Current Status, and Role in Translational Research

Frontiers in Physiology, 2020
Acute pancreatitis is a potentially severe inflammatory disease that may be associated with a substantial morbidity and mortality. Currently there is no specific treatment for the disease, which indicates an ongoing demand for research into its ...
Xinmin Yang, Linbo Yao, Xianghui Fu, Rajarshi Mukherjee, Qing Xia, Monika A. Jakubowska, Pawel E. Ferdek, Wei Huang   +7 more
doaj   +1 more source

Infected Necrosis in Severe Pancreatitis - Combined Nonsurgical Multi-Drainage with Directed Transabdominal High-Volume Lavage in Critically Ill Patients [PDF]

, 2009
Background: Infection of pancreatic necrosis is a life-threatening complication during the course of acute pancreatitis. In critically ill patients, surgical or extended endoscopic interventions are associated with high morbidity and mortality. Minimally
A. Meining, A. Umgelter, Baron, Beger, Bradley, Bradley, Branum, C. Prinz, Connor, Connor, Dellinger, Fernandez-del Castillo, Hartwig, Isenmann, J. Gaa, L. Ludwig, M. Bajbouj, McKay, Nathens, Nordback, R.M. Schmid, Sand, Sarr, Seewald, Seifert, Seifert, Tsiotos, Tzovaras, V. Becker, W. Huber, Werner, Whitcomb   +31 more
core   +1 more source

Evaluation of Canine Pancreas-Specific Lipase Activity, Lipase Activity, and Trypsin-Like Immunoreactivity in an Experimental Model of Acute Kidney Injury in Dogs. [PDF]

, 2015
BackgroundDiagnosis of pancreatitis in dogs is complicated by extrapancreatic disorders that can alter the results of laboratory tests. Extrapancreatic disorders can also affect the diagnosis of exocrine pancreatic insufficiency (EPI).
Cowgill, LD, Hulsebosch, SE, Kass, PH, Marks, SL, Palm, CA, Segev, G   +5 more
core   +1 more source

Meta-information-aware Dual-path Transformer for Differential Diagnosis of Multi-type Pancreatic Lesions in Multi-phase CT [PDF]

arXiv, 2023
Pancreatic cancer is one of the leading causes of cancer-related death. Accurate detection, segmentation, and differential diagnosis of the full taxonomy of pancreatic lesions, i.e., normal, seven major types of lesions, and other lesions, is critical to aid the clinical decision-making of patient management and treatment. However, existing works focus
arxiv  

Molecular mechanisms of pain in acute pancreatitis: recent basic research advances and therapeutic implications

Frontiers in Molecular Neuroscience, 2023
Although severe abdominal pain is the main symptom of acute pancreatitis, its mechanisms are poorly understood. An emerging body of literature evidence indicates that neurogenic inflammation might play a major role in modulating the perception of pain ...
Yongzi Wu, Chenxia Han, Rong Luo, Wenhao Cai, Qing Xia, Ruotian Jiang, Pawel E. Ferdek, Tingting Liu, Wei Huang, Wei Huang, Wei Huang   +10 more
doaj   +1 more source

Quantitative analysis of collagen remodeling in pancreatic lesions using computationally translated collagen images derived from brightfield microscopy images [PDF]

arXiv, 2023
The changes in stromal collagen play a crucial role during the pathogenesis and progression of pancreatic intraepithelial neoplasm (PanIN) to pancreatic ductal adenocarcinoma (PDAC) while misdiagnosis of PanIN is common because of the resemblance to chronic pancreatitis (CP) in its symptoms and subsequent evaluations similarities.
arxiv