Results 71 to 80 of about 472,362 (405)

Yinchenhao Decoction Protects Against Acute Liver Injury in Mice With Biliary Acute Pancreatitis by Regulating the Gut Microflora–Bile Acids–Liver Axis

Gastroenterology Research and Practice
Conclusions: These findings imply a potential link between gut microbiota dysbiosis and intrahepatic cholestasis in BAP-ALI mice and suggest that YCHD treatment may confer protection against BAP-ALI via the gut microflora–bile acids–liver axis.
Xianlin Zhao, Xiajia Wu, Qian Hu, Jiaqi Yao, Yue Yang, Meihua Wan, Wenfu Tang   +6 more
doaj   +1 more source

Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine

Frontiers in Physiology, 2019
Pancreatic acinar cells require high rates of amino acid uptake for digestive enzyme synthesis, but excessive concentrations can trigger acute pancreatitis (AP) by mechanisms that are not well understood.
Xiaoying Zhang, Xiaoying Zhang, Tao Jin, Tao Jin, Na Shi, Linbo Yao, Xinmin Yang, Chenxia Han, Li Wen, Dan Du, Peter Szatmary, Rajarshi Mukherjee, Tingting Liu, Qing Xia, David N. Criddle, Wei Huang, Michael Chvanov, Robert Sutton   +17 more
doaj   +1 more source

Hemoconcentration is associated with early faster fluid rate and increased risk of persistent organ failure in acute pancreatitis patients

JGH Open, 2020
Background Controversies existed surrounding the use of hematocrit to guide early fluid therapy in acute pancreatitis (AP). The association between hematocrit, early fluid therapy, and clinical outcomes in ward AP patients needs to be investigated ...
Tao Jin, Lan Li, Lihui Deng, Si Wen, Ruwen Zhang, Na Shi, Ping Zhu, Lan Lan, Ziqi Lin, Kun Jiang, Jia Guo, Tingting Liu, Anthony Philips, Xiaonan Yang, Vikesh K Singh, Robert Sutton, John A Windsor, Wei Huang, Qing Xia   +18 more
doaj   +1 more source

Unclassified autoimmune pancreatitis mimicking pancreatic cancer [PDF]

, 2019
A 24-year-old black male presented with a 1-week obstructive jaundice and intermittent abdominal pain, with no significant weight loss and an unsuspicious abdominal exam.
Alves, A, Marinho, R, Nunes, V, Pignatelli, N   +3 more
core   +1 more source

The global, regional, and national burden of pancreatitis in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

BMC Medicine, 2020
Background Pancreatitis is a critical public health problem, and the burden of pancreatitis is increasing. We report the rates and trends of the prevalence, incidence, and years lived with disability (YLDs) for pancreatitis at the global, regional, and ...
Guoqing Ouyang, Guangdong Pan, Qiang Liu, Yongrong Wu, Zhen Liu, Wuchang Lu, Shuai Li, Z. Zhou, Y. Wen   +8 more
semanticscholar   +1 more source

Pancreatic Cancer in Chronic Pancreatitis [PDF]

Indian Journal of Surgical Oncology, 2015
Data exists to indicate a definite association between chronic pancreatitis and pancreatic cancer. The strength of this association varies between various causes of pancreatitis, with hereditary and tropical pancreatitis more likely to result in malignancy. Pathogenesis may involve genetic factors, diabetes, smoking and alcohol consumption.
Puneet, Dhar, S, Kalghatgi, Vivek, Saraf
openaire   +2 more sources

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

An epidemiological study of diabetes mellitus in dogs attending first opinion practice in the UK [PDF]

, 2014
This study aimed to estimate the prevalence of canine diabetes mellitus (DM) in primary-care clinics in England, to identify risk factors associated with DM and to describe the survival of affected dogs.
Brodbelt, D C, Church, D B, Mattin, M J, McGreevy, P D, O'Neill, D G, Sydney, Thomson, P C   +6 more
core   +2 more sources

Acute Pancreatitis: A Multifaceted Set of Organelle and Cellular Interactions.

Gastroenterology, 2019
Acute pancreatitis is an inflammatory disorder of the exocrine pancreas associated with tissue injury and necrosis. The disease can be mild, involving only the pancreas, and resolve spontaneously within days or severe, with systemic inflammatory response
Aida Habtezion, A. Gukovskaya, S. Pandol
semanticscholar   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source