Results 81 to 90 of about 472,362 (405)

Role of Seipin in Human Diseases and Experimental Animal Models

Biomolecules, 2022
Seipin, a protein encoded by the Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2) gene, is famous for its key role in the biogenesis of lipid droplets and type 2 congenital generalised lipodystrophy (CGL2). BSCL2 gene mutations result in genetic
Yuying Li, Xinmin Yang, Linrui Peng, Qing Xia, Yuwei Zhang, Wei Huang, Tingting Liu, Da Jia   +7 more
doaj   +1 more source

Intra-abdominal hypertension and abdominal compartment syndrome in pancreatitis, paediatrics, and trauma [PDF]

, 2015
Intra-abdominal hypertension (IAH) is an important contributor to early organ dysfunction in trauma and sepsis. However, relatively little is known about the impact of intra-abdominal pressure (IAP) in general internal medicine, pregnant patients, and ...
De Keulenaer, Bart L, De laet, Inneke, De Waele, Jan, Ejike, Janeth C, Ivatury, Rao, Kimball, Edward, Kirkpatrick, Andrew W, Leppäniemi, Ari, Malbrain, Manu LNG, Roberts, Derek J   +9 more
core   +1 more source

Western-type diet influences mortality from necrotising pancreatitis and demonstrates a central role for butyrate

Gut, 2020
Objective The gut microbiota are the main source of infections in necrotising pancreatitis. We investigated the effect of disruption of the intestinal microbiota by a Western-type diet on mortality and bacterial dissemination in necrotising pancreatitis ...
F. F. van den Berg, D. van Dalen, S. Hyoju, H. V. van Santvoort, M. Besselink, W. Wiersinga, O. Zaborina, M. Boermeester, J. Alverdy   +8 more
semanticscholar   +1 more source

Poria cocos as a Functional Food for Diabetes and Diabetes‐Related Foot Ulcers

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Poria cocos is known as an edible mushroom for food and medicine. Poria cocos and its terpenes and terpenoids serve as novel remedies to treat diabetes and its ulcers. Its mode of actions includes reduction of insulin resistance, starch digestion and inflammation as well as promotion of blood vessel formation. ABSTRACT Poria cocos is a medicinal fungus
Yi‐San Lee, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +3 more
wiley   +1 more source

High ANO1 expression is a prognostic factor and correlated with an immunosuppressive tumor microenvironment in pancreatic cancer

Frontiers in Immunology
BackgroundAminooctylamine (ANO1) plays an oncogenic role in various cancers. However. its role in pancreatic cancer (PC) has rarely been studied. This study investigated the prognostic value of ANO1 and its correlation with the tumor microenvironment ...
Guangnian Zhang, Zhihui Shu, Jun Yu, Jianshui Li, Pengsheng Yi, Bin Wu, Dawei Deng, Shu Yan, Yong Li, Dongmei Ren, Yifu Hou, Yifu Hou, Chuan Lan   +12 more
doaj   +1 more source

Drug induced pancreatitis: A systematic review of case reports to determine potential drug associations

PLoS ONE, 2020
Objective A current assessment of case reports of possible drug-induced pancreatitis is needed. We systematically reviewed the case report literature to identify drugs with potential associations with acute pancreatitis and the burden of evidence ...
D. Wolfe, S. Kanji, F. Yazdi, P. Barbeau, D. Rice, Andrew Beck, C. Butler, Leila Esmaeilisaraji, B. Skidmore, D. Moher, B. Hutton   +10 more
semanticscholar   +1 more source

Autoimmune pancreatitis mimicking pancreatic tumor [PDF]

Journal of Surgical Case Reports, 2012
Autoimmune pancreatitis (AIP) is a rare disease of unknown pathomechanism. It belongs to the IgG4-related disease family and responds well to steroids, although the relapse rate can reach up to 20-30%. Differentiating AIP from the more common pancreatic cancer can be very challenging.
Dede, Kristóf, Salamon, Ferenc, Taller, András, Teknős, Dániel, Bursics, Attila   +4 more
openaire   +2 more sources

Validation of the Safe Application of Tokyo Guideline 2018 (TG18) Severity Grading and Treatment Algorithm in Super‐Elderly Patients Aged 85 and Over With Acute Cholecystitis: A Study in the Japanese Tertiary Care Hospital

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background With population aging and extended healthy life expectancy, the management of acute cholecystitis (AC) in patients aged ≥ 85 years has evolved. However, the Tokyo Guidelines 2018 (TG18) for AC provide no specific risk assessment criteria for this population.
Yuta Kobayashi, Ryo Oikawa, Yumi Shibuya, Masakazu Tatsuno, Atsuya Kamiyama, Tsuyoshi Ozawa, Keiichiro Hara, Shinogu Hatano, Shojiro Hata, Hirokazu Yamaguchi   +9 more
wiley   +1 more source

Targeting Macrophage Migration Inhibitory Factor in Acute Pancreatitis and Pancreatic Cancer

Frontiers in Pharmacology, 2021
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine implicated in the pathogenesis of inflammation and cancer. It is produced by various cells and circulating MIF has been identified as a biomarker for a range of diseases ...
Yongjian Wen, Yongjian Wen, Yongjian Wen, Wenhao Cai, Wenhao Cai, Jingyu Yang, Xianghui Fu, Lohitha Putha, Qing Xia, John A. Windsor, Anthony R. Phillips, Anthony R. Phillips, Joel D. A. Tyndall, Dan Du, Tingting Liu, Wei Huang, Wei Huang   +16 more
doaj   +1 more source

Pancreatic diseases [PDF]

Wiener Medizinische Wochenschrift, 2014
The author presents his personal choice of practical relevant papers of pancreatic diseases from 2014 to 2015. Nutritional factors and hypertriglycidemia are discussed as causes of acute pancreatitis. Tools to avoid post-ERCP(endoscopic retrograde cholangiopancreatography) pancreatitis are described and the natural course of fluid collections and ...
openaire   +3 more sources