Results 31 to 40 of about 21,252 (207)
Stereoselective pharmacokinetics of stable isotope (+/-)-[13C]-pantoprazole: Implications for a rapid screening phenotype test of CYP2C19 activity [PDF]
AIMS: We have previously shown that the (±)-[(13) C]-pantoprazole breath test is a promising noninvasive probe of CYP2C19 activity. As part of that trial, plasma, breath test indices and CYP2C19 (*2, *3, and *17) genotype were collected.
Desta, Zeruesenay +4 more
core +1 more source
Head-to-head comparison of H2-receptor antagonists and proton pump inhibitors in the treatment of erosive esophagitis: A meta-analysis [PDF]
Aim: To systematically evaluate the efficacy of H2-receptor antagonists (H2RAs) and proton pump inhibitors in healing erosive esophagitis (EE). Methods: A meta-analysis was performed.
Huang, JQ +6 more
core +1 more source
Antimicrobial Activity, Acute Toxicity and Cytoprotective Effect of Crassocephalum Vitellinum (Benth.) S. Moore Extract in a Rat Ethanol-HCl Gastric Ulcer Model. [PDF]
A decoction of Crassocephallum vitellinum (Benth.) S. Moore (Asteraceae) is used in Kagera Region to treat peptic ulcers. This study seeks to evaluate an aqueous ethanol extract of aerial parts of the plant for safety and efficacy.
A Ramesh +27 more
core +1 more source
The aim of this study was to investigate the effect of preemptive pantoprazole infusion on early endoscopic findings in patients with acute ulcer bleeding. Records of 333 patients admitted with acute ulcer bleeding were analyzed.
Istvan Rácz +6 more
doaj +1 more source
A Statistical Model for Stroke Outcome Prediction and Treatment Planning
Stroke is a major cause of mortality and long--term disability in the world. Predictive outcome models in stroke are valuable for personalized treatment, rehabilitation planning and in controlled clinical trials.
Bhattacharya, Sakyajit +3 more
core +1 more source
Repositioning proton pump inhibitors as anticancer drugs by targeting the thioesterase domain of human fatty acid synthase [PDF]
Fatty acid synthase (FASN), the enzyme responsible for de novo synthesis of free fatty acids, is up-regulated in many cancers. FASN is essential for cancer cell survival and contributes to drug resistance and poor prognosis.
Fako, Valerie E. +4 more
core +5 more sources
Background: Liver transplant recipients are frequently treated with proton pump inhibitors. Drug interactions have been described especially with respect to omeprazole.
Sebastian C. B. Bremer +12 more
doaj +1 more source
Background: Proton pump inhibitors (PPIs) are the most effective medications in acid-related disorders. Inappropriate use of Intravenous (IV) pantoprazole can cause unwanted consequences like hypersensitivity reactions, prolonged duration of treatment ...
Majid Iranshahi +5 more
doaj
The corrosion behavior of pipeline steel grade API 5L X52 immersed in a 1M HCl aqueous solution in the presence and absence of Pantoprazole, was evaluated using EIS.
A. Espinoza-Vázquez +5 more
doaj +1 more source
Objective: To evaluate the rational use of Pantoprazole by analyzing the appropriateness of prescription. Methodology: This cross-sectional study was performed within four months in 150 patients hospitalized in Kempegowda Institute of Medical Sciences ...
Shamimeh Fallah Ghorbani, Kiran Nagaraju
doaj +1 more source

