Results 51 to 60 of about 13,127 (165)

Calvarial Metastasis of Breast Carcinoma Manifesting as a New Daily Persistent Headache: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT New‐onset daily persistent headache (NDPH) is a primary headache syndrome characterized by a sudden onset of daily headaches persisting for more than three months in patients with no prior headache history. We report the case of a 49‐year‐old Indian lady who presented to the neurology outpatient clinic with new daily persistent headache.
Neha Lall   +3 more
wiley   +1 more source

Tacrolimus‐Associated Calcium Pyrophosphate Crystal Arthritis in a Kidney Transplant Recipient: An Underrecognized Condition

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Providers who care for renal transplant recipients should be aware of the possibility of tacrolimus‐associated CPPD in patients who present with arthritis. In the case presented, a delayed diagnosis led to the progression of symptoms and avoidable disability, underscoring the need for greater clinical awareness of this condition within the ...
Matthew Wyke   +5 more
wiley   +1 more source

Effect of pantoprazole and Helicobacter pylori therapy on uninvestigated dyspeptic patients

open access: yesThe Turkish Journal of Gastroenterology, 2015
Background/Aims: This study aimed to test the efficacy of empirical proton pump inhibitor use and Helicobacter pylori therapy for uninvestigated dyspepsia in a population with a high prevalence of H. pylori.
Birol Baysal   +8 more
doaj   +1 more source

A Rare Constellation of Peripartum Cardiomyopathy Manifesting With Multiple Thromboembolic Phenomena in a 15‐Year‐Old

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 15‐year‐old postpartum primipara presented at 19 days with aphasia, right hemiparesis, chest pain, and dyspnea. Diagnostics confirmed concurrent cardioembolic stroke and pulmonary embolism secondary to peripartum cardiomyopathy (ejection fraction 29%).
Reuben E. Mkama   +39 more
wiley   +1 more source

A possible involvement of Nrf2-mediated heme oxygenase-1 up-regulation in protective effect of the proton pump inhibitor pantoprazole against indomethacin-induced gastric damage in rats

open access: yesBMC Gastroenterology, 2012
Background Proton pump is an integral membrane protein that is ubiquitous ATP binding cassette (ABC) involved in many transport processes in all living organisms, among which a specialized form of pump, so called p-type proton pump, exists in the ...
Lee Ho-Jae   +4 more
doaj   +1 more source

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 412-419, August 2026.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park   +2 more
wiley   +1 more source

Impact of CYP2C19 and CYP3A4 Inhibitor Use on Clopidogrel Clinical Effectiveness in CYP2C19 Genotyped Patients Undergoing Percutaneous Coronary Intervention

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 531-541, August 2026.
CYP2C19 and CYP3A4 contribute to clopidogrel bioactivation. CYP2C19 no‐function alleles diminish clopidogrel's antiplatelet effects and clinical effectiveness. Coadministration of either a CYP2C19 or a CYP3A4 inhibitor may also reduce clopidogrel's antiplatelet effects and lead to phenoconversion in patients without a CYP2C19 no‐function allele (normal/
Danwei Shao   +8 more
wiley   +1 more source

Effect of bundle care strategy on rebleeding rate and prognosis of patients with upper gastrointestinal bleeding in emergency observation area

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 4, August 2026.
Abstract Background Upper gastrointestinal bleeding (UGIB) is a life‐threatening emergency. This study evaluated the effects of a bundle care strategy on rebleeding and prognosis in patients with UGIB in the emergency observation area. Methods A retrospective cohort study was conducted among 206 patients with UGIB admitted to the emergency observation ...
Lianmei Guo, Jing Wang, Qiuxiang Hu
wiley   +1 more source

Efficacy Comparison of Divided and Infusion Intravenous Pantoprazole Methods after Endoscopic Therapy in Patients with Acute Gastrointestinal Bleeding

open access: yesAdvanced Biomedical Research, 2017
Background: Intravenous pantoprazole administration in patients with severe bleeding under urgent endoscopic therapy is effective. Furthermore, its infusion dose is useful to control bleeding; however, it is not economical.
Amin Motiei, Vahid Sebghatolahi
doaj   +1 more source

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