Results 71 to 80 of about 13,127 (165)

CYP2C19 c.681G>A Is not in Complete Linkage Disequilibrium With c.332‐23A>G: Implications for Pharmacogenetic Testing

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT CYP2C19 plays an important role in the metabolism of many medications, including the antiplatelet agent clopidogrel, the antifungal agent voriconazole, selective serotonin reuptake inhibitors, select tricyclic antidepressants, and proton pump inhibitors.
Amy J. Turner, Erin C. Boone, Cyrine E. Haidar, Wenjian Yang, Ashley D. Derezinski, Andrew Haddad, Philip E. Empey, Ulrich Broeckel, Andrea Gaedigk   +8 more
wiley   +1 more source

Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae

Frontiers in Pharmacology
The development of resistance to carbapenems in Klebsiella pneumoniae due to the production of metallo-β-lactamases (MBLs) is a critical public health problem because carbapenems are the last-resort drugs used for treating severe infections of extended ...
Wesam H. Abdulaal, Nabil A. Alhakamy, Nabil A. Alhakamy, Nabil A. Alhakamy, Amer H. Asseri, Amer H. Asseri, Mohamed F. Radwan, Tarek S. Ibrahim, Solomon Z. Okbazghi, Hisham A. Abbas, Basem Mansour, Aly A. Shoun, Wael A. H. Hegazy, Wael A. H. Hegazy, Mahmoud Saad Abdel-Halim   +14 more
doaj   +1 more source

ИСПОЛЬЗОВАНИЕ ИНГИБИТОРОВ ПРОТОННОЙ ПОМПЫ ДЛЯ ЛЕЧЕНИЯ КИСЛОТОЗАВИСИМЫХ ЗАБОЛЕВАНИЙ

Архивъ внутренней медицины, 2013
Proton pump inhibitors take the leading place in treatment of acid-related diseases of the digestive system. Compared to other proton pump inhibitors pantoprazole (Controloc) has higher chemical stability and less potential for interaction with hepatic ...
Л. Б. Лазебник, Е. Д. Ли, О. М. Михеева   +2 more
doaj   +1 more source

Bridging the Pregnancy Knowledge Gap: A Real‐World Analysis of Medication Use and Drug–Drug Interaction Risk in Crohn's Disease and Multiple Sclerosis

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT The exclusion of pregnant individuals from clinical trials has resulted in a significant medical knowledge gap for this population. Leveraging real‐world data (RWD) provides a critical window into the prevalence and use of medications during pregnancy.
Jacqueline Williams, Rucha Sane, Amita Joshi, Kit Wun Kathy Cheung, Bianca Vora   +4 more
wiley   +1 more source

Pantoprazole – safety in drug-drug interaction

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
The aim of review. To carry out comparative analysis of metabolic pathways of proton pump inhibitors (PPI), to determine the agent with lowest effect on activity of cytochrome CYP2C19 isoenzyme for improvement of safety of combined treatment by ...
E. V. Shikh, D. A. Sychev
doaj  

Pantoprazole-related Symptomatic Hyponatremia

European Journal of Case Reports in Internal Medicine, 2016
Hyponatremia is the most common electrolyte balance disorder, especially in the elderly and polymedicated population. The authors report the case of an 83-year-old man with symptomatic severe hyponatremia due to Syndrome of Inappropriate Antidiuretic ...
Filipa Ferreira, Sofia Mateus, Ana Rita Santos, Hugo Moreira, Nuno Ribeiro Ferreira   +4 more
doaj   +1 more source

Skin Acceptability of a Topical Cream Containing Zinc Oxide, Zinc Gluconate, Taurine and Panthenol in Females With Urinary Incontinence

Journal of Cosmetic Dermatology, Volume 25, Issue 8, August 2026.
ABSTRACT Background Incontinence‐associated dermatitis (IAD) can be exacerbated by friction and occlusion from a diaper/incontinence pad. Skin barrier function in IAD can be preserved through humectant and emollient‐containing protective agents. Aims To investigate the efficacy, skin acceptability, and cosmetic qualities of a cream containing zinc ...
Leonardo Celleno, Linda Landini, Dalia Mostafa Kamal, Fabrizio Mazzicone   +3 more
wiley   +1 more source

Profuse nocturnal eyelid haemorrhage from a spider angioma

Acta Ophthalmologica, Volume 104, Issue 5, Page 586-587, August 2026.
Ype P. de Jong, Paulus T. V. M. de Jong
wiley   +1 more source

Assessment of Burden of Partial Response to Standard Doses of Proton Pump Inhibitors in Patients with Clinically Diagnosed Gastroesophageal Reflux Disease: A Real-World Evidence Study in India

Drugs - Real World Outcomes
Background Partial response to standard-dose proton pump inhibitors (PPIs) in gastroesophageal reflux disease (GERD) is common, yet real-world data on its burden and management in Indian settings remain limited.
Yogesh Garje, Rajiv Saikia, Sunil Gupta, Soujanya Peri, Praveen Sharma, Shruti Dharmadhikari, Ashwini Satpathy, Chintan Khandhedia, Neeraj Markandeywar, Amey Mane, Suyog Mehta, Sadhna Joglekar   +11 more
doaj   +1 more source

Intravenous pantoprazole versus famotidine for epigastric pain in the emergency department: A triple-blind randomized clinical trial

Journal of Acute Disease
Objective: To compare the therapeutic efficacy of intravenous pantoprazole and famotidine for the treatment of epigastric pain in patients presenting to the emergency department.
Mahjoubeh Keykha, Sahar Yousefi, Alireza Bahmani   +2 more
doaj   +1 more source