Results 101 to 110 of about 63,884 (240)
Papain Injection Creates a Nucleotomy-like Cavity for Testing Gels in Intervertebral Discs
GelsBiomaterials, such as hydrogels, have an increasingly important role in the development of regenerative approaches for the intervertebral disc. Since animal models usually resist biomaterial injection due to high intradiscal pressure, preclinical testing
Jan Ulrich Jansen +5 more
doaj +1 more source
, 2023 51 p.This study focused on formulating and characterizing hydrogel films containing papain, an enzyme extracted and purified from ripe papaya latex. Papain demonstrated enzymatic activity (0.0749 U/mg) and was incorporated into HPMC-based hydrogels using
Chau, Thi Thu Suong
core
Brain Pathology, EarlyView.How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova +11 more
wiley +1 more source
Influence of high pressure and papain treatment on some aspects of beef meat quality
Czech Journal of Food Sciences, 2004 Influence of post-rigor injection of papain solution and/or high pressure treatment (100, 200, 300 MPa for 10 min) on the quality of beef meat (musculus longissimus lumborum et thoracis) was studied in terms of texture, microbial quality and some physico-
N. Schenková +5 more
doaj +1 more source
Redox and catalytic properties of modified papain [PDF]
, 2010 Redox and Catalytic Properties of Modified Papain Endopeptidase papain could be modified by the organometallic complex [(η6 -C6H5(CH2)2NHCO(CH2)Cl)Ru(N^N)Cl]Cl, (N^N) = 1,10-phenanthroline (TB11), which binds to the free sulfhydryl group of cysteine in ...
Lachmanová, Štěpánka
core
Substrate specificity pockets of MOA and papain.
, 2016 The left and center panels show the solvent-exposed surface at the specificity-determining S2 subsite of papain (A) or MOA (B). A structural alignment of the two proteins (panel C) shows a more shallow S2 binding pocket in MOA compared to papain ...
Ute Krengel (2267728) +5 more
core +1 more source
Brain Pathology, EarlyView.Brain metastasis‐associated fibroblasts are active stromal components of the metastatic niche characterised by extracellular matrix remodelling and production of pro‐migratory mediators. They promote monocyte and cancer cell migration and enhance cancer cell invasion while having no growth‐promoting effect on cancer cells.
Barbora Výmolová +19 more
wiley +1 more source
Bulletin of the National Research CentreBackground Diabetic kidney injury is associated with renal bioenergetic disturbance, redox imbalance and impaired mitochondrial biogenesis signalling.
Oluwagbenga Mayowa Adu +2 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Cerebral ischaemia is a leading cause of death in older adults and imposes a substantial global economic burden. Recent studies indicate that inhibiting the Gαs‐coupled EP2 receptor reduces ischaemic brain injury by modulating neuroinflammation.
Zhen Jin +7 more
wiley +1 more source
Cancer Science, EarlyView.This study demonstrates the selective depletion of tumor‐associated macrophages (TAMs) by targeting CSF1R through near‐infrared photoimmunotherapy (NIR‐PIT). Using a combination of anti‐CSF1R Fab‐IR700 conjugates and localized light irradiation, we achieved tumor suppression and durable antitumor immunity without systemic toxicity.
Kohei Nakajima +6 more
wiley +1 more source