Results 101 to 110 of about 51,553 (242)

Therapeutic Potential of Carica papaya (L.) Extract on NRF2/KEAP1 and Apoptotic Pathways in Asbestos‐Induced Lung Toxicity

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Asbestos exposure induced oxidative stress, apoptosis, and lung tissue damage in animal models. Treatment with Carica papaya (500 mg/kg) extract improved antioxidant status, reduced oxidative stress biomarkers, and restored lung architecture. Gene expression analysis showed modulation of NRF2/KEAP1 and apoptotic pathways.
Usman Haider, Muhammad Ahmad, Wania Nasir, Najeeb Ullah Khan, Muhammad Saad Tariq, Bilal Aslam, Saif Ur Rehman, Junming Sun   +7 more
wiley   +1 more source

Discovery and Structural Characterization of a Highly Protective Neutralizing Antibody Targeting the Mpox Virus A35R Protein

MedComm, Volume 7, Issue 7, July 2026.
High‐affinity monoclonal antibodies (mAbs) targeting the MPXV EEV protein A35R were rapidly isolated using mRNA‐LNP vaccination and the Beacon single‐cell sorting Optofluidic platform, followed by functional profiling. One mAb, 17H1, potently neutralized authentic MPXV and conferred complete protection in vivo.
Shimeng Bai, Shuo Song, Xin Wang, Yuxin Xiao, Yun Long, Fenfang Wu, Fuxiang Wang, Zhongyi Fan, Jianqing Xu, Maozhou He, Hongzhou Lu   +10 more
wiley   +1 more source

Coronavirus M Protein Hijacks Toll‐Interacting Protein (TOLLIP) to Suppress NF‐κB Signaling and Promote Immune Evasion

MedComm, Volume 7, Issue 7, July 2026.
Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang, Lu Kang, Yu Zhong, Songjun Shao, Senren Xue, Changliang Liu, Xiaoqi Zheng, Jing‐Wen Lin, Yu Chen, Fengming Luo, Huajing Wan   +10 more
wiley   +1 more source

Occupational Contact Urticaria, Protein Contact Dermatitis and Concomitant Airway Diseases in the Finnish Register of Occupational Diseases in 2005–2020: Main Causes and Occupations at Risk

Contact Dermatitis, Volume 95, Issue 1, Page 74-85, July 2026.
This Finnish registry study shows that concomitant occupational asthma and rhinitis are common in patients with occupational contact urticaria or protein contact dermatitis, often sharing the same exposure. When evaluating occupational immediate allergy, both skin and airway symptoms should be considered.
Ville Ojanen, Liisa Airaksinen, Hille Suojalehto, Kirsi Koskela, Maria Pesonen   +4 more
wiley   +1 more source

Selective Autophagy Receptor CsNBR1 Confers Citrus Huanglongbing Resistance by Degrading ‘Candidatus Liberibacter Asiaticus’ Virulence Effectors

Molecular Plant Pathology, Volume 27, Issue 7, July 2026.
Overexpression of CsNBR1 confers HLB resistance in citrus by degrading CLas effector proteins, including SDE5115, SDE1, SDE19 and SDE5, via the autophagy pathway. ABSTRACT The selective autophagy receptor NEIGHBOUR OF BRCA1 (NBR1) is a key regulator of plant immunity, but its role against bacterial pathogens remains poorly understood.
Yaqian Shi, Xuejin Cui, Fang Fang, Zaiyu Yang, Yalin Mei, Shimian Ma, Changyong Zhou, Xuefeng Wang   +7 more
wiley   +1 more source

CitPH4 Confers Resistance to Citrus Canker by Activating Papain‐Like Cysteine Protease

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4561-4576, July 2026.
ABSTRACT Citrus canker, a devastating disease caused by Xanthomonas citri subsp. citri (Xcc), poses a significant threat to global citrus production due to the high susceptibility of nearly all commercial citrus cultivars to it. Although transcription factor Citrus PH4 (CitPH4) is well known for regulating fruit acidity, its potential role in plant ...
Tao Yuan, Rongyan Huang, Zhihao Lu, Yujun Zhao, Jingchao Lv, Jiaxian He, Shengjie Lin, Chunyang He, Xukai Liu, Kun Yang, Jialing Fu, Juan Sun, Li Liao, Weikang Zheng, Wang Zhang, Huihui Jia, Yuantao Xu, Xia Wang, Qiang Xu, Fang Ding, Bin Hu   +20 more
wiley   +1 more source

PolyGraph – Flexible, Biocompatible & Electrically Optimized Graphene‐Polymer Composites for Next‐Generation Neural Interfaces

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
PolyGraph, a flexible graphene‐polycaprolactone nanocomposite, unites conductivity, biocompatibility, and processability for next‐generation neural interfaces. Fabricated into microneedle arrays with ultra‐flexible backings, PolyGraph enables bidirectional neuronal recording and stimulation in brain tissue, advancing brain‐computer interface (BCI) and ...
Jack Maughan, Ian Woods, Cian O'Connor, Pablo Quintana‐Sarti, Eoin Caffrey, Jose M. Munuera, Tian Carey, Adrian Dervan, Alejandro López Valdés, Omar Mamad, Maeve A. Caldwell, Fergal J. O'Brien, Jonathan N. Coleman   +12 more
wiley   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, Volume 38, Issue 34, 17 June 2026.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

Safety evaluation of the food enzyme papain, a cysteine endopeptidase complex from the latex of <i>Carica papaya</i> L. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, de Marzo Solano M, Van Loveren H, Vernis L, Fraguas CF, Cavanna D, Liu Y.   +15 more
europepmc   +3 more sources

Thiolated Polymers in 3D Bioprinting: Control of Gelation

Advanced Materials, Volume 38, Issue 35, 23 June 2026.
Thiolated polymers are established as programmable bioinks for 3D bioprinting, integrating versatile crosslinking chemistries with redox‐responsive control. This work demonstrates how molecular design and external triggers define gelation kinetics, printability windows, and structural fidelity, enabling stable, high‐resolution constructs and advancing ...
Soheil Haddadzadegan, Flavia Laffleur, Andreas Bernkop‐Schnürch   +2 more
wiley   +1 more source