Results 111 to 120 of about 63,884 (240)

Stabilization of papain by modification with chitosan

open access: yes, 2002
Papain (EC 3.4.22.2) was immobilized on chitosan by adsorption and subsequent cross-linking with glutaraldehyde. The immobilized papain displayed a lower specific activity than did the native enzyme.
Ali Kılınç   +5 more
core  

PEG400 regulates Falcipain 2 activity through an allosteric mechanism

open access: yesThe FEBS Journal, EarlyView.
Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath   +2 more
wiley   +1 more source

Proteolytic Activity of Zingiber officinale Extract: Interaction With Myofibrillar Proteins of Different Origins and Functional Effects in Meat Systems [PDF]

open access: yesFood Sci Nutr
Ginger‐derived proteases were evaluated for their proteolytic activity toward isolated chicken and pork myofibrils and their effects during meat marination. The ginger extract showed a selective and moderate proteolytic activity, resulting in controlled protein degradation and improved meat quality, including tenderness, juiciness, flavor, and overall ...
Crinò A, Fabrizi C, Menci A, Liburdi K.
europepmc   +2 more sources

Characterization of dermatan sulfate and chondroitin sulfate profiles during brain regeneration in Styela plicata

open access: yesThe FEBS Journal, EarlyView.
Adult ascidians are capable of regenerating their entire brains following injury, and glycosaminoglycans have been shown to either promote or inhibit neuritogenesis. In this study, dermatan 2,6‐disulfate (D2,6S) was identified as the predominant complex carbohydrate in the ascidian brain.
Taynan Motta Portal   +5 more
wiley   +1 more source

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

open access: yesThe FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas   +4 more
wiley   +1 more source

Effects of Low Temperature–Ultrasound–Papain (LTUP) Combined Treatments on Purine Removal from Pork Loin and Its Influence on Meat Quality and Nutritional Value

open access: yesFoods
A combined pretreatment method of “low temperature-ultrasound-papain” (LTUP) was proposed to remove the purine of pork loins. Compared with untreated pork loin, under optimal conditions (temperature 58 °C, ultrasound density 100 W/cm2, and papain ...
Jiaojiao Yuan   +3 more
doaj   +1 more source

Fluoride‐Free Mouthwashes Available Over‐The‐Counter in the US‐An Overview

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose Fluoride‐free mouthwashes (FFM) are commonly used by patients for a variety of cosmetic and/or therapeutic reasons. The purpose of this study was to investigate the composition and purposes of FFM available over‐the‐counter in the US.
Astrid C. Valdivia‐Tapia   +3 more
wiley   +1 more source

Soluble Papain to Digest Monoclonal Antibodies; Time and Cost-Effective Method to Obtain Fab Fragment [PDF]

open access: yes
Antigen binding fragments (Fabs) used in research (e.g., antibody mimetics, antibody-drug conjugate, bispecific antibodies) are frequently obtained by enzymatic digestion of monoclonal antibodies using immobilised papain.
Collins, Matthew, Khalili, Hanieh
core   +1 more source

Transcriptomic profiling of subpopulations of mouse embryonic subplate neurons

open access: yesJournal of Anatomy, EarlyView.
To study gene expression in subpopulations of cortical subplate neurons (Lpar1‐EGFP‐positive and D1B‐positive SpN clusters), we applied gene expression profiling, including bulk microarray analysis, single‐cell RNA sequencing (scRNA‐seq), and Visium spatial transcriptomics, and identified both overlapping and unique gene expression signatures ...
Hitomi Achiwa   +8 more
wiley   +1 more source

Chemical agents to control biofilm formation in step 1 of care—Toothpastes and mouthwashes/concepts and challenges

open access: yesPeriodontology 2000, EarlyView.
Abstract Maintaining optimal oral hygiene is important for overall oral care, ensuring the well‐being of teeth and their surrounding tissues. In addition, it promotes fresh breath and a pleasing smile. A key element of oral self‐care is the daily use of toothpaste during regular brushing.
Maud Joosstens   +2 more
wiley   +1 more source

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