Results 121 to 130 of about 51,627 (231)

Sphingosine‐1‐Phosphate Receptor 1 Regulates Competition Dependent Astrocyte Morphogenesis and Tiling in Murine Cortex

Glia, Volume 74, Issue 8, August 2026.
Neuronal contact‐induced expression of S1PR1 in astrocytes is regulated by JAK‐STAT3 signaling. Astrocytic S1PR1 modulates cortical astrocyte morphogenesis. Astrocytic S1PR1 regulates astrocyte territorial overlap/tiling in a competition dependent manner.
Jean Patrick M. Gonzales, Connor Tuck, Surya Chandra Rao Thumu, Soha Munir, Jaden Harris, Hunain (Zeik) Tariq, Paul Marcelli, Oscar Dominguez, Kaviya Suriyakumar Anbazagan, Sandeep K. Singh   +9 more
wiley   +1 more source

Up-Regulation of the TRPM8 Channel Attenuates TRPC1-Mediated Store-Operated Calcium Entry in Abdominal Aortic Aneurysm. [PDF]

Biomolecules
Wang YQ, Pan M, Lin YC, Zheng SY, Chen QY, Gui LX, Lin MJ, Lin DC.   +7 more
europepmc   +1 more source

Camouflage Protein‐Engineered Extracellular Vesicles Alleviate TMJ‐OA by Hijacking Caspase‐1 to Suppress Pyroptosis

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
ABSTRACT Temporomandibular joint osteoarthritis (TMJ‐OA) is highly prevalent with an insidious onset. Severe inflammation and significant degenerative changes are often associated with the condition, and current clinical treatments remain inadequate. In this study, we focus on pyroptosis and engineered the camouflage protein (GSDMD‐C) attached to the ...
Yufei Liu, Jie Zhou, Yukang Wang, Zhihui Hu, Guimin Yin, Mengsen Zhu, Jianke Huo, Chenyang Zhang, Yiming Wang, Shuang Fu, Jinpeng Wan, Jie Wang, Lanju Xu, Zhiling Zhang, Shufang Wang   +14 more
wiley   +1 more source

Effects of Exogenous Tannase and Papain on the Flavor Quality of Black Tea During Fermentation. [PDF]

Foods
Lei X, Li C, Wang LX, Huang SN, Jiang XF.   +4 more
europepmc   +1 more source

Reprogramming Glial Cell Metabolism via a tRNA Fragment Preserves Vision in Retinal Neurodegeneration

MedComm, Volume 7, Issue 8, August 2026.
Under oxidative and excitotoxic stress, Müller cell‐derived 5′tiRNA‐His‐GTG contributes to retinal neurodegeneration. Pathological stimuli increase ANG‐dependent production of 5′tiRNA‐His‐GTG, which suppresses LPCAT1 expression and disrupts phosphatidylcholine (PC)‐mediated glycerophospholipid metabolism.
Yuke Ji, Sha Liu, Ying Zhang, Junya Zhu, Chang Huang, Ya Zhao, Jiao Xia, Wan Mu, Jin Yao, Biao Yan   +9 more
wiley   +1 more source

Technical and biological factors driving inter-individual body burden of arsenic species in murine models of human arsenic exposure. [PDF]

Toxicol Sci
Wang L, Wang Q, Wolfe TM, Pinkham NV, Erickson R, Yoshinaga M, McDermott TR, Walk ST.   +7 more
europepmc   +1 more source

Neuroprotective Effects of RNS60 in TDP‐43 Pathology‐Associated Amyotrophic Lateral Sclerosis

Muscle &Nerve, Volume 74, Issue 2, Page 463-473, August 2026.
ABSTRACT Introduction TDP‐43 pathology is broadly observed in the cerebral cortex of patients with amyotrophic lateral sclerosis (ALS). RNS60, an experimental treatment for acute ischemic stroke and ALS, enhanced mitochondrial biogenesis and function in other preclinical models.
Danny R. Vesevick, Supurna Ghosh, Andreas Kalmes, P. Hande Ozdinler, Mukesh Gautam   +4 more
wiley   +1 more source

Chondroitinase Versus Papain Digestion Leads to Different Outcome for In Vitro Simulation of Degenerated Discs. [PDF]

JOR Spine
Jansen JU, Teixeira GQ, Salzer E, Vernengo A, Grad S, Ito K, Neidlinger-Wilke C, Wilke HJ.   +7 more
europepmc   +1 more source

Papaya‐Leaf‐Assisted Fermentation for Enhanced Extraction of Cassava Peel Starch and Its Application in Biodegradable Films

Starch - Stärke, Volume 78, Issue 8, August 2026.
Papaya‐leaf‐assisted fermentation enhanced cassava‐peel starch recovery relative to fermentation without leaves and direct grinding, while lowering nitrogenous residues. Films plasticized with glycerol and acetic acid exhibited disrupted starch hydrogen bonding, loss of A‐type crystallinity, and pronounced hydrophilicity. Soil‐burial tests showed rapid,
Onyinyechi Assumpta Ononuju, Obioma Gertrude Onukwube, Ikechukwu Chibuzo Ukaga, Chinonye Francisca Chijioke, Amarachi Udoka Nkwoada, Simeon Chukwudozie Nwanonenyi, Marta González Plaza, Nnamdi Lawrence Obasi, Cynthia Ekwy Ogukwe, Martin Onwu Chidozie Ogwuegbu   +9 more
wiley   +1 more source

Formulation of mucoadhesive dissolving film containing cinnamaldehyde and chitosan incorporating papain enzyme for inhibit oral candidiasis: in vitro study. [PDF]

Sci Rep
Akhriani AA, Mutmainnah SF, Musyrifah N, Arfansyah A, Fajriani S, Djamaluddin N, Marlina E, Ariani MD.   +7 more
europepmc   +1 more source