Results 121 to 130 of about 51,553 (242)

Chitosan/reduced graphene oxide/papain nanocomposite: a bioactive platform for skincare and biomedical applications. [PDF]

Sci Rep
Elhami N, Pazhang M.
europepmc   +1 more source

Status Epilepticus Alters the Function of Brain‐Derived Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
ABSTRACT Epilepsy is a neurological disorder characterised by recurrent spontaneous seizures. Approximately 30% of patients are unable to achieve adequate seizure control with available medications, highlighting the need to better understand disease mechanisms and develop improved treatments.
Samantha L. Reed, Yilin Wang, Yangping Li, Guoku Hu, Jingjing Yang, Bing Yao, Andrew Escayg   +6 more
wiley   +1 more source

A Multidisciplinary Analytical Strategy for the Authentication and Quality Assessment of Bromelain in Dietary Supplements. [PDF]

Int J Mol Sci
Benetti F, Petrini E, Sordi R, Gaio E, Biagi M.   +4 more
europepmc   +1 more source

HIV Tat‐Stimulated Microglial Extracellular Vesicles Are Enriched for Ferroptosis Mediators: Role of Dysregulated Autophagy

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) serve as conduits for intercellular communication, under both physiological and pathological contexts. During disease pathogenesis, microglia‐derived EVs (MEVs) play a key role in transferring pathological cargo to the recipient cells, thereby modulating their phenotype and function.
Seema Singh, Elias Horanieh, Craig L. Semerad, Palsamy Periyasamy, Susmita Sil, Shilpa Buch   +5 more
wiley   +1 more source

Up-Regulation of the TRPM8 Channel Attenuates TRPC1-Mediated Store-Operated Calcium Entry in Abdominal Aortic Aneurysm. [PDF]

Biomolecules
Wang YQ, Pan M, Lin YC, Zheng SY, Chen QY, Gui LX, Lin MJ, Lin DC.   +7 more
europepmc   +1 more source

Viscoelastic and Morphologic Changes in the Lumbar Intervertebral Discs of the 5xFAD Mouse Model of Alzheimer's Disease

JOR SPINE, Volume 9, Issue 2, June 2026.
The intervertebral discs (IVDs) from mice with amyloid pathologies are larger, flatter, and exhibit increased energy absorption, making these IVDs more susceptible to damage. This heightened vulnerability may predispose elderly individuals with AD to disc injuries, accelerating IVD degeneration and spinal pain. ABSTRACT Background Chronic low back pain,
C. E. Gonzalez, C. A. Schurman, K. A. Wilson, B. Schilling, L. M. Ellerby, S. Y. Tang   +5 more
wiley   +1 more source

Effects of Exogenous Tannase and Papain on the Flavor Quality of Black Tea During Fermentation. [PDF]

Foods
Lei X, Li C, Wang LX, Huang SN, Jiang XF.   +4 more
europepmc   +1 more source

Technical and biological factors driving inter-individual body burden of arsenic species in murine models of human arsenic exposure. [PDF]

Toxicol Sci
Wang L, Wang Q, Wolfe TM, Pinkham NV, Erickson R, Yoshinaga M, McDermott TR, Walk ST.   +7 more
europepmc   +1 more source

Comparative Analysis of Dual‐miRNA Mediated Stimulation of Nucleus Pulposus and Bone Marrow Derived Stem Cells for Intervertebral Disc Repair

JOR SPINE, Volume 9, Issue 2, June 2026.
Nucleus pulposus (NP) and bone marrow derived stem cells (BMSCs) transfected with miRNA‐149‐5p‐mimic and 221‐3p‐inhibitor were evaluated in goat monolayer, microtissue, and ex vivo organ cultures of mild degeneration. miRNA‐treated NP cells demonstrated an anti‐catabolic and pro‐discogenic response in organs, highlighting its potential as a ...
Tara Ní Néill, Niamh Wilson, Jake McDonnell, Fergal J. O'Brien, Caroline M. Curtin, James E. Dixon, Pieter A. J. Brama, Conor T. Buckley   +7 more
wiley   +1 more source

Chondroitinase Versus Papain Digestion Leads to Different Outcome for In Vitro Simulation of Degenerated Discs. [PDF]

JOR Spine
Jansen JU, Teixeira GQ, Salzer E, Vernengo A, Grad S, Ito K, Neidlinger-Wilke C, Wilke HJ.   +7 more
europepmc   +1 more source