Results 131 to 140 of about 63,884 (240)

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu   +2 more
wiley   +1 more source

Intracellular mechanosensation in intestinal smooth muscle: Piezo1 complexes amplify signalling beyond the surface

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mechanosensation is not confined to the cell surface. In intestinal smooth muscle Piezo1 is predominantly intracellular (86%), where it forms a nanoscale (<40 nm) complex at the sarcoplasmic reticulum (SR)–plasma membrane junction. Within this sensor–amplifier–effector axis intra‐Piezo1 is the sensor that detects force at the SR,
Geoanna M. Bautista   +11 more
wiley   +1 more source

Pathogenic Variants in HEPACAM Alter Protein Localization and Interactome in Astrocytes of the Developing Mouse Cortex

open access: yesGlia, Volume 74, Issue 11, November 2026.
Pathogenic variants alter hepaCAM protein distribution. Astrocyte‐specific hepaCAM TurboID reveals KCNQ2 as a new interaction partner. Pathogenic variants alter hepaCAM association with key transmembrane proteins. ABSTRACT Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy characterized by early‐onset macrocephaly,
Robert W. Lewis   +10 more
wiley   +1 more source

Über die Verdauung von rohem Hühnereiweiß durch Papain

open access: yes, 1907
ÜBER DIE VERDAUUNG VON ROHEM HÜHNEREIWEISS DURCH PAPAIN Details: Zeitschrift für physiologische Chemie: 1.1877-20.1895 Hoppe-Seyler's Zeitschrift für physiologische Chemie: 21.1895- 112.1921 (-) Hoppe-Seyler's Zeitschrift für Physiologische ...
Sachs, Fritz
core   +1 more source

PENGGUNAAN ENZIM PAPAIN TERHADAP EFISIENSI, KONVERSI PAKAN DAN PERTUMBUHAN BENIH IKAN KEURELING(TOR TAMBRA) [PDF]

open access: yes, 2015
The objective of this research was to determine the optimum dose of papain in feed on feeding efficiency and growth of Tor tambra juvenile. The measured variables were absolute growth rate, specific growth, daily growth, survival rate, feeding efficiency,
fardin aprido
core  

Müller Glia Subtypes Define Neuro‐Glial Associations and Spatial Morphogen Axes in the Zebrafish Retina

open access: yesGlia, Volume 74, Issue 11, November 2026.
Zebrafish Müller glia are heterogeneous in the early larval retina. Zebrafish Müller glia subtypes define a spatial axis of retinoic acid metabolism. Neuron‐associated glial programs identified in Zebrafish Müller glia are evolutionarily conserved in mammals. ABSTRACT Müller glia are instrumental macroglia of the vertebrate retina, once thought to be a
Samuel S. Storey   +3 more
wiley   +1 more source

Immunomodulatory, Antifatigue, and Hypoxia Tolerance Effects of Polygonatum cirrhifolium Polysaccharides: Structural Characterization and MAPK/NF‐κB Pathway Insights

open access: yesStarch - Stärke, Volume 78, Issue 11, November 2026.
This study provides evidence that Polygonatum cirrhifolium polysaccharides possesses significant immunomodulatory, antifatigue, and hypoxia‐tolerance effects. The findings suggest that the MAPK/NF‐κB signaling pathway may be involved in its immunoregulatory actions and that PCP could be a promising candidate for enhancing physical performance and ...
Jun Nan   +4 more
wiley   +1 more source

Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis

open access: yesAngewandte Chemie, Volume 138, Issue 44, 26 October 2026.
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi   +6 more
wiley   +2 more sources

Cereal Biomass Valorization for Functional Food Ingredients: Fractionation and Circular Biorefinery Strategies

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Food processing must transition toward resource‐efficient systems that operate within planetary boundaries. Cereals, as climate‐resilient staples, offer strong potential to valorize nutrient‐rich fractions. Zero‐waste biorefinery concepts and green fractionation technologies, integrated with structure–function principles, enable the conversion
Rahul Biswas   +5 more
wiley   +1 more source

A nanobiotechnological approach to control non‐persistent aphid‐transmitted plant viruses, based on functionalized virus‐like particles

open access: yesAnnals of Applied Biology, Volume 189, Issue 3, November 2026.
A potyvirus‐derived virus‐like nanoparticle (VLP) interferes in the transmission by aphids of the non‐circulative plant viruses turnip mosaic virus (TuMV, Potyvirus), zucchini yellow mosaic virus (ZYMV, Potyvirus), and cucumber mosaic virus (CMV, Cucumovirus) is also observed. The construct, that consisted of a fusion between a modified TuMV HC‐Pro and
Aranzazu Moreno   +7 more
wiley   +1 more source

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