Results 51 to 60 of about 51,627 (231)

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

Efektivitas Pemberian Papain Getah Pepaya Terhadap Kadar Faktor Pertumbuhan Transforming Growth Factor -Β (Tgf-Β) pada Proses Penyembuhan Luka Bakar Tikus Percobaan

Jurnal Kesehatan Andalas, 2019
Pengobatan untuk luka bakar dengan menggunakan bahan alam sudah dilakukan, diantaranya madu lebah, lidah buaya dan papain. Papain merupakan enzim yang ditemukan pada getah papaya.
Gusti Revilla
doaj   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

DETERMINATION of OPTIMUM CONDITION of PAPAIN ENZYME FROM PAPAYA VAR JAVA (Carica papaya )

Indonesian Journal of Chemistry, 2010
A study to investigate the optimum condition of papain enzyme has been carried out. The condition that are investigated are pH and temperature, based on measurement of enzyme activity which is defined as mmole tyrosin that are released in reaction ...
Aline Puspita Kusumadjaja, Rita Puspa Dewi   +1 more
doaj   +1 more source

Utilization of baker's yeast (Saccharomyces cerevisiae) for the production of yeast extract: Effects of different enzymatic treatments on solid, protein and carbohydrate recovery [PDF]

Journal of the Serbian Chemical Society, 2007
Yeast extract (YE) was produced from commercial pressed baker's yeast (active and inactivated) using two enzymes: papain and lyticase. The effects of enzyme concentration and hydrolysis time on the recovery of solid, protein and carbohydrate were ...
Vukašinović-Milić Tatjana, Rakin Marica, Šiler-Marinković Slavica   +2 more
doaj   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Differences between cultured cortical neurons by trypsin and papain digestion

Ibrain, 2022
The objective of this study was to compare the efficiency of trypsin and papain in neuronal digestion and determine which enzyme is more efficient. Cortical tissues were obtained from Sprague–Dawley (SD) rats. According to the different digestive enzymes,
Chang‐Yan Hu, Ruo‐Lan Du, Qiu‐Xia Xiao, Min‐Jian Geng   +3 more
doaj   +1 more source

Protease‐Triggered Chromogenic Release From Peptide‐Modified Calcium Carbonate Microspheres Enables Colorimetric Detection of Porphyromonas gingivalis Activity

Advanced Science, EarlyView.
We report a chromogenic release‐based assay system with protease‐cleavage peptide‐modified calcium carbonate microspheres for colorimetric detection of Porphyromonas (P.) gingivalis activity. In response to Arg‐specific gingipain secreted by P. gingivalis, the supernatant becomes colored, enabling colorimetric analysis and providing the monitoring of ...
Yuki Hiruta, Zhicheng Jin, Mari Adachi, Lubna Amer, Natalia O. Tjokro, Diego F. Trujillo, Jan Potempa, Anthony J. O'Donoghue, Casey Chen, Jesse V. Jokerst   +9 more
wiley   +1 more source

Isolation and Characterization of Papain From The Latex of Papaya (Carica papaya L)

Indonesian Journal of Chemical Research, 2015
The papain enzyme was isolated from the latex of papaya and it was purified by ammonium sulfat fractionation and dialysis methods. Determination of papain enzyme activity showed that the highest activity was found in the 80% fraction with a specific ...
Dominggus Malle, Ivonne Tellusa, Astrid A. Lasamahu   +2 more
doaj  

Papain Covalently Immobilized on Chitosan–Clay Nanocomposite Films: Application in Synthetic and Real White Wine

Nanomaterials, 2020
Increasing attention has been recently paid to the development of nanocomposite materials for food application as new tool to enhance the mechanical and thermal properties of polymers.
Ilaria Benucci, Claudio Lombardelli, Ilaria Cacciotti, Marco Esti   +3 more
doaj   +1 more source