Results 41 to 50 of about 63,884 (240)

Pengaruh Dosis Enzim Papain terhadap Rendemen dan Kualitas Virgin Coconut Oil (VCO)

Jurnal Agro Industri Perkebunan, 2015
Virgin Coconut Oil (VCO) is the coconut oil that is produced naturally without chemicals and heating process. Papain enzyme is a protease that is used in the fermentation of milk serves as a catalyst in the manufacture of the VCO.
Ahmat Iskandar, Ersan Ersan, Rachmad Edison   +2 more
doaj   +1 more source

The effect of salts upon the pH dependence of the activity of papain and succinyl-papain

, 1972
Papain (EC 3.4.4.10) and succinyl-papain exhibit isoelectric points of 9.6 and 4.3, respectively. The acid limb of the pH activity curve in the pH range of 3.5–4.5 of native papain and the basic limb in the pH range of 8–9 of succinyl-papain are shifted ...
Graaf, de, M.J.M., Sluyterman, L.A.A.E.
core   +1 more source

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

Advanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang, Tsz Kwan Yau, Joyce Tse, Tsz Ho Li, Dongjie Hu, Yong Juan Zhao, Ting‐Fung Chan   +6 more
wiley   +1 more source

Physical, Microbial, and Chemical Qualities of Dangke Produced by Different Temperatures and Papain Concentrations

Media Peternakan, 2017
Dangke, a dairy product of cow or buffalo, is a traditional food of Enrekang, South Sulawesi Province. Addition of papain in dangke preparation is responsible for the formation of solid texture of dangke.
Andi Nurul Mukhlisah, Irma Isnafia Arief, Epi Taufik   +2 more
doaj   +1 more source

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Papain-papaya protein interactions : resistance of papaya protein to proteolytic digestion by papain [PDF]

, 1970
The proteolytic actjvity of papain was investigated with respect to its action on both natural substrates (native papaya protein and bovine serum albumin) and artificial synthetic substrate (benzoyl~l-arginine ethyl ester).
Rudy, John Leonard
core  

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

Advanced Science, EarlyView.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han, Lintao Wang, Xin Zhong, Shenggang Zhao, Huihui Xie, Xue Han, Liming Lin, Yiting Lyu, Ke Xu, Jiajun Xu, Xiaowen Shi   +10 more
wiley   +1 more source

Biogenic Synthesis of Papain Conjugated Copper Metallic Nanoparticles and Its Antibacterial and Antifungal Activity [PDF]

Iranian Journal of Materials Science and Engineering
Biogenic synthesis of papain-conjugated copper metallic Nanoparticles and their antibacterial and antifungal activities Papain metallic conjugated nanoparticles (Papain-CuNPs) were synthesised using Papain and CuSO4.5H2O.
Muddukrishnaiah Kotakonda, Sajisha V.S, Aiswarya G, Safeela Nasrin Pakkiyan, Najamol A Alungal, Mayoora Kiliyankandi K, Divya Thekke Kareth, Naheeda Ashraf Verali Parambil, Saranya Sasi Mohan, Renjini Anil Sheeba, Sarika Puthiya Veettil, Dhanish Joseph, Nishad Kakkattummal, Afsal Bin Haleem MP, Safeera Mayyeri, Thasneem Chemban Koyilott, Nasiya Nalakath, Samuel Thavamani B, Famila Rani J, Aruna Periyasamy, Chellappa V Rajesh, Rameswari Shanmugam, Marimuthu Poornima, Tina Raju, Roshni E R, Sirajudheen Mukriyan Kallungal, Lekshmi MS Panicker, Saranya K G, Shilpa V P   +28 more
doaj  

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee, Gayeon Kim, Ellison R. Black, Seonil Kim   +3 more
wiley   +1 more source