Results 21 to 30 of about 51,627 (231)

Semi-Solid Pharmaceutical Formulations for the Delivery of Papain Nanoparticles

Pharmaceutics, 2020
Papain is a therapeutic enzyme with restricted applications due to associated allergenic reactions. Papain nanoparticles have shown to be safe for biomedical use, although a method for proper drug loading and release remains to be developed.
Caroline S. A. de Lima, Justine P. R. O. Varca, Kamila M. Nogueira, Gabriela N. Fazolin, Lucas F. de Freitas, Eliseu W. de Souza, Ademar B. Lugão, Gustavo. H. C. Varca   +7 more
doaj   +1 more source

Growth and survival of catfish (Clarias gariepinus) with addition of papain enzymes in feed at Karang Dapo Village, Pagaralam, South Sumatera

Acta Aquatica, 2022
Catfish (Clarias gariepinus) is a freshwater fish that is widely cultivated in Indonesia. Production cost of fish farming activities spend 60-70% on the use of feed.
Alni Nuraisyah, Retno Cahya Mukti
doaj   +1 more source

Crystal structure of MOA in complex with a peptide fragment: A protease caught in flagranti

Current Research in Structural Biology, 2020
The Marasmius oreades agglutinin (MOA) is the holotype of an emerging family of fungal chimerolectins and an active Ca2+/Mn2+-dependent protease, which exhibits a unique papain-like fold with special active site features.
Dipankar Manna, Gabriele Cordara, Ute Krengel   +2 more
doaj   +1 more source

Increasing the Yield and Cryosurvival of Spermatozoa from Rhinoceros Ejaculates Using the Enzyme Papain

Biology, 2022
The preservation of rhinoceros semen is vital for captive breeding programs. While successful collection and cryopreservation of rhinoceros semen has been reported, the volume and quality of semen produced is often low due to the high viscosity ...
Jessica P. Rickard, Kelsey Pool, Simon P. de Graaf, Timothy Portas, Natalie Rourke, Miriam Wiesner, Thomas B. Hildebrandt, Frank Göritz, Robert Hermes   +8 more
doaj   +1 more source

PEMURNIAN PARSIAL DAN KRISTALISASI PAPAIN DARI GETAH Carica papaya

Jurnal Kimia Riset, 2019
This research has done partial purification by fractionation and optimization crystallization of papain from Carica papaya latex with the addition of ammonium sulphate. The enhancement of purification factor was determined by its specific activity.
Dwi Putri Mashfufatur Rohmah, Sofijan Hadi, Afaf Baktir   +2 more
doaj   +1 more source

Penggunaan enzim papain untuk meningkatkan pemanfaatan protein pakan ikan tambakan (Helostoma temminckii)

Acta Aquatica, 2022
The aim of this research was to determine of optimum dosage of papain enzyme in feed for kissing gourami. This research used Completely Randomized Design non-factorial, consist of four treatments and three replications, namely: P0 (wihout papain ...
Yulisman Yulisman, Mohamad Amin, Retno Cahya Mukti, Nurcheni Astara   +3 more
doaj   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

Advanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang, Yi‐Ke Lin, Wei‐Li Chen, Ta‐Ching Chen, Jiashing Yu   +4 more
wiley   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Papain expression in the Escherichia coli cytoplasm by T7-promoter engineering and co-expression with human protein disulfide isomerase (PDI) and thiol peroxidase (GPx7) genes

Applied and Environmental Microbiology
Difficulties exist in obtaining full-length, correctly folded, and soluble papain or papain-like proteases that necessitate the exploration of alternative strategies. This study describes the development of an Escherichia coli strain capable of producing
Md Anarul Hoque, Richard A. Gross, Mattheos A. G. Koffas   +2 more
doaj   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source