Results 61 to 70 of about 108,628 (305)

c-Rel Is Required for IL-33-Dependent Activation of ILC2s

Frontiers in Immunology, 2021
Group 2 innate lymphoid cells (ILC2s) are emerging as important cellular regulators of homeostatic and disease-associated immune processes. The cytokine interleukin-33 (IL-33) promotes ILC2-dependent inflammation and immunity, with IL-33 having been ...
Aidil Zaini, Aidil Zaini, Thomas S. Fulford, Raelene J. Grumont, Raelene J. Grumont, Jessica Runting, Jessica Runting, Grace Rodrigues, Grace Rodrigues, Judy Ng, Judy Ng, Steve Gerondakis, Steve Gerondakis, Colby Zaph, Colby Zaph, Sebastian Scheer, Sebastian Scheer   +16 more
doaj   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

Advanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang, Myungji Kim, Hwanyong Choi, Jinseon Park, Minji Kim, Donghwan Kim, Bo Ram Lee, Jinah Jang   +7 more
wiley   +1 more source

Physical, Microbial, and Chemical Qualities of Dangke Produced by Different Temperatures and Papain Concentrations

Media Peternakan, 2017
Dangke, a dairy product of cow or buffalo, is a traditional food of Enrekang, South Sulawesi Province. Addition of papain in dangke preparation is responsible for the formation of solid texture of dangke.
Andi Nurul Mukhlisah, Irma Isnafia Arief, Epi Taufik   +2 more
doaj   +1 more source

Purification and in situ immobilization of papain with aqueous two-phase system. [PDF]

PLoS ONE, 2010
Papain was purified from spray-dried Carica papaya latex using aqueous two-phase system (ATPS). Then it was recovered from PEG phase by in situ immobilization or preparing cross-linked enzyme aggregates (CLEAs). The Plackett-Burman design and the central
Mingliang Li, Erzheng Su, Pengyong You, Xiangyu Gong, Ming Sun, Diansheng Xu, Dongzhi Wei   +6 more
doaj   +1 more source

In Search of Antioxidant Peptides from Porcine Liver Hydrolysates Using Analytical and Peptidomic Approach

Antioxidants, 2021
The search for antioxidant peptides as health-promoting agents is of great scientific interest for their biotechnological applications. Thus, the main goal of this study was to identify antioxidant peptides from pork liver using alcalase, bromelain ...
María López-Pedrouso, José M. Lorenzo, Paula Borrajo, Daniel Franco   +3 more
doaj   +1 more source

Molecular docking of potential SARS-CoV-2 papain-like protease inhibitors

Biochemical and Biophysical Research Communications - BBRC, 2020
SARS-CoV-2 papain-like protease is considered as an important potential target for anti-SARS-CoV-2 drug discovery due to its crucial roles in viral spread and innate immunity. Here, we have utilized an in silico molecular docking approach to identify the
Daoqun Li, Junwen Luan, Leiliang Zhang
semanticscholar   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Current-Volt Biosensing “Cystatin C” on Carbon Nanowired Interdigitated Electrode Surface: A Clinical Marker Analysis for Bulged Aorta

Journal of Analytical Methods in Chemistry, 2022
A carbon nanowire-modified surface with interdigitated electrode (IDE) sensing system was introduced to identify abdominal aortic aneurysm biomarker “papain,” also known as cysteine protease, used as the capture probe to identify Cystatin C.
Xi Chen, Jie Kang, Qiu Sun, Cheng Liu, Hongling Wang, Chen Wang, Subash C. B. Gopinath   +6 more
doaj   +1 more source

Bio-Inspired Amphiphilic Block-Copolymers Based on Synthetic Glycopolymer and Poly(Amino Acid) as Potential Drug Delivery Systems [PDF]

, 2020
In this work, a method to prepare hybrid amphiphilic block copolymers consisting of biocompatible synthetic glycopolymer with non-degradable backbone and biodegradable poly(amino acid) (PAA) was developed.
Dobrodumov, Anatoliy, Kashina, Anna, Korzhikova-Vlakh, Evgenia, Lavrentieva, Antonina, Levit, Mariia, Rühl, Eckart, Scheper, Thomas, Tennikova, Tatiana, Vdovchenko, Alena, Zakharova, Natalya, Zashikhina, Natalia   +10 more
core   +1 more source