Results 71 to 80 of about 108,628 (305)

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Biogenic Synthesis of Papain Conjugated Copper Metallic Nanoparticles and Its Antibacterial and Antifungal Activity [PDF]

Iranian Journal of Materials Science and Engineering
Biogenic synthesis of papain-conjugated copper metallic Nanoparticles and their antibacterial and antifungal activities Papain metallic conjugated nanoparticles (Papain-CuNPs) were synthesised using Papain and CuSO4.5H2O.
Muddukrishnaiah Kotakonda, Sajisha V.S, Aiswarya G, Safeela Nasrin Pakkiyan, Najamol A Alungal, Mayoora Kiliyankandi K, Divya Thekke Kareth, Naheeda Ashraf Verali Parambil, Saranya Sasi Mohan, Renjini Anil Sheeba, Sarika Puthiya Veettil, Dhanish Joseph, Nishad Kakkattummal, Afsal Bin Haleem MP, Safeera Mayyeri, Thasneem Chemban Koyilott, Nasiya Nalakath, Samuel Thavamani B, Famila Rani J, Aruna Periyasamy, Chellappa V Rajesh, Rameswari Shanmugam, Marimuthu Poornima, Tina Raju, Roshni E R, Sirajudheen Mukriyan Kallungal, Lekshmi MS Panicker, Saranya K G, Shilpa V P   +28 more
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LAMA PEMBERSIHAN EFISIEN PAPAIN PADA PENGLEPASAN PLAK GIGITIRUAN

Journal of Dentistry Indonesia, 2015
Everyday denture cleaning is needed to prevent the mouth from denture stomatitis and esthetic concern. Enzyme cleansers are developed in attempt to break down the organic components of denture plaque.
Siti Sunarintyas
doaj   +1 more source

Sterilization of lung matrices by supercritical carbon dioxide [PDF]

, 2016
Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression
Balestrini, Jenna L, Blatt, Kelly M S, Broekelmann, Tom J, Gard, Ashley L, Huie, Janet, Liu, Angela, Mecham, Robert P, Niklason, Laura E, Schwan, Jonas, Wilcox, Elise C, Zhao, Liping   +10 more
core   +2 more sources

Study on industrial applications of papain: A succinct review

IOP Conference Series: Earth and Environment, 2020
Papain is an enzyme having proteolytic function with cysteine protease activity obtain from papaya having green color and is acquired from latex. It is classified in superfamily.
H A Shouket, I. Ameen, O. Tursunov, Kh Kholikova, O. Pirimov, N. Kurbonov, I. Ibragimov, B. Mukimov   +7 more
semanticscholar   +1 more source

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

The use of phenyl-Sepharose for the affinity purification of proteinases [PDF]

, 1993
Phenyl-Sepharose is most often used as an adsorbent for hydrophobic interaction chromatography (HIC). We report on its effective use for the affinity purification of some extracellular thermostable proteinases from bacterial sources.
Daniel, Roy M., Peek, Keith, Prescott, Mark, Veitch, Dallas P.   +3 more
core   +2 more sources

Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes

Antiviral Research, 2017
Severe acute respiratory syndrome coronavirus (SARS‐CoV) emerged in southern China in late 2002 and caused a global outbreak with a fatality rate around 10% in 2003.
Min-Han Lin, David C Moses, Chih-Hua Hsieh, Shu‐Chun Cheng, Yau-Hung Chen, Chiao-Yin Sun, C. Chou   +6 more
semanticscholar   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Extraction, identification and activity of Papain from Iran [PDF]

Journal of Mazandaran University of Medical Sciences, 2006
Background and purpose: Papain, a proteolytic enzyme, is found in the dried and purified latex from the fruits of Carica papaya L. (Caricaceae).Papain is used in medicine as a digestive and in the debridement of necrotic tissues.
M.H. Tabaei, M. Azadbakht, H. Kivani
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