Results 81 to 90 of about 49,790 (302)

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Choana Morphogenesis in Developmental Stages of Muscovy Ducks

SVU-International Journal of Veterinary Sciences, 2019
This study was performed by using Fourty nine Muscovy ducks to obtain enough information about the development of the choanal slit from 1 to 60 days old.
Fatma Madkour , Kamal Abdalla, Salma Mohamed   +2 more
doaj   +1 more source

Gαi1/3 Are Essential for BMP2‐Induced Osteogenesis by Bridging BMP Receptors to the Gab1 Signaling Complex

Advanced Science, EarlyView.
The Gαi1/3 protein is a crucial connecting protein closely related to the signal transduction process of bone formation‐related cytokines such as BMP2. Gαi1/3 mediates downstream signaling pathways such as Smads and MAPK by binding to adaptor proteins like Gab1, thereby promoting the osteogenic effect of BMSCs.
Huajian Shan, Chaowen Bai, Yifei Zhu, Chenyang Xu, Sonngtao Li, Qize Sun, Chang She, Jinyu Bai, Cong Cao, Yitian Yang, Xiaozhong Zhou   +10 more
wiley   +1 more source

Peeling and aspiration of elschnig pearls! An effective alternative to Nd:YAG laser capsulotomy!

Indian Journal of Ophthalmology, 2013
To evaluate the efficacy of peeling and aspiration of Elschnig pearls. Retrospective study in a medical college hospital. Records of 217 eyes which underwent surgical peeling and aspiration for membranous PCO between 2006 and 2009, was reviewed.
Rahul Bhargava, Prachi Kumar, Shiv K Sharma, Sumat Sharma, Namrata Mehra, Anuraag Mishra   +5 more
doaj   +1 more source

Connective tissue grafts with nonincised papillae surgical approach for periodontal reconstruction in noncontained defects [PDF]

, 2019
© 2019 Quintessence Publishing Co Inc. This document is the Published, version of a Published Work that appeared in final form in International Journal of Periodontics & Restorative Dentistry .
Ortiz Ruiz, Antonio José, Pecci Lloret, Miguel, Pardo Zamora, Guillermo, Moreno Rodríguez, José Antonio, Caffesse, Raúl G.   +4 more
core   +1 more source

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

Advanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He, Hejun Ren, Shuo Zhang, Jikang Cheng, Hui Zhang, Jiao Liu, Sijie Wang, Congfen Gao, Yanchao Zhang, Yunhao Gao   +9 more
wiley   +1 more source

Regional regulation of Filiform tongue papillae development by Ikkα/Irf6

, 2016
BACKGROUND: Non-gustatory filiform papillae play critical roles in helping to grip food, drawing food to the esophagus, cleaning the mouth, and spreading saliva.
Oommen, S., Maeda, Takeyasu, Nagai, T., Hammond, Nigel; id_orcid, Ohazama, Atsushi, Oommen, Shelly, Ohazama, A., Inoue, Jun Ichiro, James Blackburn, Momoko Watanabe, Nagai, Takahiro, Sharpe, Paul T, Jun‐Ichiro Inoue, Liu, B., Hammond, Nigel L., Katsushige Kawasaki, Bigang Liu, Maiko Kawasaki, Kitamura, A., Watanabe, M., Ruth Schmidt‐Ullrich, Atsushi Kitamura, Inoue, J.I., Atsushi Ohazama, Kawasaki, Maiko, Kawasaki, Katsushige, Akiyama, T., Paul T. Sharpe, Sharpe, P.T., Blackburn, James, Nigel L. Hammond, Schmidt-Ullrich, R., Taishin Akiyama, Hammond, N.L., Kitamura, Atsushi, Sharpe, Paul T., Watanabe, Momoko, Inoue, Jun-Ichiro, Shelly Oommen, Takeyasu Maeda, Maeda, T., Schmidt-Ullrich, Ruth, Takahiro Nagai, Liu, Bigang, Akiyama, Taishin, Kawasaki, K., Kawasaki, M., Blackburn, J.   +47 more
core   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Micromorphology and histochemical traits of staminal osmophores in Asphodelus aestivus Brot. flower

Acta Agrobotanica, 2012
The conducted studies pertained to micromorphology of the surface of epidermis cells and histological traits of staminal filaments of Asphodelus aestivus Brot. flowers.
Elżbieta Weryszko-Chmielewska, Mirosława Chwil, Thomas Sawidis   +2 more
doaj   +1 more source