Results 81 to 90 of about 16,162 (223)
The Role of Viruses in the Pathogenesis of Periodontitis
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte +2 more
wiley +1 more source
Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng +3 more
wiley +1 more source
Background The E6 and E7 proteins in human papillomavirus 16 (HPV 16) are the main oncogenes in the occurrence of lung cancer. In recent studies, we found that E6 and E7 downregulated the expression of LKB1 in lung cancer cells.
Yue Hu +5 more
doaj +1 more source
Spontaneous regression of equine sarcoids is an exceptional event
Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley +1 more source
The human papillomavirus E7 oncoprotein
The human papillomavirus (HPV) E7 oncoprotein shares functional similarities with such proteins as adenovirus E1A and SV40 large tumor antigen. As one of only two viral proteins always expressed in HPV-associated cancers, E7 plays a central role in both ...
McLaughlin-Drubin, Margaret E. +1 more
core +1 more source
Background Persistent infection with high-risk Human Papillomavirus (HPVs) is associated with the development of cervical cancer. The transforming capacity of these viruses relies on the cooperative action of the E6 and E7 viral oncoproteins.
María Paula Dizanzo +6 more
doaj +1 more source
ABSTRACT High‐risk human papillomaviruses (HPV) are the main etiological agents of cervical cancer. The viral early promoter regulates the expression of E6/E7 oncoproteins, and its transcriptional activity is positively or negatively regulated by host transcription factors (TFs) that are able to bind to the viral long control region (LCR).
Valéria Talpe‐Nunes +11 more
wiley +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Improved immunodetection of human papillomavirus E7
Human papillomavirus E7 (HPV E7) is a viral oncoprotein that plays an important role in cervical carcinogenesis through binding with retinoblastoma protein (Rb).
Kwon, JC +6 more
core +1 more source

