Differences in intestinal size, structure, and function contributing to feed efficiency in broiler chickens reared at geographically distant locations [PDF]
, 2019 The contribution of the intestinal tract to differences in residual feed intake (RFI) has been inconclusively studied in chickens so far. It is also not clear if RFI-related differences in intestinal function are similar in chickens raised in different ...
Aschenbach, J. +9 more
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT IgA nephropathy (IgAN), the most common form of glomerulonephritis, is a major and growing public health issue. It results from intestinal barrier dysfunction that leads to mesangial deposition of pathogenic galactose‐deficient IgA1 (Gd‐IgA1) and renal inflammation.
Meng‐Si Li, Kai Liu
wiley +1 more source
Testing the relationship between gut permeability, elevation of systemic lipopolysaccharides and chronic disease : A thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy at Massey University, Manawatu, New Zealand [PDF]
, 2016 The aim of my thesis was to test whether an increase in the permeability of the gut is accompanied by an increase in the level of systemic lipopolysaccharides (LPS), also referred to as endotoxin.
Gnauck, Anne
core
Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity. [PDF]
, 2018 Polarization of the airway epithelial cells (AECs) in the airway lumen is critical to the proper function of the mucociliary escalator and maintenance of lung health, but the cellular requirements for polarization of AECs are poorly understood.
Fahy, John V +8 more
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The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley +1 more source
Acta Pharmaceutica Sinica BThe blood–brain barrier (BBB) is a crucial biological interface between the central nervous system and circulation, playing a key role in maintaining the brain's homeostasis and function, but presenting a challenge for drug delivery.
Junrong Wu +8 more
doaj +1 more source
Inflammatory Responses and Barrier Function of Endothelial Cells Derived from Human Induced Pluripotent Stem Cells [PDF]
, 2018 Several studies have reported endothelial cell (EC) derivation from human induced pluripotent stem cells (hiPSCs). However, few have explored their functional properties in depth with respect to line-to-line and batch-to-batch variability and how they ...
Freund, Christian +6 more
core +3 more sources
Paracellular and transcellular pathways facilitate insulin permeability in rat gut
Journal of Pharmacy and Pharmacology, 2006 AbstractThe aim of this study was to conduct a systematic investigation of the absorption of insulin in the rat intestine in the presence of permeation enhancers and protease inhibitors. An in-situ perfused rat gut model was used for the co-perfusion of insulin and PEG 4000 in the presence or absence of bile salts, bile salt:fatty acid surfactant ...
Majella E, Lane, Owen I, Corrigan
openaire +2 more sources
The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis
Phytotherapy Research, EarlyView.ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang +7 more
wiley +1 more source
Blood-brain barrier tight junction permeability and ischemic stroke
Neurobiology of Disease, 2008 The blood-brain barrier (BBB) is formed by the endothelial cells of cerebral microvessels, providing a dynamic interface between the peripheral circulation and the central nervous system.
Karin E. Sandoval, Ken A. Witt
doaj +1 more source