Results 131 to 140 of about 41,666 (255)

Effects of Algae β‐Glucan Supplementation on the Performance and Intestinal Immune System of Healthy Weaned Piglets

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT While β‐glucans from plants and yeasts have been extensively studied in weaned piglets, studies examining algae β‐glucans are scarce. Thus, the present study aimed to examine the effects of feeding algae β‐glucan in weaned piglets. Male, 21‐day‐old, weaned crossbred piglets were allotted to three experimental groups, which were fed either an ...
Johanna O. Buckenberger, Felizitas Gutöhrlein, Manfred Henrich, Erika Most, Rose Whelan, John K. Htoo, Robert Ringseis, Klaus Eder   +7 more
wiley   +1 more source

Antidiarrheal Action of Bacillus subtilis CU1 CNCM I-2745 and Lactobacillus plantarum CNCM I-4547 in Mice

Frontiers in Microbiology, 2018
Preventive actions of probiotics as antidiarrheal agents are well documented, but their mechanisms are poorly understood. Two selected probiotics, Bacillus subtilis CU1 and Lactobacillus plantarum CNCM I-4547, were tested in mouse experimental models of ...
Maria C. Urdaci, Marie Lefevre, Guylene Lafforgue, Guylene Lafforgue, Christel Cartier, Christel Cartier, Bertrand Rodriguez, Jean Fioramonti, Jean Fioramonti   +8 more
doaj   +1 more source

Current and evolving approaches for improving the oral permeability of BCS Class III or analogous molecules [PDF]

, 2016
The Biopharmaceutics Classification System (BCS) classifies pharmaceutical compounds based on their aqueous solubility and intestinal permeability. The BCS Class III compounds are hydrophilic molecules (high aqueous solubility) with low permeability ...
Dave, Vivek S, Gupta, Deepak, Gupta, Sheeba Varghese, Nguyen, Phong, Yu, Monica   +4 more
core   +2 more sources

Low-Salt Diet Induces Claudin-3 Expression and Drives Adaptive Changes in Collecting Duct of Claudin-3-Deficient Mice. [PDF]

Acta Physiol (Oxf)
ABSTRACT Aim Renal sodium reabsorption occurs through both transcellular and paracellular pathways. Tight junction proteins play a key role in mediating paracellular transport. The collecting duct is critical for the fine tuning of sodium balance and is highly responsive to changes in dietary salt intake.
Sassi A, Chassot A, Jellali S, Liaudet N, Polat A, Baier F, Stroka D, Furuse M, Feraille E.   +8 more
europepmc   +2 more sources

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

Periodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens, Ekin Yay‐Kus, Rafael Scaf de Molon, Viorelia Stoica, Peter Rimmer, Josefine Hirschfeld, Asif Jilani Iqbal, Tariq Iqbal, Iain Chapple   +8 more
wiley   +1 more source

Th17 Cytokines Disrupt the Airway Mucosal Barrier in Chronic Rhinosinusitis

Mediators of Inflammation, 2016
Cytokine mediated changes in paracellular permeability contribute to a multitude of pathological conditions including chronic rhinosinusitis (CRS). The purpose of this study was to investigate the effect of interferons and of Th1, Th2, and Th17 cytokines
Mahnaz Ramezanpour, Sophia Moraitis, Jason L. P. Smith, P. J. Wormald, Sarah Vreugde   +4 more
doaj   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Acute psychological stress increases paracellular permeability and modulates immune activity in rectal mucosa of healthy volunteers. [PDF]

United European Gastroenterol J, 2023
Gerdin L, González-Castro AM, Ericson AC, Persborn M, Santos J, Walter SA, Keita ÅV, Vicario M, Söderholm JD.   +8 more
europepmc   +1 more source

MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model

The Journal of Physiology, EarlyView.
Abstract figure legend Propionate in the fetal circulation is thought to originate from fermentation of dietary fibre by the maternal gut microbiota. However, the mechanism of transplacental transport has remained unclear. Here, we measured propionate permeability using a placental barrier model generated by differentiating human placental trophoblast ...
Toshiaki Tsuchitani, Rin Midorikawa, Akari Kasuya, Saki Noguchi, Kohei Yamamoto, Tomohiro Nishimura, Hirokazu Kaji, Takeshi Hori, Masatoshi Tomi   +8 more
wiley   +1 more source