Results 171 to 180 of about 666,834 (274)

Inhibition of retinoid X receptor improved the morphology, localization of desmosomal proteins and paracellular permeability in three-dimensional cultures of mouse keratinocytes. [PDF]

Microscopy (Oxf), 2022
Ishikawa S, Nikaido M, Otani T, Ogata K, Iida H, Inai Y, Tamaoki S, Inai T.   +7 more
europepmc   +1 more source

Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption

Obesity Reviews, Volume 27, Issue 4, April 2026.
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg, Andrea Edginton, Matthew D. Jones, Nikoletta Fotaki   +3 more
wiley   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

Experimental Physiology, Volume 111, Issue 4, Page 1733-1745, 1 April 2026.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh, Amir Arsalan Ghahari, Ehsan Zandi, Seyedeh Zeynab Rasouli, Shaghayegh Davari, Mobina Hoseinzadeh, Mir Alireza Nourazar   +6 more
wiley   +1 more source

Intestine‐Specific Expression of Human Chimeric Intestinal Alkaline Phosphatase Attenuates Western Diet‐Induced Barrier Dysfunction and Glucose Intolerance [PDF]

, 2018
Intestinal epithelial cell derived alkaline phosphatase (IAP) dephosphorylates/detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the gut lumen.
Ghosh, Shobha, Ghosh, Siddhartha S., He, Hongliang, Korzun, William, Wang, Jing, Yannie, Paul J.   +5 more
core   +1 more source

Characterizing airway epithelial cultures grown on permeable inserts with different pore densities

Physiological Reports, Volume 14, Issue 7, April 2026.
Abstract In vitro airway epithelial models, such as air‐liquid interface (ALI) cultures, are widely used for disease modeling, therapeutic and toxicology testing, and studying epithelial‐environmental interactions. However, it remains unknown whether the pore density of the permeable membrane inserts, on which primary human bronchial epithelial cells ...
T. J. F. Guo, G. K. Singhera, J. Memar Vaghri, W. Y. Liang, J. M. Leung, D. R. Dorscheid   +5 more
wiley   +1 more source

Strial capillary permeability studied with fluorescent tracers in inbred mice [PDF]

, 2015
The stria vascularis generates the endocochlear potential (EP), which relies on the maintenance of ionic boundaries. Strial and spiral ligament capillary permeability to FITC-conjugated dextrans and other tracers was assessed in mice of different strains,
Fahrenthold, Kaela Christine
core   +1 more source

Optimal timing for drug delivery into the hippocampus by focused ultrasound: A comparison of hydrophilic and lipophilic compounds

Heliyon
Aims: Previous studies have reported that focused ultrasound (FUS) helps modulate the blood-brain barrier (BBB). These studies have generally used the paracellular pathway owing to tight junction proteins (TJPs) regulation.
Younghee Seo, Kyung Won Chang, Jihyeon Lee, Chanho Kong, Jaewoo Shin, Jin Woo Chang, Young Cheol Na, Won Seok Chang   +7 more
doaj   +1 more source

Low-Dose X-Ray Increases Paracellular Permeability of Human Renal Glomerular Endothelial Cells.

Comput Math Methods Med, 2022
Wang J, Sun C, Zheng D, Sun K.
europepmc   +1 more source

Interaction between Epithelial Sodium Channel γ-Subunit and Claudin-8 Modulates Paracellular Sodium Permeability in Renal Collecting Duct.

Journal of the American Society of Nephrology, 2020
A. Sassi, Yubao Wang, Alexandra Chassot, O. Komarynets, I. Roth, V. Olivier, G. Crambert, Eva Dizin, Emilie Boscardin, E. Hummler, E. Feraille   +10 more
semanticscholar   +1 more source

Campylobacter jejuni increases the paracellular permeability of broiler chickens in a dose-dependent manner. [PDF]

Poult Sci, 2020
Awad WA, Ruhnau D, Hess C, Hess M.
europepmc   +1 more source