Results 81 to 90 of about 76,985 (314)

Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action [PDF]

Paracetamol (acetaminophen) is undoubtedly one of the most widely used drugs worldwide. As an over-the-counter medication, paracetamol is the standard and first-line treatment for fever and acute pain and is believed to remain so for many years to come ...
Ayoub, Samir
core   +1 more source

Natural South African iron‐rich sand as a functional catalyst in hybrid photocatalytic wet peroxide oxidation technology for the degradation of methyl orange dye pollutant

The Canadian Journal of Chemical Engineering, EarlyView.
This research explored South African iron‐rich sand (SAIRS) as a natural catalyst for light‐mediated wet peroxide oxidation of methyl orange dye in wastewater and at an optimized of conditions of 3500 mg/L catalyst dose, 6 mM H2O2, and pH 2.5, SAIRS achieved 94% methyl orange degradation within 90 min under visible light.
Aaliyah Ebrahim, Stephen Sunday Emmanuel, Alicia Levana Dorling, Shepherd M. Tichapondwa   +3 more
wiley   +1 more source

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries, Alastair M. Kilpatrick, Kathleen M. Scullion, Rhona Aird, Lorraine Bruce, Maria Elena Candela, Tak Yung Man, Stuart J. Forbes, James W. Dear   +8 more
wiley   +1 more source

Paracetamol self-poisoning: when oral N-acetylcysteine saves life? a case report

The Pan African Medical Journal, 2018
Paracetamol is the most widely drug involved in accidental paediatric exposures and deliberate self-poisoning cases because of its availability. N-acetyl cystein is the main treatment for this poisoning.
Said Benlamkaddem, Imane Iken, Nawfal Houari, Abderrahim Elbouazzaoui, Brahim Boukatta, Hicham Sbai, Sanae Achour, Nabil Kanjaa   +7 more
doaj   +1 more source

Paracetamol: sejauh manakah keselamatannya?

, 2016
Paracetamol (atau lebih dikenali sebagai Panadol di Malaysia) mula-mula ditemui pada tahun 1880an. Pada mulanya Paracetamol dipasarkan pada tahun 1955 sebagai ubat antipiretik (untuk meredakan demam) dan analgesik (untuk melegakan kesakitan).
Ismawi, Hidayatul Radziah
core  

Estudo clinico-epidemiológico das intoxicações por paracetamol registradas no Centro de Informações Toxicológicas de Santa Catarina no período de janeiro de 2003 a dezembro de 2010. [PDF]

, 2012
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Nesi, Rafael da Silva
core  

Exploring Cerumen as an Alternative Matrix for Drug Detection and Quantification: Method Development and Application in Clinical Samples

Drug Testing and Analysis, EarlyView.
An LC–MS/MS method was developed for the detection of 33 psychoactive medications in cerumen (earwax) and applied to the samples of 60 psychiatric inpatient volunteers. The findings highlighted the utility of cerumen as an innovative biospecimen in clinical toxicological analysis.
Dimitrios Phaedon Kevrekidis, Helen G. Gika, Georgios Panagiotoglou, Eleni Parlapani, Pavlos Pavlidis, Nikolaos Raikos   +5 more
wiley   +1 more source

RESPOSTAS MOLECULARES EM OSTRAS DO PACÍFICO Crassostrea gigas (THUNBERG 1793) EXPOSTA A PARACETAMOL [PDF]

, 2015
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Filosofia e Ciências Humanas. OceanografiaO paracetamol, analgésico mais vendido no mundo, tem sido detectado em ecossistemas aquáticos em vários países.
Mello, Alvaro Cavaler Pessoa
core  

Analgesia and side effects of codeine phosphate associated with paracetamol vs. paracetamol after the extraction of mandibular third molars: a randomized double-blind clinical trial using the split-mouth model

, 2020
Purpose: To assess the analgesia and side effects of codeine phosphate associated with paracetamol (test medication) as compared to paracetamol (control medication) after the extraction of impacted mandibular third molars.
de Carvalho, Matheus Furtado, da Silva, Yuri Slusarenko, Reher, Peter, Naclerio-Homem, Maria da Graca   +3 more
core   +1 more source

TRAIL enhances paracetamol-induced liver sinusoidal endothelial cell death in a Bim- and Bid-dependent manner [PDF]

, 2012
Paracetamol (acetaminophen, APAP) is a universally used analgesic and antipyretic agent. Considered safe at therapeutic doses, overdoses cause acute liver damage characterized by centrilobular hepatic necrosis.
Kaufmann, Thomas, Badmann, Anastasia, Keogh, Adrian, Brunner, Thomas, Corazza, Nadia, Langsch, Stephanie, Langsch, Stefanie, Langsch, S.   +7 more
core   +1 more source