Transcriptional and proteomic responses to carbon starvation in Paracoccidioides. [PDF]
BACKGROUND: The genus Paracoccidioides comprises human thermal dimorphic fungi, which cause paracoccidioidomycosis (PCM), an important mycosis in Latin America. Adaptation to environmental conditions is key to fungal survival during human host infection.
Patrícia de Sousa Lima +5 more
doaj +1 more source
Negative immunodiffusion test results obtained with sera of paracoccidioidomycosis patients may be related to low-avidity immunoglobulin G2 antibodies directed against carbohydrate epitopes [PDF]
Immunodiffusion (ID) is the serologic test most frequently used for the diagnosis and posttherapy follow-up of patients with paracoccidioidomycosis (PCM).
Blotta, Maria Heloisa SL +4 more
core +3 more sources
Climate Change, Natural Disasters, and Cutaneous Fungal Infections
ABSTRACT Fungal infections are an important source of morbidity and mortality that can manifest as superficial or invasive diseases. Diagnostic techniques for human fungal pathogens remain problematic, and multi‐drug resistance is emerging. This review addresses the potential emergence of new fungal pathogens in changing environments and reported ...
Aditya K. Gupta +2 more
wiley +1 more source
Molecular detection and identification of Paracoccidioides brasiliensis [PDF]
Nearly 800 nucleotides from the 5' terminus of the 28S ribosomal gene of Paracoccidioides brasiliensis were sequenced, and a 14-base DNA probe specific for this species was identified. Hybridization results showed that the probe identified P. brasiliensis ribosomal DNA in a panel of ribosomal DNAs representing a total of 48 species of fungi.
G S, Sandhu +3 more
openaire +2 more sources
Serology of paracoccidioidomycosis [PDF]
This review provides the background for understanding the role of a battery of diagnostic methods in paracoccidioidomycosis (PCM). This systemic mycosis is a disease endemic in many regions of Latin America, with sporadic cases also occurring throughout ...
Camargo, Zoilo Pires de
core +1 more source
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres +10 more
wiley +1 more source
Ever since the uncultivated South American fungal pathogen Lacazia loboi was first described 90 years ago, its etiology and evolutionary traits have been at the center of endless controversies.
Raquel Vilela +6 more
doaj +1 more source
Paracoccidioides brasiliensis GP43-derived peptides are potent modulators of local and systemic inflammatory response [PDF]
Paracoccidioidomycosis is a systemic granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis. Its major antigen is a 43 kDa glycoprotein whose peptides embody different functions: P10 peptide, a T-cell epitope, :induces ...
Feitosa, Luciano dos Santos +7 more
core +2 more sources
The Study of Microbial Physiology Under Microoxic Conditions Is Critical but Neglected
Microbial physiology is mainly studied under aerobic or anaerobic/anoxic conditions, neglecting microbial behaviours in diverse microoxic conditions. The current article revisits the definition of microoxia in light of recent developments in oxygen‐sensing technology and emphasises the need to understand microbial physiology and growth behaviours of ...
Om Prakash +2 more
wiley +1 more source
Gene knockdown in Paracoccidioides brasiliensis using antisense RNA [PDF]
Paracoccidioides brasiliensis is a thermal dimorphic fungus which at host environment exhibits a multinucleated and multibudding yeast form. The cellular and molecular mechanisms underlying these phenotypes remain to be clarified, mostly due to the ...
Almeida, A. J. +2 more
core +1 more source

