Results 71 to 80 of about 11,266 (199)

Paracoccidioides brasiliensis: phylogenetic and ecological aspects [PDF]

open access: yesMycopathologia, 2008
The knowledge on the biological aspects of Paracoccidioides brasiliensis has evolved greatly since the first description of the disease in 1908. From the pioneers, who were able to clearly demonstrate the fungal nature of the agent, to the recent genomic era, important advances have been achieved. P.
Bagagli, Eduardo   +3 more
openaire   +3 more sources

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez   +3 more
wiley   +1 more source

The taxonomy of two uncultivated fungal mammalian pathogens is revealed through phylogeny and population genetic analyses

open access: yesScientific Reports, 2021
Ever since the uncultivated South American fungal pathogen Lacazia loboi was first described 90 years ago, its etiology and evolutionary traits have been at the center of endless controversies.
Raquel Vilela   +6 more
doaj   +1 more source

Gene knockdown in Paracoccidioides brasiliensis using antisense RNA [PDF]

open access: yes, 2012
Paracoccidioides brasiliensis is a thermal dimorphic fungus which at host environment exhibits a multinucleated and multibudding yeast form. The cellular and molecular mechanisms underlying these phenotypes remain to be clarified, mostly due to the ...
Almeida, A. J.   +2 more
core   +1 more source

Integrated In Silico – In Vitro Study Investigating Dipeptides as Chorismate Synthase Modulators: Spotlight on Its Mechanism of Action

open access: yesGlobal Challenges, Volume 9, Issue 12, December 2025.
This study integrates computational and experimental approaches to explore how short dipeptides modulate the activity of chorismate synthase. Unexpectedly, the GluAsp dipeptide enhanced enzyme activity by promoting a transient surface channel near the active site, possibly revealing a new structural feature relevant for microbial metabolism and ...
Lorenzo Pedroni   +4 more
wiley   +1 more source

Comparative proteomics in the genus Paracoccidioides

open access: yesFungal Genetics and Biology, 2013
The genus Paracoccidioides comprises a complex of phylogenetic species of dimorphic pathogenic fungi, the etiologic agents of paracoccidioidomycosis (PCM), a disease confined to Latin America and of marked relevance in its endemic areas due to its high frequency and severity.
Pigosso, Laurine Lacerda   +6 more
openaire   +2 more sources

Fungal DNA‐barcoding on a chip: Magnetoresistive biosensors for yeast infection diagnosis

open access: yesVIEW, Volume 6, Issue 6, December 2025.
The development of a fungal pathogen identification chip is herein demonstrated. Hybridization dynamics were tested against 58 species in silico and 4 species on chip. 95% accuracy, 91% sensitivity, 98% specificity and femtomolar limit of detection were achieved. Future perspectives include the integration of sample pre‐treatment modules.
Maria Zolotareva   +8 more
wiley   +1 more source

Importance of adhesins in virulence of Paracoccidioides spp.

open access: yesFrontiers in Microbiology, 2015
Members of the Paracoccidioides genus are dimorphic fungi that are the etiologic agents of paracoccidioidomycosis (PCM). This genus is composed of two species: Paracoccidioides brasiliensis and Paracoccidioides lutzii.
Haroldo Cesar de Oliveira   +9 more
doaj   +1 more source

The Homeostasis of Iron, Copper, and Zinc in Paracoccidioides Brasiliensis, Cryptococcus Neoformans Var. Grubii, and Cryptococcus Gattii: A Comparative Analysis [PDF]

open access: yes, 2011
Iron, copper, and zinc are essential for all living organisms. Moreover, the homeostasis of these metals is vital to microorganisms during pathogenic interactions with a host.
Alexandre Melo Bailão   +14 more
core   +2 more sources

Evaluation of Caenorhabditis elegans as a host model for Paracoccidioides brasiliensis and Paracoccidioides lutzii [PDF]

open access: yesPathogens and Disease, 2018
Paracoccidioidomycosis is a systemic fungal infection affecting mainly Latin American countries that is caused by Paracoccidioides brasiliensis and Paracoccidioides lutzii. During the study of fungal pathogenesis, in vivo studies are crucial to understand the overall mechanisms involving the infection as well as to search for new therapeutic treatments
Scorzoni, Liliana   +6 more
openaire   +3 more sources

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