Results 71 to 80 of about 30,716 (258)

Infection by Histoplasma capsulatum, Cryptococcus spp. and Paracoccidioides brasiliensis in bats collected in urban areas

Transboundary and Emerging Diseases, 2018
Epidemiological studies on endemic mycosis can be improved using molecular biology techniques to elucidate the role of bats as reservoirs and vectors of pathogenic fungi for infection of other animals and humans.
G. S. da Paz, B. M. V. Adorno, V. B. Richini-Pereira, S. Bosco, H. Langoni   +4 more
semanticscholar   +1 more source

Climate Change, Natural Disasters, and Cutaneous Fungal Infections

International Journal of Dermatology, Volume 64, Issue 8, Page 1349-1355, August 2025.
ABSTRACT Fungal infections are an important source of morbidity and mortality that can manifest as superficial or invasive diseases. Diagnostic techniques for human fungal pathogens remain problematic, and multi‐drug resistance is emerging. This review addresses the potential emergence of new fungal pathogens in changing environments and reported ...
Aditya K. Gupta, Mary Thornbush, Tong Wang   +2 more
wiley   +1 more source

Promising New Antifungal Treatment Targeting Chorismate Synthase from Paracoccidioides brasiliensis

Antimicrobial Agents and Chemotherapy, 2018
Paracoccidioidomycosis (PCM), caused by Paracoccidioides, is a systemic mycosis with granulomatous character and a restricted therapeutic arsenal. The aim of this work was to search for new alternatives to treat largely neglected tropical mycosis, such ...
Franciele Abigail Vilugron Rodrigues-Vendramini, Cidnei Marschalk, M. Toplak, P. Macheroux, P. Bonfim-Mendonça, T. Svidzinski, F. Seixas, É. S. Kioshima   +7 more
semanticscholar   +1 more source

A steric gate prevents mutagenic dATP incorporation opposite 8‐oxo‐deoxyguanosine in mitochondrial DNA polymerases

The FEBS Journal, Volume 292, Issue 13, Page 3430-3448, July 2025.
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres, Carlos H. Trasviña‐Arenas, Alexandru Ionut Gilea, Upeksha C. Dissanayake, Missael Molina‐Jiménez, Paola L. García‐Medel, Corina Díaz‐Quezada, Tiziana Lodi, G. Andrés Cisneros, Enrico Baruffini, Luis G. Brieba   +10 more
wiley   +1 more source

Microdilution procedure for antifungal susceptibility testing of Paracoccidioides brasiliensis to amphotericin b and itraconazole

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
In vitro tests employing microdilution to evaluate fungal susceptibility to antifungal drugs are already standardized for fermentative yeasts. However, studies on the susceptibility of dimorphic fungi such as Paracoccidioides brasiliensis employing this ...
E Takahagi-Nakaira, MF Sugizaki, MTS Peraçoli   +2 more
doaj   +1 more source

Understanding causes of morbidity and mortality in Southern Hemisphere small Odontoceti: a scoping review

Mammal Review, Volume 55, Issue 2, April 2025.
This review identifies key causes of morbidity and mortality in Southern Hemisphere small Odontoceti, highlighting significant anthropogenic threats and the enhanced need for conservation strategies. Key findings include high rates of entanglements and a diverse range of infectious pathogens. Abstract Marine mammals serve as sentinels for environmental
Rebecca Souter, Anne‐Lise Chaber, Luciana Möller, Lucy Woolford   +3 more
wiley   +1 more source

Characterization of a Paracoccidioides spp. strain from southeastern Brazil genotyped as Paracoccidioides restrepiensis (PS3) and review of this phylogenetic species

Genetics and Molecular Biology
Phylogenetic species of Paracoccidioides brasiliensis complex (S1a and S1b, PS2, PS3, and PS4) and Paracoccidioides lutzii are agents of paracoccidioidomycosis, an endemic fungal disease in Latin America. P. restrepiensis (PS3 genotype) was classified as
Tiago Alexandre Cocio, Erika Nascimento, Marcia R. V. Z. Kress, Eduardo Bagagli, Roberto Martinez   +4 more
doaj   +1 more source

Phylogenetic Species of Paracoccidioides spp. Isolated from Clinical and Environmental Samples in a Hyperendemic Area of Paracoccidioidomycosis in Southeastern Brazil

Journal of Fungi, 2020
Paracoccidioides brasiliensis complex and P. lutzii are the etiological agents of paracoccidioidomycosis. The geographic distribution of these species in South America is still poorly comprehended. Fifty samples of Paracoccidioides spp.
Tiago A. Cocio, Erika Nascimento, Marcia R. von Zeska Kress, Eduardo Bagagli, Roberto Martinez   +4 more
doaj   +1 more source

Establishment of an experimental system to analyse extracellular vesicles during apoplastic fungal pathogenesis

Journal of Extracellular Biology, Volume 4, Issue 2, February 2025.
Abstract Phoma stem canker disease of oilseed rape (Brassica napus) is caused by the extracellular fungal pathogen Leptosphaeria maculans. Although this pathogen resides exclusively in apoplastic spaces surrounding plant cells, the significance of extracellular vesicles (EVs) has not been assessed.
Nathaniel Hearfield, Dominik Brotherton, Zedi Gao, Jameel Inal, Henrik U. Stotz   +4 more
wiley   +1 more source

Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis

Journal of Immunological Research, 2019
Paracoccidioidomycosis (PCM), a systemic mycosis endemic in Latin America, occurs after inhalation of mycelial components of Paracoccidioides spp. When the fungus reaches the lungs and interacts with the alveolar macrophages and other cells, phagocytic ...
J. C. de Quaglia e Silva, Amanda Manoel Della Coletta, T. P. Gardizani, G. Romagnoli, R. Kaneno, L. A. Dias-Melicio   +5 more
semanticscholar   +1 more source