Results 71 to 80 of about 11,427 (259)

Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses

Journal of Extracellular Biology, Volume 4, Issue 8, August 2025.
ABSTRACT Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate interactions between fungal cells and hosts, significantly influencing the pathogen‐host relationship ...
Caroline P. de Rezende, Patrick W. S. Santos, Renan A. Piraine, Virgínia C. Silvestrini, Julio C. J. Barbosa, Fabiana C. P. Valera, Edwin Tamashiro, Guilherme G. Podolski‐Gondim, Silvana M. Quintana, Rodrigo Calado, Roberto Martinez, Taicia P. Fill, Márcio L. Rodrigues, Fausto Almeida   +13 more
wiley   +1 more source

Variable gp43 secretion by Paracoccidioides brasiliensis clones obtained by two different culture methods [PDF]

, 2005
The main objectives of this study were to obtain clones of Paracoccidioides brasiliensis by two methods (micromanipulation and plating assay) and to determine if the secretion of the 43-kDa glycoprotein (gp43) is dependent on the clonal culture.
Berzaghi, Rodrigo, Camargo, Zoilo Pires de, Silva, Silvia Helena M da   +2 more
core   +3 more sources

Climate Change, Natural Disasters, and Cutaneous Fungal Infections

International Journal of Dermatology, Volume 64, Issue 8, Page 1349-1355, August 2025.
ABSTRACT Fungal infections are an important source of morbidity and mortality that can manifest as superficial or invasive diseases. Diagnostic techniques for human fungal pathogens remain problematic, and multi‐drug resistance is emerging. This review addresses the potential emergence of new fungal pathogens in changing environments and reported ...
Aditya K. Gupta, Mary Thornbush, Tong Wang   +2 more
wiley   +1 more source

Proteomic analysis of Paracoccidioides brasiliensis complex isolates: Correlation of the levels of differentially expressed proteins with in vivo virulence.

PLoS ONE, 2019
BACKGROUND:Paracoccidioidomycosis (PCM) is a systemic mycosis commonly found in Latin America that is caused by distinct species of Paracoccidioides genus: Paracoccidioides brasiliensis complex (S1, PS2, PS3 and PS4) and Paracoccidioides lutzii.
Cristiane Candida do Amaral, Geisa Ferreira Fernandes, Anderson Messias Rodrigues, Eva Burger, Zoilo Pires de Camargo   +4 more
doaj   +1 more source

Negative immunodiffusion test results obtained with sera of paracoccidioidomycosis patients may be related to low-avidity immunoglobulin G2 antibodies directed against carbohydrate epitopes [PDF]

, 2003
Immunodiffusion (ID) is the serologic test most frequently used for the diagnosis and posttherapy follow-up of patients with paracoccidioidomycosis (PCM).
Blotta, Maria Heloisa SL, Camargo, Zoilo P. de, Mamoni, Ronei L., Neves, Andreia R., Rossi, Claudio L.   +4 more
core   +3 more sources

Paracoccidioides brasiliensis-gp43 used as paracoccidioidin [PDF]

Medical Mycology, 1996
A purified glycoprotein of 43,000 daltons from Paracoccidioides brasiliensis (gp43) was tested as paracoccidioidin in delayed-type hypersensitivity (DTH) tests in both experimental animals (guinea pig and mice) and patients with paracoccidioidomycosis (PCM). The gp43 paracoccidioidin was compared with the traditional Fava Netto antigen (AgFN).
Saraiva, E. C O, Altemani, A., Franco, M. F., Unterkircher, C. S., Camargo, Z. P.   +4 more
openaire   +3 more sources

A steric gate prevents mutagenic dATP incorporation opposite 8‐oxo‐deoxyguanosine in mitochondrial DNA polymerases

The FEBS Journal, Volume 292, Issue 13, Page 3430-3448, July 2025.
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres, Carlos H. Trasviña‐Arenas, Alexandru Ionut Gilea, Upeksha C. Dissanayake, Missael Molina‐Jiménez, Paola L. García‐Medel, Corina Díaz‐Quezada, Tiziana Lodi, G. Andrés Cisneros, Enrico Baruffini, Luis G. Brieba   +10 more
wiley   +1 more source

Microdilution procedure for antifungal susceptibility testing of Paracoccidioides brasiliensis to amphotericin b and itraconazole

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
In vitro tests employing microdilution to evaluate fungal susceptibility to antifungal drugs are already standardized for fermentative yeasts. However, studies on the susceptibility of dimorphic fungi such as Paracoccidioides brasiliensis employing this ...
E Takahagi-Nakaira, MF Sugizaki, MTS Peraçoli   +2 more
doaj   +1 more source

DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis induces long-term protection in presence of regulatory T cells [PDF]

, 2013
Paracoccidioidomycosis is a granulomatous systemic mycosis endemic in Brazil and other Latin America countries. A DNA vaccine encoding the inununoprotective peptide 10 (P10) significantly reduced the fungal burden in mice when given prior to or after ...
Amorim, Juliana de, Magalhães, Adriana, Munoz, Julian Esteban, Nosanchuk, Joshua Daniel, Rittner, Glauce Mary Gomes, Taborda, Carlos Pelleschi, Travassos, Luiz Rodolpho   +6 more
core   +2 more sources

Understanding causes of morbidity and mortality in Southern Hemisphere small Odontoceti: a scoping review

Mammal Review, Volume 55, Issue 2, April 2025.
This review identifies key causes of morbidity and mortality in Southern Hemisphere small Odontoceti, highlighting significant anthropogenic threats and the enhanced need for conservation strategies. Key findings include high rates of entanglements and a diverse range of infectious pathogens. Abstract Marine mammals serve as sentinels for environmental
Rebecca Souter, Anne‐Lise Chaber, Luciana Möller, Lucy Woolford   +3 more
wiley   +1 more source