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Paracoccidiodomycosis (PCM) is the most important systemic mycosis in Brazil, and is usually associated with rural work. PCM is caused by inhalation of infective propagules of thermodimorphic fungi from the genus Paracoccidioides.
Beatriz da Silva Motta +6 more
doaj +1 more source
Foi realizado um inquérito epidemiológico sobre paracoccidioidomicose com gp43, em 118 operários no Noroeste do Paraná. A positividade foi de 43%, o que aliado às condições ambientais favoráveis ao desenvolvimento do fungo reforçam que essa região seja ...
Nair Fornajeiro +3 more
doaj +1 more source
Identification of human plasma proteins associated with the cell wall of the pathogenic fungus Paracoccidioides brasiliensis [PDF]
Paracoccidioides brasiliensis and Paracoccidioides lutzii are thermodimorphic species that cause paracoccidioidomycosis. the cell wall is the outermost fungal organelle to form an interface with the host.
Almeida, Igor C. +8 more
core +2 more sources
Extracellular vesicles from Paracoccidioides brasiliensis induced M1 polarization in vitro
Extracellular vesicles (EVs) released by eukaryotes, archaea, and bacteria contain proteins, lipids, polysaccharides, and other molecules. The cargo analysis of EVs shows that they contain virulence factors suggesting a role in the pathogenesis of ...
T. D. da Silva +3 more
semanticscholar +1 more source
Fungal DNA‐barcoding on a chip: Magnetoresistive biosensors for yeast infection diagnosis
The development of a fungal pathogen identification chip is herein demonstrated. Hybridization dynamics were tested against 58 species in silico and 4 species on chip. 95% accuracy, 91% sensitivity, 98% specificity and femtomolar limit of detection were achieved. Future perspectives include the integration of sample pre‐treatment modules.
Maria Zolotareva +8 more
wiley +1 more source
The genus Paracoccidioides includes Paracoccidioides lutzii and the Paracoccidioides brasiliensis complex, which comprises four phylogenetic species. A key feature distinguishing planktonic growth from biofilm is the presence of a 3D extracellular matrix
Lariane Teodoro Oliveira +7 more
doaj +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder +4 more
wiley +1 more source
In this study, we evaluated the profile of anti-Paracoccidioides brasiliensis immunoglobulin isotypes in serum from patients with the acute and chronic forms of paracoccidioidomycosis, using the whole Paracoccidioides brasiliensis antigen and the antigen
Ana Paula Ferreira +6 more
doaj +1 more source
Paracoccidioidomycosis (PCM) is the main and most prevalent systemic mycosis in Latin America, that until recently, it was believed to be caused only by Paracoccidioides brasiliensis (P. brasiliensis). In 2006, researchers described three cryptic species:
Luciana Bonome Zeminian de Oliveira +9 more
doaj +1 more source
Serology of paracoccidioidomycosis [PDF]
This review provides the background for understanding the role of a battery of diagnostic methods in paracoccidioidomycosis (PCM). This systemic mycosis is a disease endemic in many regions of Latin America, with sporadic cases also occurring throughout ...
Camargo, Zoilo Pires de
core +1 more source

