Results 81 to 90 of about 36,345 (255)

The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells

Frontiers in Immunology, 2018
Plasmacytoid dendritic cells (pDCs), which have been extensively studied in the context of the immune response to viruses, have recently been implicated in host defense mechanisms against fungal infections.
N. W. Preite, C. Feriotti, D. Souza de Lima, Bruno Borges da Silva, A. Condino-Neto, A. Pontillo, V. Calich, F. V. Loures   +7 more
semanticscholar   +1 more source

Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses

Journal of Extracellular Biology, Volume 4, Issue 8, August 2025.
ABSTRACT Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate interactions between fungal cells and hosts, significantly influencing the pathogen‐host relationship ...
Caroline P. de Rezende, Patrick W. S. Santos, Renan A. Piraine, Virgínia C. Silvestrini, Julio C. J. Barbosa, Fabiana C. P. Valera, Edwin Tamashiro, Guilherme G. Podolski‐Gondim, Silvana M. Quintana, Rodrigo Calado, Roberto Martinez, Taicia P. Fill, Márcio L. Rodrigues, Fausto Almeida   +13 more
wiley   +1 more source

Complexo primário da paracoccidioidomicose e hipereosinofilia Primary complex of paracoccidioidomycosis and hypereosinophilia

Jornal Brasileiro de Pneumologia, 2009
A infecção primária por Paracoccidioides brasiliensis é observada raramente. Um paciente masculino de 28 anos de idade apresentou febre, sintomas respiratórios e indisposição durante três meses. Exames radiológicos evidenciaram infiltrado pulmonar apical
Roberto Martinez, Maria Janete Moya
doaj   +1 more source

Climate Change, Natural Disasters, and Cutaneous Fungal Infections

International Journal of Dermatology, Volume 64, Issue 8, Page 1349-1355, August 2025.
ABSTRACT Fungal infections are an important source of morbidity and mortality that can manifest as superficial or invasive diseases. Diagnostic techniques for human fungal pathogens remain problematic, and multi‐drug resistance is emerging. This review addresses the potential emergence of new fungal pathogens in changing environments and reported ...
Aditya K. Gupta, Mary Thornbush, Tong Wang   +2 more
wiley   +1 more source

REACTIVITY OF ANTI-GP43 ANTIBODIES FROM PARACOCCIDIOIDES BRASILIENSIS ANTISERUM WITH EXTRACTS FROM CUTANEOUS LESIONS OF LOBO'S DISEASE: PRELIMINARY NOTE

Revista do Instituto de Medicina Tropical de São Paulo, 1997
We demonstrated through several immunochemical tests the presence of GP-43 from P. brasiliensis in extracts of cutaneous lesions from Jorge Lobo's disease.
Mônica Scarpelli Martinelli VIDAL, Selma Aliotti PALACIOS, Natalina TAKAHASHI DE MELO, Carlos da Silva LACAZ   +3 more
doaj   +1 more source

Paracoccidioides brasiliensis GP43-derived peptides are potent modulators of local and systemic inflammatory response [PDF]

, 2012
Paracoccidioidomycosis is a systemic granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis. Its major antigen is a 43 kDa glycoprotein whose peptides embody different functions: P10 peptide, a T-cell epitope, :induces ...
Feitosa, Luciano dos Santos, Guereschi, Marcia Grando, Konno, Adriana Yumi de Camargo, Konno, Fabiana Toshie de Camargo, Lopes, Jose Daniel, Mariano, Mario, Maricato, Juliana Terzi, Vivanco, Bruno Camolese   +7 more
core   +2 more sources

Promising New Antifungal Treatment Targeting Chorismate Synthase from Paracoccidioides brasiliensis

Antimicrobial Agents and Chemotherapy, 2018
Paracoccidioidomycosis (PCM), caused by Paracoccidioides, is a systemic mycosis with granulomatous character and a restricted therapeutic arsenal. The aim of this work was to search for new alternatives to treat largely neglected tropical mycosis, such ...
Franciele Abigail Vilugron Rodrigues-Vendramini, Cidnei Marschalk, M. Toplak, P. Macheroux, P. Bonfim-Mendonça, T. Svidzinski, F. Seixas, É. S. Kioshima   +7 more
semanticscholar   +1 more source

A steric gate prevents mutagenic dATP incorporation opposite 8‐oxo‐deoxyguanosine in mitochondrial DNA polymerases

The FEBS Journal, Volume 292, Issue 13, Page 3430-3448, July 2025.
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres, Carlos H. Trasviña‐Arenas, Alexandru Ionut Gilea, Upeksha C. Dissanayake, Missael Molina‐Jiménez, Paola L. García‐Medel, Corina Díaz‐Quezada, Tiziana Lodi, G. Andrés Cisneros, Enrico Baruffini, Luis G. Brieba   +10 more
wiley   +1 more source

Gene knockdown in Paracoccidioides brasiliensis using antisense RNA [PDF]

, 2012
Paracoccidioides brasiliensis is a thermal dimorphic fungus which at host environment exhibits a multinucleated and multibudding yeast form. The cellular and molecular mechanisms underlying these phenotypes remain to be clarified, mostly due to the ...
Almeida, A. J., Menino, João F., Rodrigues, Fernando José dos Santos   +2 more
core   +1 more source

Understanding causes of morbidity and mortality in Southern Hemisphere small Odontoceti: a scoping review

Mammal Review, Volume 55, Issue 2, April 2025.
This review identifies key causes of morbidity and mortality in Southern Hemisphere small Odontoceti, highlighting significant anthropogenic threats and the enhanced need for conservation strategies. Key findings include high rates of entanglements and a diverse range of infectious pathogens. Abstract Marine mammals serve as sentinels for environmental
Rebecca Souter, Anne‐Lise Chaber, Luciana Möller, Lucy Woolford   +3 more
wiley   +1 more source