Results 61 to 70 of about 3,013,242 (348)
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
The human prerogative: a critical analysis of evidence-based and other paradigms of care in substance abuse treatment [PDF]
, 2010 Present-day substance abuse treatment is characterized by a compelling demand for applying evidence-based interventions. Vehement discussions between policymakers, practitioners and researchers illustrate this clash of differing paradigms.
Autrique, Annemarie +3 more
core +2 more sources
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
From normative towards positive epistemology: Problem of scientific fact [PDF]
Sociološki Pregled, 2009 In this article author provides a sketch of a twist from normative towards descriptive epistemology as a result of transformation of contemporary philosophy during the main occurrence known as Linguistic Turn.
Brdar Milan
doaj +1 more source
False Vacuum Chaotic Inflation: The New Paradigm? [PDF]
, 1994 Recent work is reported on inflation model building in the context of supergravity and superstrings, with special emphasis on False Vacuum (`Hybrid') Chaotic Inflation.
A. D. Linde +9 more
core +2 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Natural Hazards ResearchThe country wide lockdown implemented during 27th April to 14th June 2021 in order to prevent the spread of COVID-19 during the second wave in India. Effect of the restricted lockdown resulted in improved air quality.
Iranna Gogeri, K.C. Gouda, S.T. Aruna
doaj +1 more source
Developmental Robots - A New Paradigm [PDF]
, 2002 It has been proved to be extremely challenging for humans to program a robot to such a sufficient degree that it acts properly in a typical unknown human environment.
Weng, Juyang, Zhang, Yilu
core +1 more source
Nursing Philosophy, 2010 AbstractThe fictionalist paradigm is introduced, and differentiated from other paradigms, using the Lincoln & Guba template. Following an initial overview, the axioms of fictionalism are delineated by reference to standard metaphysical categories: the nature of reality, the relationship between knower and known, the possibility of generalization ...
openaire +4 more sources
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source