Results 11 to 20 of about 4,129 (201)

Hyperpolarization of Molecular Deuterium [PDF]

Angewandte Chemie, Volume 138, Issue 16, 13 April 2026.
Hyperpolarized molecular deuterium is generated and detected using a nonhydrogenative SABRE catalyst with nicotinamide. The resonance shows a strongly enhanced partially negative line, substrate‐dependent and sensitive to transient intermediates.
Theresa L. K. Hune, Anakin Aden, Julius F. Matz, Denis Moll, Ilya Kuprov, Stefan Glöggler   +5 more
wiley   +3 more sources

Rapid RASER MRI [PDF]

Angewandte Chemie International Edition, Volume 65, Issue 10, 2 March 2026.
Rapid RASER MRI allows for image acquisition without RF excitation. Instead, a population inversion on the nuclear spins is generated by SABRE hyperpolarization, which allows for self‐excitation through the RASER approach. When the desired transverse magnetization is built‐up, conventional EPI encoding is triggered to record the image.
Sören Lehmkuhl, Simon Fleischer, Jing Yang, Eduard Y. Chekmenev, Thomas Theis, Stephan Appelt, Jan G. Korvink, Mazin Jouda   +7 more
wiley   +2 more sources

15 N Reaction Monitoring at Low and Inhomogeneous Magnetic Fields Enabled by Hyperpolarization with Parahydrogen [PDF]

Chemistry – A European Journal, Volume 31, Issue 69, December 9, 2025.
15 N reaction monitoring at low and inhomogeneous fields enabled by PHIP. The concept was demonstrated at a magnetic field of 66 mT and 81 ppm inhomogeneity. Specifically, we measured the conversion of 15N‐boronobenzyl‐2‐styrylpyridinium to 15N‐2‐styrylpyridin.
Gonzalo Gabriel Rodriguez, Ruhuai Mei, Lisa Maria Fries, Stefan Glöggler   +3 more
wiley   +2 more sources

SABRE Ir-IMes Catalysis for the Masses [PDF]

Molecules
The Signal Amplification By Reversible Exchange (SABRE) technique provides enhancement of Nuclear Magnetic Resonance (NMR) signals up to several orders of magnitude using chemical exchange of a substrate and parahydrogen on an iridium complex. Therefore,
Izabelle Smith, Noah Terkildsen, Zachary Bender, Abubakar Abdurraheem, Shiraz Nantogma, Anna Samoilenko, Joseph Gyesi, Larisa M. Kovtunova, Oleg G. Salnikov, Igor V. Koptyug, Raphael Kircher, Danila A. Barskiy, Eduard Y. Chekmenev, Roman V. Shchepin   +13 more
doaj   +2 more sources

Improving the Catalyst Efficiency for Hyperpolarization of Pyruvate Derivatives by Means of Hydrogenative PHIP [PDF]

ChemMedChem, Volume 20, Issue 19, October 6, 2025.
Hyperpolarization (HP) of pyruvate is obtained by means of the parahydrogen based method named parahydrogen induced polarization‐side arm hydrogenation. Cationic rhodium complexes are usually applied for the hydrogenation of the precursor, but the concentration needed to obtain complete reduction in a few seconds of a batch of substrate is relatively ...
Ginevra Di Matteo, Oksana Bondar, Carla Carrera, Eleonora Cavallari, Sumit Mishra, Francesca Reineri   +5 more
wiley   +2 more sources

Technologies and Strategies for Metabolic and Molecular Imaging With Hyperpolarized MRI [PDF]

Journal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 310-327, February 2026.
ABSTRACT Conventional Magnetic Resonance Imaging (MRI) offers limited sensitivity for direct metabolic and molecular imaging using non‐proton nuclei due to low thermal nuclear spin polarization. Hyperpolarization (HP) technologies increase nuclear spin polarization by several orders of magnitude, overcoming this limitation to enable in vivo studies of ...
Alixander S. Khan, Christoffer Laustsen
wiley   +2 more sources

Through-bond and through-space radiofrequency amplification by stimulated emission of radiation [PDF]

Communications Chemistry
Radio Amplification by Stimulated Emission of Radiation (RASER) is a phenomenon observed during nuclear magnetic resonance (NMR) experiments with strongly negatively polarized systems. This phenomenon may be utilized for the production of very narrow NMR
Ivan A. Trofimov, Oleg G. Salnikov, Andrey N. Pravdivtsev, Henri de Maissin, Anna P. Yi, Eduard Y. Chekmenev, Jan-Bernd Hövener, Andreas B. Schmidt, Igor V. Koptyug   +8 more
doaj   +2 more sources

Spontaneous increasing of sensitivity and resolution in parahydrogen-induced hyperpolarization by RASER [PDF]

Magnetic Resonance Letters
Enhancing the sensitivity of nuclear magnetic resonance (NMR) technology has been the focus of NMR research for decades, which offers the potential to significantly expand its applications in chemistry, biology, and medical imaging.
Zeyu Zheng, Qiwei Peng, Huijun Sun, Xinchang Wang, Zhong Chen   +4 more
doaj   +2 more sources

Robust parahydrogen-induced polarization at high concentrations [PDF]

Science Advances
Parahydrogen-induced polarization (PHIP) is a potent technique for generating target molecules with high nuclear spin polarization. The PHIP process involves a chemical reaction between parahydrogen and a target molecule, followed by the transformation of nuclear singlet spin order into magnetization of a designated target nucleus through magnetic ...
Dagys, Laurynas, Korzeczek, Martin C., Parker, Anna J., Eills, James, Blanchard, John W., Bengs, Christian, Levitt, Malcolm H., Knecht, Stephan, Schwartz, Ilai, Plenio, Martin B.   +9 more
openaire   +7 more sources

Computer simulations of supercooled liquid hydrogen mixtures and the possible crystallization slowdown

Results in Physics, 2021
Metastable liquid mixtures of parahydrogen and orthodeuterium are studied theoretically by means of computer simulations. No reduced propensity of the mixture to undergo crystallization is observed, compared to that of pure liquid parahydrogen.
Massimo Boninsegni
doaj   +1 more source