Results 31 to 40 of about 2,750 (239)

Spontaneous increasing of sensitivity and resolution in parahydrogen-induced hyperpolarization by RASER [PDF]

Magnetic Resonance Letters
Enhancing the sensitivity of nuclear magnetic resonance (NMR) technology has been the focus of NMR research for decades, which offers the potential to significantly expand its applications in chemistry, biology, and medical imaging.
Zeyu Zheng, Qiwei Peng, Huijun Sun, Xinchang Wang, Zhong Chen   +4 more
doaj   +2 more sources

Intermolecular Nuclear Spin Hyperpolarization Transfer via Cross-Relaxation Triggers RASER of Solute Molecules. [PDF]

Angew Chem Int Ed Engl
Radiofrequency amplification by stimulated emission of radiation (RASER) of solutes was achieved via parahydrogen‐induced polarization (PHIP) and polarization transfer from the produced hyperpolarization donors to solutes via the intermolecular nuclear Overhauser effect (NOE).
Trofimov IA, Yi AP, Salnikov OG, Pravdivtsev AN, de Maissin H, Chekmenev EY, Hövener JB, Schmidt AB, Koptyug IV.   +8 more
europepmc   +3 more sources

Parahydrogen-induced polarization of 14N nuclei

Angewandte Chemie International Edition
Abstract Hyperpolarization techniques provide a dramatic increase in sensitivity of nuclear magnetic resonance spectroscopy and imaging. In spite of the outstanding progress in solution‐state hyperpolarization of spin‐1/2 nuclei, hyperpolarization of quadrupolar nuclei remains challenging.
Salnikov, Oleg G., Trofimov, Ivan A., Bender, Zachary T., Trepakova, Alexandra I., Xu, Jingyan, Wibbels, Garrett L., Shchepin, Roman V., Koptyug, Igor V., Barskiy, Danila A.   +8 more
openaire   +5 more sources

Rapid RASER MRI. [PDF]

Angew Chem Int Ed Engl
Rapid RASER MRI allows for image acquisition without RF excitation. Instead, a population inversion on the nuclear spins is generated by SABRE hyperpolarization, which allows for self‐excitation through the RASER approach. When the desired transverse magnetization is built‐up, conventional EPI encoding is triggered to record the image.
Lehmkuhl S, Fleischer S, Yang J, Chekmenev EY, Theis T, Appelt S, Korvink JG, Jouda M.   +7 more
europepmc   +2 more sources

Robust parahydrogen-induced polarization at high concentrations [PDF]

Science Advances
Parahydrogen-induced polarization (PHIP) is a potent technique for generating target molecules with high nuclear spin polarization. The PHIP process involves a chemical reaction between parahydrogen and a target molecule, followed by the transformation of nuclear singlet spin order into magnetization of a designated target nucleus through magnetic ...
Dagys, Laurynas, Korzeczek, Martin C., Parker, Anna J., Eills, James, Blanchard, John W., Bengs, Christian, Levitt, Malcolm H., Knecht, Stephan, Schwartz, Ilai, Plenio, Martin B.   +9 more
openaire   +7 more sources

Hyperpolarization of Molecular Deuterium [PDF]

Angew Chem Int Ed Engl
Hyperpolarized molecular deuterium is generated and detected using a nonhydrogenative SABRE catalyst with nicotinamide. The resonance shows a strongly enhanced partially negative line, substrate‐dependent and sensitive to transient intermediates.
Hune T, Aden A, Matz J, Moll D, Kuprov I, Glöggler S.   +5 more
europepmc   +3 more sources

Efficient polarization redistribution in hyperpolarized 1-D-propane produced via pairwise parahydrogen addition

Journal of Magnetic Resonance Open, 2023
Parahydrogen-Induced Polarization (PHIP) is NMR hyperpolarization technique that has matured from fundamental science to a biomedical tool for production of hyperpolarized MRI contrast agents. The spin order of nascent parahydrogen-derived protons can be
Nuwandi M. Ariyasingha, Shiraz Nantogma, Anna Samoilenko, Oleg G. Salnikov, Nikita V. Chukanov, Larisa M. Kovtunova, Igor V. Koptyug, Eduard Y. Chekmenev   +7 more
doaj   +1 more source

Computer simulations of supercooled liquid hydrogen mixtures and the possible crystallization slowdown

Results in Physics, 2021
Metastable liquid mixtures of parahydrogen and orthodeuterium are studied theoretically by means of computer simulations. No reduced propensity of the mixture to undergo crystallization is observed, compared to that of pure liquid parahydrogen.
Massimo Boninsegni
doaj   +1 more source

¹⁵N Reaction Monitoring at Low and Inhomogeneous Magnetic Fields Enabled by Hyperpolarization with Parahydrogen. [PDF]

Chemistry
15 N reaction monitoring at low and inhomogeneous fields enabled by PHIP. The concept was demonstrated at a magnetic field of 66 mT and 81 ppm inhomogeneity. Specifically, we measured the conversion of 15N‐boronobenzyl‐2‐styrylpyridinium to 15N‐2‐styrylpyridin.
Rodriguez GG, Mei R, Fries LM, Glöggler S.   +3 more
europepmc   +2 more sources

Geminal parahydrogen-induced polarization: accumulating long-lived singlet order on methylene proton pairs [PDF]

Magnetic Resonance, 2020
In the majority of hydrogenative parahydrogen-induced polarization (PHIP) experiments, the hydrogen molecule undergoes pairwise cis addition to an unsaturated precursor to occupy vicinal positions on the product molecule.
L. Dagys, B. Ripka, M. Leutzsch, G. A. I. Moustafa, J. Eills, J. F. P. Colell, M. H. Levitt   +6 more
doaj   +1 more source