Results 71 to 80 of about 736 (155)

Consensus recommendations for hyperpolarized [1‐13C]pyruvate MRI multi‐center human studies

Magnetic Resonance in Medicine, Volume 94, Issue 4, Page 1386-1400, October 2025.
Abstract MRI of hyperpolarized (HP) [1‐13C]pyruvate allows in vivo assessment of metabolism and has translated into human studies across diseases at 15 centers worldwide. To determine consensus on best practice for multi‐center studies for development of clinical applications.
Shonit Punwani, Peder E. Z. Larson, Christoffer Laustsen, Jan VanderMeulen, Jan Henrik Ardenkjær‐Larsen, Adam W. Autry, James A. Bankson, Jenna Bernard, Robert Bok, Lotte Bonde Bertelsen, Jenny Che, Albert P. Chen, Rafat Chowdhury, Arnaud Comment, Charles H. Cunningham, Duy Dang, Ferdia A. Gallagher, Adam Gaunt, Yangcan Gong, Jeremy W. Gordon, Ashley Grimmer, James Grist, Esben Søvsø Szocska Hansen, Mathilde Hauge Lerche, Richard L. Hesketh, Jan‐Bernd Hoevener, Ching‐Yi Hsieh, Kayvan R. Keshari, Sebastian Kozerke, Titus Lanz, Dirk Mayer, Mary McLean, Jae Mo Park, Jim Slater, Damian Tyler, Jean‐Luc Vanderheyden, Cornelius von Morze, Fulvio Zaccagna, Vlad Zaha, Duan Xu, Daniel Vigneron, The HP 13C MRI Consensus Group, Lotte Bonde Bertelsen, Nikolaj Bøgh, Esben Søvsø Szocska Hansen, Christoffer Laustsen, Jack Miller, Michael Vaeggemose, Jonas Steinhauser, Ching‐Yi Hsieh, Gigin Lin, Max Fuetterer, Sebastian Kozerke, Albert Chen, Arnaud Comment, Adam Gaunt, Justin Lau, Avi Leftin, Rolf Schulte, Jean‐Luc Vanderheyden, Irene Marco Rius, Jan‐Bernd Hoevener, Thomas C Booth, Mor Mishkovsky, Christopher Michael Walker, Jim Bankson, Kayvan Keshari, Ramona Woitek, Yuhei Takado, Crystal Vasquez, Sebastien Serres, Christoph A. Müller, Joel Floyd, Titus Lanz, Jan Henrik Ardenkjær‐Larsen, Andrea Capozzi, Mathilde Hauge Lerche, Martin Grashei, Franz Schilling, Geoffrey J Topping, Frits van Heijster, Adam Autry, Jenna Bernard, Bob Bok, Myriam Chaumeil, Jenny Che, Duy Dang, Jeremy Gordon, Yaewon Kim, John Kurhanewicz, Peder Larson, Yan Li, Michael Ohliger, Jim Slater, Renuka Sriram, Dan Vigneron, Zhen Jane Wang, Duan Xu, Ashley Grimmer, Mary McLean, Fulvio Zaccagna, Ferdia Gallagher, Rafat Chowdhury, Yangcan Gong, Shonit Punwani, Richard Hesketh, Jeraj Hassan, Andreas Kjaer, Matthew Merritt, Michael Bock, Andreas Schmidt, Dirk Mayer, Myounghee Lee, James Grist, Damian Tyler, Sarah Birkhoelzer, Jordan McGing, Aaron Axford, Oliver Rider, Fatemeh Khashami, Craig Malloy, Jae Mo Park, Vlad Zaha, Sung‐Han Lin, Junjie Ma, Charles Cunningham, Cornelius von Morze   +126 more
wiley   +1 more source

A pathway toward clinical translation of hyperpolarized [1,4‐13C2,2,3‐d2]fumarate as an imaging biomarker for early cellular necrosis in vivo

Magnetic Resonance in Medicine, Volume 94, Issue 3, Page 1202-1217, September 2025.
Abstract Purpose The detection of hyperpolarized carbon‐13 (HP 13C)‐fumarate conversion to 13C‐malate using 13C‐MRSI is a biomarker for early detection of cellular necrosis. Here, we describe the translation of HP 13C‐fumarate as a novel human imaging agent, including the evaluation of biocompatibility and scaling up of the hyperpolarization methods ...
Jonathan R. Birchall, Pascal Wodtke, Ashley Grimmer, Esben S. S. Hansen, Lotte B. Bertelsen, Nikolaj Bøgh, Marta Wylot, Maria J. Zamora‐Morales, Otso Arponen, Ines Horvat‐Menih, Elizabeth C. Latimer, Fung Tan, Evita Pappa, Johann Graggaber, Joseph Cheriyan, Kelly Holmes, Matthew J. Locke, Helen Sladen, Joan Boren, Mikko I. Kettunen, Anita Chhabra, Ian B. Wilkinson, Christoffer Laustsen, Kevin Brindle, Mary A. McLean, Ferdia A. Gallagher   +25 more
wiley   +1 more source

Assessing a hyperpolarized [1-13C]-labeled alanine derivative enhanced via parahydrogen for in vivo studies

Journal of Magnetic Resonance Open
Magnetic Resonance Imaging (MRI) is a valuable non-invasive technique widely used in clinical diagnostics; however, its sensitivity is limited, posing challenges in various medical conditions.
Lisa M. Fries, Denis Moll, Ruhuai Mei, Theresa L․ K․ Hune, Josef Elsaßer, Stefan Glöggler   +5 more
doaj   +1 more source

Parahydrogen discriminated PHIP at low magnetic fields

Journal of Magnetic Resonance, 2015
Parahydrogen induced polarization (PHIP) is a powerful hyperpolarization technique. However, as the signal created has an anti-phase characteristic, it is subject to signal cancellation when the experiment is carried out in inhomogeneous magnetic fields or in low fields that lack the necessary spectral resolution.
Prina, Ignacio, Buljubasich Gentiletti, Lisandro, Acosta, Rodolfo Héctor   +2 more
openaire   +3 more sources

Hydrogenation Reaction on Pd-Cu Bimetallic Catalysts: A Parahydrogen-Induced Polarization Study

Chinese Journal of Magnetic Resonance, 2018
Hydrogenation reaction of propyne on Pd-Cu bimetallic catalysts was studied using the heterogeneous parahydrogen-induced polarization (PHIP) nuclear magnetic resonance (NMR) technique.
WANG Wei-yu, HU Han, XU Jun, DENG Feng
doaj   +1 more source

Measurement of the weak nucleon-nucleon interaction by polarized cold neutron capture on protons

EPJ Web of Conferences, 2014
The NPDGamma Experiment at the Spallation Neutron Source at Oak Ridge National Laboratory is measuring the parity-odd correlation between the neutron spin and the direction of the emitted photon in the capture of polarized cold neutrons on protons.
Alarcon R., Blyth D.
doaj   +1 more source

Improved 2D hydride detection for NMR-chemosensing via p‐H2 Hyperpolarization

Journal of Magnetic Resonance Open
2D NMR zero-quantum spectroscopy offers a robust and convenient way to resolve hydride resonances in non-hydrogenative ParaHydrogen Induced Polarization experiments.
Ruud L.E.G. Aspers, Marco Tessari
doaj   +1 more source

Current state of the art of analyte scope in urine metabolome analysis by non-hydrogenative PHIP

Journal of Magnetic Resonance Open
Non-hydrogenative PHIP (nh-PHIP) is an NMR signal enhancement technique that offers several orders of magnitude gains in detection sensitivity. It is one of the few hyperpolarization methods that have been demonstrated to be applicable to chemical ...
Nele Reimets, Kerti Ausmees, Indrek Reile   +2 more
doaj   +1 more source

Density Matrix of Two Spin-1/2 Particles: Pure and Mixed States

Concepts in Magnetic Resonance: Part A, Bridging Education and Research
The density matrix of an arbitrary pure state of a system consisting of two spin-1/2 particles is derived from the Pauli spin angular momentum operators.
Eric R. Johnston
doaj   +1 more source

Quantum Monte Carlo study of thin parahydrogen films on graphite

Results in Physics
The low-temperature properties of one and two layers of parahydrogen adsorbed on graphite are investigated theoretically through Quantum Monte Carlo simulations. We adopt a microscopic model that explicitly includes the corrugation of the substrate.
Jie-Ru Hu, Massimo Boninsegni
doaj   +1 more source